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< em > Angelica gigas < /em > : Signature Compounds, < em > In Vivo < /em > Anticancer, Analgesic, Neuroprotective and Other Activities, and the Clinical Translation Challenges
Am J Chin Med. 2022 Jul 23:1-53. doi: 10.1142/S0192415X2250063X. Online ahead of print.ABSTRACTAngelica gigas Nakai (AGN) root is a medicinal herbal widely used in traditional medicine in Korea. AGN root ethanolic extract dietary supplements are marketed in the United States for memory health and pain management. We comprehensively reviewed the anticancer, analgesic, pro-memory and other bio-activities of AGN extract and its signature phytochemicals decursin, decursinol angelate, and decursinol a decade ago in 2012 and updated their anticancer activities in 2015. In the last decade, significant progress has been made for u...
Source: The American Journal of Chinese Medicine - July 25, 2022 Category: Complementary Medicine Authors: Junxuan L ü Cheng Jiang Todd D Schell Monika Joshi Jay D Raman Chengguo Xing Source Type: research

Gastrodin and Vascular Dementia: Advances and Current Perspectives
Evid Based Complement Alternat Med. 2022 Apr 12;2022:2563934. doi: 10.1155/2022/2563934. eCollection 2022.ABSTRACTGastrodia elata, a traditional Chinese medicine, has been widely used since ancient times to treat diseases such as dizziness, epilepsy, stroke, and memory loss. Gastrodin, one of the active components of Gastrodia elata, has been used in the treatment of migraine, epilepsy, Parkinson's disease, dementia, and depression in recent years. It can improve cognitive function and related neuropsychiatric symptoms through various effects and is considered as a promising treatment for dementia. Vascular dementia is a k...
Source: Evidence-based Complementary and Alternative Medicine - April 25, 2022 Category: Complementary Medicine Authors: Chujun Deng Huize Chen Zeyu Meng Shengxi Meng Source Type: research

Efficacy of Acupuncture Treatment for Incidence of Poststroke Comorbidities: A Systematic Review and Meta-Analysis of Nationalized Cohort Studies
Evid Based Complement Alternat Med. 2022 Feb 1;2022:3919866. doi: 10.1155/2022/3919866. eCollection 2022.ABSTRACTAcupuncture has been applied as a complementary therapy in stroke survivors worldwide and approved to be beneficial to stroke recovery. However, there is little medical evidence regarding the association between acupuncture and the risk of poststroke comorbidities. We reviewed big data studies from the Taiwan National Health Insurance Research Database to investigate the risk of poststroke comorbidities after acupuncture treatment in a real-world situation. Ten English (PubMed, Embase, Medline, Cochrane, Alt Hea...
Source: Evidence-based Complementary and Alternative Medicine - February 14, 2022 Category: Complementary Medicine Authors: Li-Kung Wu Chung-Shan Hung Yen-Lun Kung Zhong-Kui Chen Shinn-Zong Lin Jaung-Geng Lin Tsung-Jung Ho Source Type: research

A Study to Decipher the Potential Effects of Butylphthalide against Central Nervous System Diseases Based on Network Pharmacology and Molecular Docking Integration Strategy
CONCLUSIONS: Our study proposed a drug-target-disease integrated method to predict the drug repurposing potentials to associated diseases by application of NP and MD, which could be an attractive alternative to facilitate the development of CNS disease therapies. NBP may be promising and showed potentials to be repurposed for treatments for AD, epilepsy, ALS, and depression, and further investigations are warranted to be carefully designed and conducted.PMID:34035826 | PMC:PMC8116153 | DOI:10.1155/2021/6694698
Source: Evidence-based Complementary and Alternative Medicine - May 26, 2021 Category: Complementary Medicine Authors: Qinqin Zhao Bei Zheng Pinpin Feng Xiang Li Source Type: research

Signal Transduction Pathways of Acupuncture for Treating Some Nervous System Diseases.
Authors: Lai HC, Chang QY, Hsieh CL Abstract In this article, we review signal transduction pathways through which acupuncture treats nervous system diseases. We electronically searched the databases, including PubMed, MEDLINE, clinical Key, the Cochrane Library, and the China National Knowledge Infrastructure from their inception to December 2018 using the following MeSH headings and keywords alone or in varied combination: acupuncture, molecular, signal transduction, genetic, cerebral ischemic injury, cerebral hemorrhagic injury, stroke, epilepsy, seizure, depression, Alzheimer's disease, dementia, vascular demen...
Source: Evidence-based Complementary and Alternative Medicine - August 6, 2019 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research