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Impact of alcohol control policy on hemorrhagic and ischemic stroke mortality rates in Lithuania: An interrupted time series analysis
This study aimed to test the impact of three major Lithuanian alcohol control policies implemented in 2008, 2017 and 2018 on sex- and stroke subtype-specific mortality rates, among individuals 15+ years-old. Joinpoint regression analyses were performed for each sex- and stroke subtype-specific group to identify timepoints corresponding with significant changes in mortality rate trends. To estimate the impact of each policy, interrupted time series analyses using a generalized additive mixed model were performed on monthly sex- and stroke subtype-specific age-standardized mortality rates from January 2001-December 2018. Sig...
Source: Adicciones - March 28, 2023 Category: Addiction Authors: Kawon Victoria Kim J ürgen Rehm Xinyang Feng Huan Jiang Jakob Manthey Ri čardas Radišauskas Mindaugas Štelemėkas Alexander Tran Anush Zafar Shannon Lange Source Type: research

Prenatal alcohol exposure exacerbates acute sensorimotor deficits and impedes long-term behavioral recovery resulting from adult-onset cerebrovascular ischemic stroke
CONCLUSIONS: Our data indicate that PAE contributes to adverse effects on brain health and to decreased resiliency to a common adult-onset neurovascular disease.PMID:36203340 | DOI:10.1111/acer.14952
Source: Alcoholism, Clinical and Experimental Research - October 7, 2022 Category: Addiction Authors: Shameena Bake David A Hurst Rajesh C Miranda Farida Sohrabji Source Type: research

Cannabis Use and Stroke: Does a Risk Exist?
Conclusions: In people with cannabis use, the prevalence of ischemic stroke and hemorrhagic stroke was 1.2% and 0.3%, respectively, higher than the prevalence of people without use (0.8% and 0.2%). There is insufficient information on timing, exposure, duration, and dose-responsive relationship.
Source: Journal of Addiction Medicine - March 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Hospital-based Buprenorphine/Naloxone Initiation in a Patient With Limited Communication Abilities: A Case Report
North America's opioid crisis highlights the profound need for low-barrier access to opioid agonist therapy (OAT) for the treatment of opioid use disorder (OUD). This case describes a 33-year-old female with a history of opioid and stimulant use disorder admitted to hospital after a left middle cerebral artery ischemic stroke with resulting aphasia. After medical stabilization, she consented to buprenorphine/naloxone through limited verbal and written communication. After 14 days of titration, she was stabilized on 14 to 3.5 milligrams of buprenorphine/naloxone daily. Buprenorphine/naloxone initiation and titration is pati...
Source: Journal of Addiction Medicine - November 1, 2021 Category: Addiction Tags: Case Reports Source Type: research

Multiple Cerebral Infarcts in a Young Patient Associated With Marijuana Use
Cerebrovascular events associated with marijuana use have been reported previously. This association is plausible, but not well-established yet. A 14-year-old girl, long-term heavy cannabis user, presented with generalized tonic-clonic seizures and decreased level of consciousness a few hours after smoking cannabis. Brain magnetic resonance imaging showed multiple areas of acute, subacute and chronic ischemic lesions in the left frontal lobe, basal ganglia, and corpus callosum. History of other illicit drug use and other known causes of stroke were ruled out. Cannabis might cause stroke through direct effects on the cerebr...
Source: Journal of Addiction Medicine - September 1, 2017 Category: Addiction Tags: Case Reports Source Type: research

Risk of stroke in prescription and other amphetamine ‐type stimulants use: A systematic review
Conclusions. This is the first systematic review on ATS and stroke. Limited epidemiological evidence suggests that ATS use increases stroke risk. Possible disparities in ATS effect across stroke type and higher effect in women deserve further clarification. Studies on non‐medical ATS use should be a priority. [Indave BI, Sordo L, Bravo MJ, Sarasa‐Renedo A, Fernández‐Balbuena S, De la Fuente L, Sonego M, Barrio G. Risk of stroke in prescription and other amphetamine‐type stimulants use: A systematic review. Drug Alcohol Rev 2017;00:000–000]
Source: Drug and Alcohol Review - May 8, 2017 Category: Addiction Authors: Blanca Iciar Indave, Luis Sordo, Mar ía José Bravo, Ana Sarasa‐Renedo, Sonia Fernández‐Balbuena, Luis De la Fuente, Michela Sonego, Gregorio Barrio Tags: Comprehensive Review Source Type: research

Fetal Alcohol Exposure Alters Blood Flow and Neurological Responses to Transient Cerebral Ischemia in Adult Mice
ConclusionsOur data collectively show that PAE adult mice exhibit a persistent, long‐term loss of cranially directed blood flow, and decreased capacity to compensate for brain trauma due to acute‐onset adult diseases like ischemic stroke. Our study assessed long‐term consequences of prenatal alcohol exposure (PAE) on blood flow and on behavioral outcomes following unilateral middle cerebral artery occlusion (MCAo)‐induced transient ischemic stroke in adults. PAE resulted in a significant age‐related decrease in blood acceleration in mature adult and middle‐aged mice, specifically in the carotid artery. Followi...
Source: Alcoholism: Clinical and Experimental Research - December 16, 2016 Category: Addiction Authors: Shameena Bake, Rachel Gardner, Joseph D. Tingling, Rajesh C. Miranda, Farida Sohrabji Tags: Original Article Source Type: research

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