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Vaccination: Malaria Vaccine
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Total 77 results found since Jan 2013.
Potential drugs in COVID-19 management
Curr Med Chem. 2023 Jul 17. doi: 10.2174/0929867331666230717154101. Online ahead of print.ABSTRACTThe SARS-CoV-2 virus first emerged in China in December 2019 and quickly spread worldwide. Despite the absence of a vaccination or authorized drug specifically developed to combat this infection, certain medications recommended for other diseases have shown potential effectiveness in treating COVID-19, although without definitive confirmation. This review aims to evaluate the existing literature on the efficacy of these medications against COVID-19. The review encompasses various potential treatments, including antiviral medic...
Source: Current Medicinal Chemistry - July 18, 2023 Category: Chemistry Authors: Amin Gasmi Sadaf Noor Alain Menzel Nataliia Khanyk Yuliya Semenova Roman Lysiuk Nataliya Beley Lidiia Bolibrukh Asma Gasmi Benahmed Olha Storchylo Geir Bj ørklund Source Type: research
Clinical evaluation of commercial SARS-CoV-2 serological assays in a malaria endemic setting
J Immunol Methods. 2023 May 11:113488. doi: 10.1016/j.jim.2023.113488. Online ahead of print.ABSTRACTThe levels of immune response to SARS-CoV-2 infection or vaccination are poorly understood in African populations and is complicated by cross-reactivity to endemic pathogens as well as differences in host responsiveness. To begin to determine the best approach to minimize false positive antibody levels to SARS-CoV-2 in an African population, we evaluated three commercial assays, namely Bio-Rad Platelia SARS-CoV-2 Total Antibody (Platelia), Quanterix Simoa Semi-Quantitative SARS-CoV-2 IgG Antibody Test (anti-Spike), and the ...
Source: Journal of Immunological Methods - May 13, 2023 Category: Allergy & Immunology Authors: Djeneba Dabitao Kathryn Shaw-Saliba Drissa S Konate Helene C Highbarger Perrine Lallemand Ibrahim Sanogo Tauseef Rehman Mamadou Wague Nadie Coulibaly Bourahima Kone Bocar Baya Seidina A S Diakite Seydou Samake Esther Akpa Moctar Tounkara Sylvain Laverdure Source Type: research
Performance of SARS-CoV-2 Antigens in a Multiplex Bead Assay for Integrated Serological Surveillance of Neglected Tropical and Other Diseases
Am J Trop Med Hyg. 2022 Jun 27:tpmd220078. doi: 10.4269/ajtmh.22-0078. Online ahead of print.ABSTRACTSerosurveillance can provide estimates of population-level exposure to infectious pathogens and has been used extensively during the COVID-19 pandemic. Simultaneous, serological testing for multiple pathogens can be done using bead-based immunoassays to add value to disease-specific serosurveys. We conducted a validation of four SARS-CoV-2 antigens-full-length spike protein, two receptor binding domain proteins, and the nucleocapsid protein-on our existing multiplex bead assay (MBA) for enteric diseases, malaria, and vaccin...
Source: Am J Trop Med Hyg - July 27, 2022 Category: Infectious Diseases Authors: Sarah Gwyn Ado Abubakar Oluwaseun Akinmulero Eric Bergeron Ugboaja Nkechi Blessing Jasmine Chaitram Melissa M Coughlin Ayuba B Dawurung Felicia Nwatu Dickson Mudiaga Esiekpe Erasogie Evbuomwan Stacie M Greby Nnaemeka C Iriemenam Markus H Kainulainen Thoma Source Type: research
Synthesis, spectral characterization, crystal structure and computational investigation of 2-formyl-6-methoxy-3-carbethoxy quinoline as potential SARS-CoV inhibitor
J Phys Chem Solids. 2022 Nov;170:110886. doi: 10.1016/j.jpcs.2022.110886. Epub 2022 Jul 12.ABSTRACTThe recent COVID-19 outbreak caused by the novel coronavirus SARS-CoV-2 has an immense impact on global health and economy. Although vaccines are being used, urgent need of drugs based on natural products with high efficacy and safety is a pressing priority. Quinoline alkaloids are well known for their therapeutic action against malaria; initially, it was tried against Coronaviruses. It is a basic vital scaffold to design drugs with required biological and pharmacological activities. In this present study, a new quinoline com...
Source: Health Physics - July 18, 2022 Category: Physics Authors: A Franklin Ebenazer M Saravanabhavan K S Ramesh Shabbir Muhammad Abdullah G Al-Sehemi N Sampathkumar Source Type: research
