Signal Transduction Pathways of Acupuncture for Treating Some Nervous System Diseases.

Signal Transduction Pathways of Acupuncture for Treating Some Nervous System Diseases. Evid Based Complement Alternat Med. 2019;2019:2909632 Authors: Lai HC, Chang QY, Hsieh CL Abstract In this article, we review signal transduction pathways through which acupuncture treats nervous system diseases. We electronically searched the databases, including PubMed, MEDLINE, clinical Key, the Cochrane Library, and the China National Knowledge Infrastructure from their inception to December 2018 using the following MeSH headings and keywords alone or in varied combination: acupuncture, molecular, signal transduction, genetic, cerebral ischemic injury, cerebral hemorrhagic injury, stroke, epilepsy, seizure, depression, Alzheimer's disease, dementia, vascular dementia, and Parkinson's disease. Acupuncture treats nervous system diseases by increasing the brain-derived neurotrophic factor level and involves multiple signal pathways, including p38 MAPKs, Raf/MAPK/ERK 1/2, TLR4/ERK, PI3K/AKT, AC/cAMP/PKA, ASK1-JNK/p38, and downstream CREB, JNK, m-TOR, NF-κB, and Bcl-2/Bax balance. Acupuncture affects synaptic plasticity, causes an increase in neurotrophic factors, and results in neuroprotection, cell proliferation, antiapoptosis, antioxidant activity, anti-inflammation, and maintenance of the blood-brain barrier. PMID: 31379957 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Related Links:

The aim of this study was to examine the associations between self-harm and suicidal behavior in indigenous Sami and non-Sami adolescents and mental health and social outcomes in young adulthood. Data were obtained by linking the Norwegian Patient Registry...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
INTRODUCTION: Depression is a highly prevalent problem in adolescence, with great clinical and social relevance. Recent models of psychopathology in childhood and adolescence underscore that the relationships between stress, cognitive vulnerabilities, and ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
INTRODUCTION: Interpersonal trust behavior is an important target for the identification and treatment of psychiatric disorders with interpersonal dysfunction. Adolescent depression is a highly interpersonal disorder marked by impaired social interactions....
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
This study investigated the associations between gratitude, measures of well-being, and indicators of psychological distress (depression and negative emotion) among South African university students. Data were collected from 198 first-year university stude...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Despite the advantages of international study -- to the student, the university, and the local community -- studies have reported an increased risk of stress-related psychological problems in international students. We surveyed 384 Asian international stud...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
This study explored the contexts in which adolescents report perceptions of being a burden on others, via a mixed-methods approach, to inform the development of interventions targeting perceived burdensomeness as a risk factor for suicide ide...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Drawing from Race-Based Traumatic Stress theory, the present study examined whether traumatic stress and depressive symptoms differentially help explain the relation between racial/ethnic discrimination and suicidal ideation across gender and racial/ethnic...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Hopelessness is a well-established risk factor for suicidal ideation. Recent research has indicated that hopelessness can be split into two subsets: pessimism (PESS) and lack of optimism (LOO) and that LOO is more salient of the two in predicting suicide i...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
INTRODUCTION: The positive effects of expressive writing on both mental and physical health are well documented. However, expressive writing may have the potential to activate negative schemas and facilitate rumination in those at high cognitive risk for d...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
The aim of this study was to analyze the predictive risk factors for self-harm in adolescents with and without suicidal ideation. 600 adolescents answered a questionnaire about self-harm and suicidal behaviors. A logistic regression analysis was conducted....
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
More News: Acupuncture | Alternative and Complementary Therapies | Alzheimer's | Antidoxidants | Brain | China Health | Complementary Medicine | Databases & Libraries | Dementia | Depression | Epilepsy | Genetics | Hemorrhagic Stroke | Ischemic Stroke | Neurology | Parkinson's Disease | Stroke