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The dietary transition and its association with cardiometabolic mortality among Chinese adults, 1982–2012: a cross-sectional population-based study
Publication date: Available online 10 May 2019Source: The Lancet Diabetes & EndocrinologyAuthor(s): Yuna He, Yanping Li, Xiaoguang Yang, Elena C Hemler, Yuehui Fang, Liyun Zhao, Jian Zhang, Zhenyu Yang, Zhu Wang, Li He, Jing Sun, Dong D Wang, Jingzhong Wang, Jianhua Piao, Xiaofeng Liang, Gangqiang Ding, Frank B HuSummaryBackgroundFew studies have used nationally representative data to describe dietary trends and the related cardiometabolic mortality burden in China. Thus, we aimed to characterise the trends in disease-related dietary factors as well as their associated disease burden among Chinese adults from 1982 to 2012....
Source: The Lancet Diabetes and Endocrinology - May 12, 2019 Category: Endocrinology Source Type: research

Treatment of diabetes mellitus has borne much fruit in the prevention of cardiovascular disease
ABSTRACTCardiovascular (CV) disease is the most alarming complication of diabetes mellitus (DM), and a strategy aiming at CV event prevention in DM has long been debated. Large landmark clinical trials have shown CV benefits of intensive glycemic control as a “legacy effect” in newly diagnosed type 2 DM (T2DM). In contrast, we have learned that excessive intervention aimed at strong glycemic control could cause unexpected CV death in patients who are resistant to treatments against hyperglycemia. It has also been shown that the comprehensive multifac torial intervention for CV risk factors that was advocated in the cur...
Source: Journal of Diabetes Investigation - May 31, 2022 Category: Endocrinology Authors: Hiroaki Yagyu, Hitoshi Shimano Tags: REVIEW ARTICLE Source Type: research

The Potential Role of Naringin and Naringenin as Nutraceuticals against Metabolic Syndrome
Endocr Metab Immune Disord Drug Targets. 2022 Aug 27. doi: 10.2174/1871530322666220827141203. Online ahead of print.ABSTRACTMetabolic syndrome, an increasing problem in western society, is a cluster of conditions which affects cardiovascular health, lipid and glucose management, increasing the risk of heart diseases, stroke and diabetes. Bioactive flavonoids are a great resource of compounds with proved anti-inflammatory activities. Naringin, a natural flavanone found in citrus fruits, and its aglycone have demonstrated to ameliorate obesity, dyslipidemia, and insulin resistance in animal models. The principal mechanisms b...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 31, 2022 Category: Endocrinology Authors: Luca Massaro Anna Raguzzini Paola Aiello D ébora Villaño Valencia Source Type: research