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Condition: Hemorrhagic Stroke
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Total 12507 results found since Jan 2013.

Delays in Door-to-Needle Times and Their Impact on Treatment Time and Outcomes in Get With The Guidelines-Stroke Clinical Sciences
Conclusions—Hospital and eligibility delays such as delay diagnosis and inability to determine eligibility were associated with longer door-to-needle times. Improved stroke recognition and management of acute comorbidities may help to reduce door-to-needle times.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Noreen Kamal, Shubin Sheng, Ying Xian, Roland Matsouaka, Michael D. Hill, Deepak L. Bhatt, Jeffrey L. Saver, Mathew J. Reeves, Gregg C. Fonarow, Lee H. Schwamm, Eric E. Smith Tags: Quality and Outcomes, Ischemic Stroke Original Contributions Source Type: research

Reciprocal Interaction of 24-Hour Blood Pressure Variability and Systolic Blood Pressure on Outcome in Stroke Thrombolysis Clinical Sciences
Background and Purpose—Significance and management of blood pressure (BP) changes in acute stroke care are unclear. Here, we aimed to investigate the impact of 24-hour BP variability (BPV) on outcome in patients with acute ischemic stroke treated with intravenous thrombolysis.Methods—From the Safe Implementation of Treatment in Stroke International Stroke Thrombolysis registry, 28 976 patients with documented pre-treatment systolic BP at 2 and 24 hours were analyzed. The primary measure of BP variability was successive variability. Data were preprocessed using coarsened exact matching. We assessed early neurological ...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Lars Kellert, Christian Hametner, Niaz Ahmed, Geraldine Rauch, Mary J. MacLeod, Francesco Perini, Kennedy R. Lees, Peter A. Ringleb Tags: Ischemic Stroke Original Contributions Source Type: research

Real-World Setting Comparison of Nonvitamin-K Antagonist Oral Anticoagulants Versus Vitamin-K Antagonists for Stroke Prevention in Atrial Fibrillation Clinical Sciences
Conclusions—This meta-analysis confirms the main findings of the randomized controlled trials of dabigatran, rivaroxaban, and apixaban in the real-world setting and, hence, strengthens their validity.
Source: Stroke - August 28, 2017 Category: Neurology Authors: George Ntaios, Vasileios Papavasileiou, Konstantinos Makaritsis, Konstantinos Vemmos, Patrik Michel, Gregory Y.H. Lip Tags: Arrhythmias, Secondary Prevention, Meta Analysis, Mortality/Survival, Ischemic Stroke Original Contributions Source Type: research

Palliative Care for Hospitalized Patients With Stroke Clinical Sciences
This study explores patterns of palliative care utilization and death in hospitalized patients with stroke across the United States.Methods—Using the 2010 to 2012 nationwide inpatient sample databases, we included all patients discharged with stroke identified by International Classification of Diseases-Ninth Revision codes. Strokes were subclassified as ischemic, intracerebral, and subarachnoid hemorrhage. We compared demographics, comorbidities, procedures, and outcomes between patients with and without a palliative care encounter (PCE) as defined by the International Classification of Diseases-Ninth Revision code V66....
Source: Stroke - August 28, 2017 Category: Neurology Authors: Tarvinder Singh, Steven R. Peters, David L. Tirschwell, Claire J. Creutzfeldt Tags: Race and Ethnicity, Quality and Outcomes, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

White Matter Hyperintensity Volume and Outcome of Mechanical Thrombectomy With Stentriever in Acute Ischemic Stroke Brief Report
Conclusions—Mechanical thrombectomy using stentrievers seems to be safe in selected patients with acute ischemic stroke with large vessel occlusion, nonwithstanding the severity of WMH burden in this population. Larger prospective studies are warranted to validate these findings.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Kunakorn Atchaneeyasakul, Thabele Leslie-Mazwi, Kathleen Donahue, Anne-Katrin Giese, Natalia S. Rost Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

PROMIS GH (Patient-Reported Outcomes Measurement Information System Global Health) Scale in Stroke Clinical Sciences
The objective of this study was to evaluate the psychometric properties of PROMIS GH in patients with ischemic stroke and intracerebral hemorrhage.Methods—PROMIS GH and 6 PROMIS domain scales measuring same/similar constructs were electronically collected on 1102 patients with ischemic and hemorrhagic strokes at various stages of recovery from their stroke who were seen in a cerebrovascular clinic from October 12, 2015, through June 2, 2017. Confirmatory factor analysis was performed to evaluate the adequacy of 2-factor structure of component scores. Test–retest reliability and convergent validity of PROMIS GH items an...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Irene L. Katzan, Brittany Lapin Tags: Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Common Variants Within Oxidative Phosphorylation Genes Influence Risk of Ischemic Stroke and Intracerebral Hemorrhage Clinical Sciences
Conclusions— This pathway analysis demonstrates association between common genetic variants within OXPHOS genes and stroke. The associations for small vessel stroke and deep ICH suggest that genetic variation in OXPHOS influences small vessel pathobiology. Further studies are needed to identify culprit genetic variants and assess their functional consequences.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Anderson, C. D., Biffi, A., Nalls, M. A., Devan, W. J., Schwab, K., Ayres, A. M., Valant, V., Ross, O. A., Rost, N. S., Saxena, R., Viswanathan, A., Worrall, B. B., Brott, T. G., Goldstein, J. N., Brown, D., Broderick, J. P., Norrving, B., Greenberg, S. M Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Brain Circulation and Metabolism, Genetics of Stroke Clinical Sciences Source Type: research

