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Quantification of Aerosol Particle Concentrations During Endoscopic Sinonasal Surgery in the Operating Room.
CONCLUSION: Drilling and microdebrider use during endonasal surgery in a standard operating room is associated with a significant increase in airborne particle concentrations. Fortunately, this increase in aerosol concentration is localized to the area of the operating surgeon, with no detectable increase in aerosol particles at other OR positions. PMID: 33012174 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - October 3, 2020 Category: ENT & OMF Authors: Murr A, Lenze NR, Brown WC, Gelpi MW, Ebert CS, Senior BA, Thorp BD, Zanation AM, Kimple AJ Tags: Am J Rhinol Allergy Source Type: research

Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice
Conclusions: These results suggest that strain-specific changes in chromatin and transcription in response to chemical exposure lead to a “compensation” for underlying genetic-driven interindividual differences in the baseline chromatin and transcriptional state. This work represents an example of how chemical and environmental exposures can be evaluated to better understand gene-by-environment interactions, and it demonstrates the important role of chromatin response in transcriptomic changes and, potentially, in deleterious effects of exposure. https://doi.org/10.1289/EHP1937 Received: 21 March 2017 Revis...
Source: EHP Research - October 17, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research