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Endoscopy Is Relatively Safe in Patients with Acute Ischemic Stroke and Gastrointestinal Hemorrhage
ConclusionsGastrointestinal endoscopy can be safely performed in a substantial number of patients with AIS and GIH.
Source: Digestive Diseases and Sciences - December 5, 2018 Category: Gastroenterology Source Type: research

Mo1147 SAFETY OF GASTROINTESTINAL ENDOSCOPY IN PATIENTS WITH STROKE IN THE SETTING OF GASTROINTESTINAL HEMORRHAGE: ANALYSIS OF NATIONWIDE INPATIENT SAMPLE (NIS) DATABASE
Gastrointestinal (GI) hemorrhage is a common complication in patients with cerebrovascular accidents. Reported incidence has ranged from 1% to 8% in several published studies. We studied a national inpatient database to assess the effects of GI endoscopy on mortality and length of hospital stay among patients with acute stroke.
Source: Gastrointestinal Endoscopy - May 30, 2018 Category: Gastroenterology Authors: Mohamed Tausif Siddiqui, Mohammad Bilal, Lakshmi Asritha Gollapudi, Jonathan Barsa, Khwaja F. Haq, Zahava C. Farkas, Virendra Tewari Tags: Monday abstract Source Type: research

Endoscopy in Patients on Antiplatelet Agents and Anticoagulants
Opinion statementManagement of patients on anticoagulant or antiplatelet therapy undergoing endoscopy presents a balance of risks between haemorrhage due to the procedure, and thrombosis due to discontinuation of antithrombotic therapy. Haemorrhage is usually controllable endoscopically, but thrombosis could, on occasion, result in myocardial infarction or stroke, with permanent disability or death. For elective procedures, there is adequate time to plan best management of antithrombotic therapy. International guidelines have been published, but recommendations are based on limited evidence and consultation with appropriat...
Source: Current Treatment Options in Gastroenterology - May 25, 2017 Category: Gastroenterology Source Type: research

Mo1074 Outcomes of Gastrointestinal Hemorrhage in the Setting of Novel Versus Traditional Antithrombotic Agents
The objective of our study was to compare outcomes among patients presenting with GI bleed that were prescribed novel versus traditional antithrombotic agents.
Source: Gastrointestinal Endoscopy - April 28, 2017 Category: Gastroenterology Authors: Jonathan I. Chang, Elizabeth Dong, Karl Kwok, Bechien U. Wu Tags: Monday – ASGE poster Source Type: research

Transesophageal Echocardiography Complications in Adult Cardiac Surgery: A Retrospective Cohort Study
Conclusions The overall incidence of TEE complications after cardiac surgery was 1.4%. Advanced age, low body mass index, complexity of procedure, prior stroke, prolonged bypass time, and return to the operating room appear to be significant risk factors for TEE complications.
Source: The Annals of Thoracic Surgery - September 17, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Transesophageal Echocardiography Complications in Adult Cardiac Surgery: A Retrospective Cohort Study.
CONCLUSIONS: The overall incidence of TEE complications after cardiac surgery was 1.4%. Advanced age, low body mass index, complexity of procedure, prior stroke, prolonged bypass time, and return to the operating room appear to be significant risk factors for TEE complications. PMID: 27646612 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - September 15, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Purza R, Ghosh SB, Walker C, Hiebert B, Koley L, Mackenzie GS, Grocott HP Tags: Ann Thorac Surg Source Type: research

All bleeding stops — but does idarucizumab (Praxbind) make it stop faster?
3.5 out of 5 stars Persistent life-threatening hemorrhage after administration of idarucizumab. Alhashem HM et al. Am J Emerg Med 2016 June 30 [Epub ahead of print] Reference Dabigatran (Pradaxa) is a direct thrombin inhibitor approved for stroke and embolism prophylaxis in patients with non-valve-related atrial fibrillation. When it was first released in 2008, a major disincentive to widespread use was the lack of a reliable reversal agent to treat major bleeds, or to administer before necessary invasive procedures. In October 2015, the U.S. Food and Drug Administration approved idarucizumab (Praxbind), a monoclonal ant...
Source: The Poison Review - July 27, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical anticoagulant hemorrhage idarucizumab pradaxa praxbind reversal agent Source Type: news

Guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment
have been produced by the Japan Gastroenterological Endoscopy Society in collaboration with the Japan Circulation Society, the Japanese Society of Neurology, the Japan Stroke Society, the Japanese Society on Thrombosis and Hemostasis and the Japan Diabetes Society. Previous guidelines from the Japan Gastroenterological Endoscopy Society have focused primarily on prevention of hemorrhage after gastroenterological endoscopy as a result of continuation ofantithrombotic therapy, without considering the associated risk of thrombosis. The new edition of the guidelines includes discussions of gastroenterological hemorrhage assoc...
Source: Digestive Endoscopy - November 12, 2013 Category: Gastroenterology Authors: Kazuma Fujimoto, Mitsuhiro Fujishiro, Mototsugu Kato, Kazuhide Higuchi, Ryuichi Iwakiri, Choitsu Sakamoto, Shinichiro Uchiyama, Atsunori Kashiwagi, Hisao Ogawa, Kazunari Murakami, Tetsuya Mine, Junji Yoshino, Yoshikazu Kinoshita, Masao Ichinose, Toshiyuki Tags: Guideline Source Type: research

Osler-Weber-Rendu syndrome simulating pulmonary metastasis
Osler–Weber–Rendu syndrome, also known as hereditary haemorrhagic telangiectasia (HHT), is an autosomal dominant disorder of abnormal blood vessel formation manifesting as telangiectasias and arteriovenous malformations (AVMs). The criteria for the diagnosis of HHT are epistaxis, multiple telangiectasias at mucocutaneous surfaces, AVMs in larger organ systems, and a family history of HHT.1–3 Recurrent epistaxis is the most common presenting complaint. Cerebral AVMs occur in about 10–20% of patients with HHT, and are associated with high mortality and morbidity due to stroke or brain abscess. MRI is ...
Source: Postgraduate Medical Journal - February 15, 2013 Category: Journals (General) Authors: Pereira e Silva, J. L., Zanetti, G., Marchiori, E. Tags: GI bleeding, Genetics, Echocardiography, Stroke, Radiology, Surgical diagnostic tests, General surgery, Radiology (diagnostics), Ear, nose and throat/otolaryngology, Epidemiology Images in medicine Source Type: research

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