• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Full-dose thrombolysis for a right middle cerebral artery stroke after an acute aortic dissection
We report a case of a patient with an acute right middle cerebral artery stroke due to an acute aortic dissection (Stanford Type A) who was treated with full dose IV r-tpa resulting in a good outcome.
Source: Annals of Indian Academy of Neurology - September 4, 2018 Category: Neurology Authors: Syed Omar Kazmi Oliver Achi Rahul Damani Source Type: research

Hemorrhagic stroke and cerebral venous thrombosis: rare neurological sequelae of chickenpox infection
Anuradha Mehta, Aanchal Arora, Manoj Sharma, Rupali Malik, Yogesh Chandra PorwalAnnals of Indian Academy of Neurology 2018 21(3):228-232 Chickenpox (varicella) is primarily a disease of childhood which occurs due to infection with varicella-zoster virus (VZV). Primary VZV infection is rare in adults due to exposure in early childhood in our country. In adults, it is associated with some serious systemic and neurological complications which can follow both primary infection and reactivation of VZV. Neurological sequelae caused by primary VZV infection are rare and include encephalitis, aseptic meningitis, myelitis, acute c...
Source: Annals of Indian Academy of Neurology - September 4, 2018 Category: Neurology Authors: Anuradha Mehta Aanchal Arora Manoj Sharma Rupali Malik Yogesh Chandra Porwal Source Type: research

Korean Clinical Practice Guidelines for Aneurysmal Subarachnoid Hemorrhage.
Authors: Cho WS, Kim JE, Park SQ, Ko JK, Kim DW, Park JC, Yeon JY, Chung SY, Chung J, Joo SP, Hwang G, Kim DY, Chang WH, Choi KS, Lee SH, Sheen SH, Kang HS, Kim BM, Bae HJ, Oh CW, Park HS, Quality Control Committees from the Korean Society of Cerebrovascular Surgeons, Society of Korean Endovascular Neurosurgeons, Korean Society of Interventional Neuroradiology, Korean Stroke Society and Korean Academy of Rehabilitation Medicine Abstract Despite advancements in treating ruptured cerebral aneurysms, an aneurysmal subarachnoid hemorrhage (aSAH) is still a grave cerebrovascular disease associated with a high rate of mo...
Source: Journal of Korean Neurosurgical Society - March 13, 2018 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Use of direct oral anticoagulants for stroke prevention in elderly patients with nonvalvular atrial fibrillation
ConclusionsDOACs are at least as effective as warfarin for stroke prevention in elderly patients with NVAF. Compared with warfarin, DOACs were associated with reduced risk of intracranial hemorrhage, while some DOACs demonstrated an increase in other bleeding events (e.g., gastrointestinal). The faster onset and offset of action and fewer food and drug interactions of DOACs may be an advantage over warfarin for some patients. Implications for practiceDOACs are an alternative to warfarin with overall equivalent safety and efficacy in elderly patients with NVAF, and may be preferable for some. Stroke risk must always be bala...
Source: Journal of the American Academy of Nurse Practitioners - August 14, 2017 Category: Nursing Authors: Lynn B. Oertel, Annemarie E. Fogerty Tags: REVIEW ‐ SPONSORED Source Type: research

Acute ischemic stroke treatment using mechanical thrombectomy: A study of 137 patients
Conclusion: MT is safe treatment and equally effective for both AC and PC LVO. With careful patient selection, clinical outcome in PC was comparable to AC despite delayed presentation and higher baseline NIHSS.
Source: Annals of Indian Academy of Neurology - August 10, 2017 Category: Neurology Authors: Rakeshsingh K Singh Vishal Annaji Chafale Rakesh Shyam Lalla Keyurkumar Chandrakantbhai Panchal Anil Pandurang Karapurkar Satish Vasant Khadilkar Pawan K Ojha Yogesh Godge Rakesh K Singh Rajesh Benny Source Type: research

Overweight teen boys have increased risk of stroke in later life
Conclusion The findings of this large longitudinal cohort study seem to demonstrate a link between being overweight aged 20 and an increased risk of stroke. This risk was regardless of whether the boy had been overweight aged 8 or not. There seemed to be no increased risk for boys who were overweight aged 8 but were a normal weight by the age of 20. The study was conducted before the obesity epidemic, and might be even more relevant today. But there are a number of considerations to take into account before we draw any conclusions: Participants were followed up until they were 52-68, so all the strokes occurred at a r...
Source: NHS News Feed - June 29, 2017 Category: Consumer Health News Tags: Obesity Pregnancy/child Source Type: news

Combined HMG-COA reductase and prenylation inhibition in treatment of CCM Medical Sciences
Cerebral cavernous malformations (CCMs) are common vascular anomalies that develop in the central nervous system and, more rarely, the retina. The lesions can cause headache, seizures, focal neurological deficits, and hemorrhagic stroke. Symptomatic lesions are treated according to their presentation; however, targeted pharmacological therapies that improve the outcome of CCM...
Source: Proceedings of the National Academy of Sciences - May 23, 2017 Category: Science Authors: Sayoko Nishimura, Ketu Mishra-Gorur, JinSeok Park, Yulia V. Surovtseva, Said M. Sebti, Andre Levchenko, Angeliki Louvi, Murat Gunel Tags: Biological Sciences Source Type: research

