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Condition: Ischemic Stroke
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Total 1110 results found since Jan 2013.

Indications for transfusion in the management of sickle cell disease
Hematology Am Soc Hematol Educ Program. 2021 Dec 10;2021(1):696-703. doi: 10.1182/hematology.2021000307.ABSTRACTThe transfusion of red blood cells (RBCs) is a crucial treatment for sickle cell disease (SCD). While often beneficial, the frequent use of transfusions is associated with numerous complications. Transfusions should be offered with specific guidelines in mind. Here we present updates to the indications for transfusion of RBCs in SCD. We review recent publications and include expert perspectives from hematology and transfusion medicine. For some clinical indications, such as ischemic stroke, the role of transfusio...
Source: Hematology ASH Education Program - December 10, 2021 Category: Hematology Authors: Hyojeong Han Lisa Hensch Ven ée N Tubman Source Type: research

Mitochondrial DNA Copy Number as a Marker and Mediator of Stroke Prognosis: Observational and Mendelian Randomization Analyses
CONCLUSIONS: Buffy coat mtDNA-CN is a novel and robust marker of post-stroke prognosis that may also be a causal determinant of post-stroke outcomes.CLASSIFICATION OF EVIDENCE: This study provides class II evidence that low buffy coat mtDNA-CN (>1-standard deviation) was associated with worse baseline severity and 1-month outcomes in patients with ischemic or hemorrhagic stroke.PMID:34880091 | DOI:10.1212/WNL.0000000000013165
Source: Atherosclerosis - December 9, 2021 Category: Cardiology Authors: Michael Robert Chong Sukrit Narula Robert Morton Conor Judge Loubna Akhabir Nathan Cawte Nazia Pathan Ricky Lali Pedrum Mohammadi-Shemirani Ashkan Shoamanesh Martin O'Donnell Salim Yusuf Peter Langhorne Guillaume Pare Source Type: research

Relationship Between Lipoprotein (a) Lp(a) and Cognition in Different Ischemic Stroke Subtypes
Conclusion: Higher Lp(a) level was associated with cognitive impairment and less improvement of cognition in patients after AIS or TIA with large-artery atherosclerosis subtype.
Source: Frontiers in Neurology - December 3, 2021 Category: Neurology Source Type: research

Prestroke physical activity and outcomes after intracerebral haemorrhage in comparison to ischaemic stroke: protocol for a matched cohort study (part of PAPSIGOT)
Introduction Piling evidence suggests that a higher level of prestroke physical activity can decrease stroke severity, and reduce the risk of poststroke mortality. However, prior studies have only included ischaemic stroke cases, or a majority of such. We aim to investigate how premorbid physical activity influences admission stroke severity and poststroke mortality in patients with intracerebral haemorrhage, compared with ischaemic stroke. A prespecified analysis plan counteract some inherent biases in observational studies, and promotes transparency. Methods and analysis This is a statistical analysis protocol for a mat...
Source: BMJ Open - November 19, 2021 Category: General Medicine Authors: Viktorisson, A., Buvarp, D., Sunnerhagen, K. S. Tags: Open access, Neurology Source Type: research

COVID-19 mental health impact among children with early brain injury and associated conditions
This study describes the impact of COVID-19 among a clinical research sample of children with early brain injury and associated conditions. Between March 2020 and March 2021, 64 children and their parents participated. Children ranged in age between 3 and 14 years (M = 6 years, 3 months; SD = 2 years, 4 months) with a range of diagnoses (i.e., neonatal stroke, hypoxic ischemic encephalopathy (HIE), congenital heart disease (CHD) and preterm birth (<32 weeks)). The abbreviated CoRonavIrus Health Impact Survey (CRISIS) was completed by parents as part of their child's routine intake for neuropsychological services. Questi...
Source: Child Neuropsychology - November 15, 2021 Category: Child Development Authors: Tricia S Williams Angela Deotto Samantha D Roberts Meghan K Ford Naddley D ésiré Sarah Cunningham Source Type: research