External Validation of the SEDAN Score for Prediction of Intracerebral Hemorrhage in Stroke Thrombolysis Clinical Sciences
Conclusions— In this very large data set, the predictive and discriminatory performances of the SEDAN score were only moderate for SICH per ECASS II and low for SICH per SITS–Monitoring Study.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Mazya, M. V., Bovi, P., Castillo, J., Jatuzis, D., Kobayashi, A., Wahlgren, N., Ahmed, N. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Caffeine-Containing Medicines Increase the Risk of Hemorrhagic Stroke Clinical Sciences
Conclusions— These results suggest that use of CCMs is associated with increased risk of HS, both subarachnoid hemorrhage and intracerebral hemorrhage.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Lee, S.-M., Choi, N.-K., Lee, B.-C., Cho, K.-H., Yoon, B.-W., Park, B.-J. Tags: Behavioral Changes and Stroke, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Intracerebral Hemorrhage, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

Combined Approach to Lysis Utilizing Eptifibatide and Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke-Enhanced Regimen Stroke Trial Major Clinical Trial
Conclusions— The combined regimen of intravenous rt-PA and eptifibatide studied in this trial was safe and provides evidence that a phase III trial is warranted to determine efficacy of the regimen. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00894803.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Pancioli, A. M., Adeoye, O., Schmit, P. A., Khoury, J., Levine, S. R., Tomsick, T. A., Sucharew, H., Brooks, C. E., Crocco, T. J., Gutmann, L., Hemmen, T. M., Kasner, S. E., Kleindorfer, D., Knight, W. A., Martini, S., McKinney, J. S., Meurer, W. J., Meye Tags: Emergency treatment of Stroke, Antiplatelets, Thrombolysis Major Clinical Trial Source Type: research

The iScore Predicts Efficacy and Risk of Bleeding in the National Institute of Neurological Disorders and Stroke Tissue Plasminogen Activator Stroke Trial
The iScore is a validated tool to estimate outcomes after an acute ischemic stroke. A previous study showed the iScore can predict clinical response and risk of intracerebral hemorrhage (ICH) after administration of tissue plasminogen activator (tPA). We applied the iScore (www.sorcan.ca/iscore) to participants in the National Institute of Neurological Disorders and Stroke tPA stroke trials to evaluate its ability to estimate clinical response and risk of ICH after thrombolysis. Based on results from our previous study, patients were stratified a priori into iScore
Source: Journal of Stroke and Cerebrovascular Diseases - October 26, 2012 Category: Neurology Authors: Gustavo Saposnik, Andrew Demchuk, Jack V. Tu, S. Claiborne Johnston, Stroke Outcomes Research Canada (SORCan) Working Group Tags: Original Articles Source Type: research

Impact of Stroke Care Unit on Patient Outcomes in a Community Hospital Clinical Sciences
Conclusions— Establishing a SCU in a community hospital not only increases the survival of stroke patients, but also the proportion of patients discharged home to live independently. The benefits of SCU reported in larger tertiary centers extend to smaller community hospitals with more limited resources.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Tamm, A., Siddiqui, M., Shuaib, A., Butcher, K., Jassal, R., Muratoglu, M., Buck, B. H. Tags: Health policy and outcome research, Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Safety of Thrombolysis in Patients With Acute Ischemic Stroke and Cerebral Cavernous Malformations Brief Reports
Conclusions— Given the limitations of our study (mainly low number of patients with CCM), the risk of thrombolysis-associated hemorrhage in patients with CCM remains uncertain. Although our data do not suggest an increased hazard from thrombolysis in patients with CCM, larger studies are necessary to determine definitively the influence of CCMs on parenchymal hemorrhage and symptomatic intracerebral hemorrhage.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Erdur, H., Scheitz, J. F., Tutuncu, S., Fiebach, J. B., Endres, M., Werring, D. J., Nolte, C. H. Tags: Acute Cerebral Infarction, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Emergency treatment of Stroke, Intracerebral Hemorrhage, Thrombolysis Brief Reports Source Type: research

Race/Ethnic Differences in the Risk of Hemorrhagic Complications Among Patients With Ischemic Stroke Receiving Thrombolytic Therapy Clinical Sciences
Conclusions— In patients with stroke receiving tPA, hemorrhagic complications were slightly higher in blacks and Asians, but not in Hispanics compared with whites. Asians also faced significantly higher risk for sICH relative to other race/ethnic groups. Future studies are needed to evaluate whether reduction in tPA dose similar to that used in many Asian countries could improve the safety of tPA therapy in Asians in the United States with acute ischemic strokes while maintaining efficacy.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Mehta, R. H., Cox, M., Smith, E. E., Xian, Y., Bhatt, D. L., Fonarow, G. C., Peterson, E. D., for the Get With The Guidelines-Stroke Program Tags: Thrombolysis Clinical Sciences Source Type: research

Standard-Dose Intravenous Tissue-Type Plasminogen Activator for Stroke Is Better Than Low Doses Clinical Sciences
Conclusions— Our study suggests that standard-dose intravenous tPA for stroke had more favorable outcome without increasing the risk of symptomatic intracranial hemorrhage than low-dose tPA. For Asian people, 0.9 mg/kg should be the optimal dose of tPA to treat acute ischemic stroke.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Liao, X., Wang, Y., Pan, Y., Wang, C., Zhao, X., Wang, D. Z., Wang, C., Liu, L., Wang, Y., on behalf of the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China Investigators Tags: Acute Cerebral Infarction, Thrombolysis Clinical Sciences Source Type: research