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Specialty: Neuroscience
Condition: Epilepsy
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Total 161 results found since Jan 2013.
Targeting the neurological comorbidities of multiple sclerosis: the beneficial effects of VIP and PACAP neuropeptides
J Integr Neurosci. 2022 Jan 28;21(1):33. doi: 10.31083/j.jin2101033.ABSTRACTVasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are two widely expressed neuropeptides with important immunomodulatory and neuroprotective properties in the central nervous system (CNS). Both VIP and PACAP have been implicated in several neurological diseases and have shown favourable effects in different animal models of multiple sclerosis (MS). MS is a chronic inflammatory and neurodegenerative disease of the CNS affecting over 2.5 million people worldwide. The disease is characterised by extensi...
Source: Journal of Integrative Neuroscience - February 15, 2022 Category: Neuroscience Authors: Margo I Jansen Sarah Thomas Broome Alessandro Castorina Source Type: research
Ying Yang 1 engagement in brain pathology
AbstractHerein, we discuss data concerning the involvement of transcription factor Yin Yang 1 (YY1) in the development of brain diseases, highlighting mechanisms of its pathological actions. YY1 plays an important role in the developmental and adult pathology of the nervous system. YY1 is essential for neurulation as well as maintenance and differentiation of neuronal progenitor cells and oligodendrocytes regulating both neural and glial tissues of the brain. Lack of a YY1 gene causes many developmental abnormalities and anatomical malformations of the central nervous system (CNS). Once dysregulated, YY1 exerts multiple ne...
Source: Journal of Neurochemistry - February 24, 2022 Category: Neuroscience Authors: Sylwia Pabian ‐Jewuła,
Aneta Bragiel‐Pieczonka,
Marcin Rylski Tags: SYSTEMATIC REVIEW Source Type: research
Targeting the neurological comorbidities of multiple sclerosis: the beneficial effects of VIP and PACAP neuropeptides
J Integr Neurosci. 2022 Jan 28;21(1):33. doi: 10.31083/j.jin2101033.ABSTRACTVasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are two widely expressed neuropeptides with important immunomodulatory and neuroprotective properties in the central nervous system (CNS). Both VIP and PACAP have been implicated in several neurological diseases and have shown favourable effects in different animal models of multiple sclerosis (MS). MS is a chronic inflammatory and neurodegenerative disease of the CNS affecting over 2.5 million people worldwide. The disease is characterised by extensi...
Source: Journal of Integrative Neuroscience - February 15, 2022 Category: Neuroscience Authors: Margo I Jansen Sarah Thomas Broome Alessandro Castorina Source Type: research
Epilepsia Partialis Continua a Clinical Feature of a Missense Variant in the ADCK3 Gene and Poor Response to Therapy
ConclusionsA novel homozygous missense variant [NM_020247.5: c.814G>T; (p.Gly272Cys)] was identified within theADCK3 gene, which is the first mutation in this gene in the Iranian population. Bioinformatics analysis showed this variant is damaging. Based on our patient, clinicians should consider genetic testing earlier to instant diagnosis and satisfactory treatment based on exact etiology to prevent further neurologic sequelae.
Source: Journal of Molecular Neuroscience - March 11, 2022 Category: Neuroscience Source Type: research