Systematic Review and Meta-Analysis of Cohort Studies Examining Effect of Anticoagulation and Risk of Cerebral Hemorrhage in patients with Cerebral Microbleeds (P2.276)
Conclusions:Results of this meta-analysis suggest that patients with CMBs started on anticoagulation after ischemic stroke are more likely to have ICH outcomes than patients without CMBs. However, the study was limited by small sample sizes based on extracted data and lack of quality prospective cohort studies meeting inclusion criteria. Further investigation is necessary to conclude increased risk of ICH in this patient population.Disclosure: Dr. Faheem has nothing to disclose. Dr. Wang has received research support from TEVA Pharmaceuticals Ltd. Dr. Gronseth has received personal compensation in an editorial capacity for...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Faheem, N., Wang, Y., Gronseth, G. Tags: Intracerebral Hemorrhage Source Type: research

Association between Leucocyte Count and Perihematomal Edema Growth After Primary Intracerebral Hemorrhage (N8.001)
Conclusions:Higher admission leucocyte count, particularly monocyte count, is associated with PHE growth. This suggests a potential role of inflammation in modulating PHE after ICH.Study Supported by: American Academy of Neurology and American Brain Foundation Clinical Research Training FellowshipDisclosure: Dr. Gusdon has nothing to disclose. Dr. Gialdini has nothing to disclose. Dr. Baradaran has nothing to disclose. Dr. Merkler has nothing to disclose. Dr. Iadecola has received personal compensation in an editorial capacity for the Journal of Neuroscience. Dr. Navi has nothing to disclose. Dr. Gupta has nothing to discl...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Gusdon, A., Gialdini, G., Baradaran, H., Merkler, A., Iadecola, C., Navi, B., Gupta, A., Kamel, H., Murthy, S. Tags: Neuroscience in the Clinic: Novel Therapeutic Targets in Critical Care Neurology: Intracerebral and Intraventricular Hemorrhage Source Type: research

Diagnostic errors in cerebrovascular disease: What are we missing?
Diagnostic error is the "failure to establish an accurate and timely explanation of the patient's health problems or communicate that explanation to the patient," according to the Institute of Medicine of the National Academies of Sciences.1 These errors occur pervasively in all settings of our health care system, including outpatient clinics, inpatient wards, and the emergency room. Diagnostic errors harm patients and cost the health care system. Among malpractice claims between 1986 and 2010, diagnostic errors accounted for the largest number of claims.2 Diagnostic errors most often led to death and permanent injury and ...
Source: Neurology - April 10, 2017 Category: Neurology Authors: Batra, A., Henderson, G. V. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Clinical trials Systematic review/meta analysis, Infarction, Subarachnoid hemorrhage EDITORIALS Source Type: research

The need for a population-based, dose optimization study for recombinant tissue plasminogen activator in acute ischemic stroke: A study from a tertiary care teaching hospital from South India
Conclusion: There is a need for a properly randomized, dose optimization study of i.v rt-PA in the Indian subcontinent.
Source: Annals of Indian Academy of Neurology - February 8, 2017 Category: Neurology Authors: Siju V Abraham Fazil Thaha S Vimal Krishnan Athulya Shajan Jayaraj Mymbilly Balakrishnan Babu Urumese Palatty Source Type: research

Interaction of incidental microbleeds and prior use of antithrombotics with early hemorrhagic transformation: Causative or protective ?
Conclusion: Presence of incidental CMBs was not associated with increased risk for early HT of an ischemic stroke. Interestingly, the prior intake of antiplatelets was found to be protective against HT of ischemic stroke.
Source: Annals of Indian Academy of Neurology - November 21, 2016 Category: Neurology Authors: Konark Malhotra Monica Khunger Bichun Ouyang David S Liebeskind Yousef M Mohammad Source Type: research

Factors influencing nonadministration of thrombolytic therapy in early arrival strokes in a university hospital in Hyderabad, India
Conclusion: One-fourth of early ischemic stroke patients in our study were not thrombolyzed even though they arrived within the window period. The majority of the reasons for nonadministration of thrombolysis were potentially preventable, such as nonaffordability, intrahospital delay, and nonavailability of newer endovascular interventions.
Source: Annals of Indian Academy of Neurology - July 24, 2016 Category: Neurology Authors: Lalitha Pidaparthi Anitha Kotha Venkat Reddy Aleti Abhijeet Kumar Kohat Mridula R Kandadai Suryaprabha Turaga Jabeen A Shaik Suvarna Alladi Meena A Kanikannan Borgohain Rupam Subhash Kaul Source Type: research

Fruit may be good for you, but don’t ditch the statins
Conclusion The study adds to evidence that fresh fruit is likely to be good for our cardiovascular health, although we can't be sure from this study that it definitely prevents deaths, heart attacks or strokes. Observational studies cannot prove that one factor causes another, even when they are as big as this study, because other unmeasured factors could be responsible for the results. In this case, a major potential confounder that the researchers failed to take into account was whether the participants were taking any medication – they only excluded people taking blood pressure tablets. The link with statins, made by ...
Source: NHS News Feed - April 7, 2016 Category: Consumer Health News Tags: Food/diet Heart/lungs Source Type: news

SRF/MRTF depletion provokes hemorrhagic stroke Cell Biology
Intracerebral hemorrhagic stroke and vascular dementia are age- and hypertension-associated manifestations of human cerebral small vessel disease (SVD). Cerebral microvessels are formed by endothelial cells (ECs), which are connected through tight junctions, adherens junctions, and stabilizing basement membrane structures. These endothelial connections ensure both vessel stability and blood–brain barrier (BBB)...
Source: Proceedings of the National Academy of Sciences - August 11, 2015 Category: Science Authors: Weinl, C., Castaneda Vega, S., Riehle, H., Stritt, C., Calaminus, C., Wolburg, H., Mauel, S., Breithaupt, A., Gruber, A. D., Wasylyk, B., Olson, E. N., Adams, R. H., Pichler, B. J., Nordheim, A. Tags: Biological Sciences Source Type: research

Pages: 1  2  3  4  5  6