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Condition: Dermatitis
Therapy: Corticosteroid Therapy

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Total 1736 results found since Jan 2013.

Identification and structural characterization of major stress degradation products of halcinonide by liquid chromatography-high-resolution mass spectrometry
Biomed Chromatogr. 2023 Aug 31:e5730. doi: 10.1002/bmc.5730. Online ahead of print.ABSTRACTHalcinonide is a topical corticosteroid approved by the US Food and Drug Administration (FDA), known for its anti-inflammatory and antipruritic properties. The therapeutic benefits of halcinonide have rendered it an effective treatment regimen for various dermatological conditions such as psoriasis, dermatitis, and eczema. However, stability of the drug substance is a prerequisite in determining the therapeutic efficacy and plays a crucial role during formulation development and long-term storage. As corticosteroids are highly suscep...
Source: Biomedical Chromatography : BMC - August 31, 2023 Category: Biomedical Science Authors: Shivraj Giri Devendra Badgujar Sree Teja Paritala Nitish Sharma Source Type: research

Safety and Efficacy of Tralokinumab in Older Adults With Moderate-to-Severe Atopic Dermatitis: A Secondary Analysis
CONCLUSION AND RELEVANCE: The results of this post hoc analysis suggest that tralokinumab is well tolerated and efficacious in patients 65 years or older with moderate-to-severe AD.PMID:37610789 | DOI:10.1001/jamadermatol.2023.2626
Source: Herpes - August 23, 2023 Category: Infectious Diseases Authors: Joseph F Merola Daniel C Butler Thomas Mark Shannon Schneider Yestle Kim Katrina Abuabara Source Type: research

Dupilumab significantly improves sleep in adults with atopic dermatitis: results from the 12-week placebo-controlled period of the 24-week phase 4 randomized double-blinded placebo-controlled DUPISTAD study
CONCLUSIONS: Dupilumab significantly improved sleep quality and perception of sleep continuity, itch, metrics of AD severity, and QoL in adults with moderate-to-severe AD, with an acceptable safety profile versus placebo.TRIAL REGISTRATION NUMBER: ClinicalTrials.gov: NCT04033367.PMID:37562034 | DOI:10.1093/bjd/ljad284
Source: The British Journal of Dermatology - August 10, 2023 Category: Dermatology Authors: Joseph F Merola Albert S Chiou Emmanuel During Antonio Costanzo Peter Foley Amani Alfalasi Shaila Gogate Andreas Pinter Roni Dodiuk-Gad Dagmar Simon Marie Tauber Richard Weller Jose-Juan Pereyra-Rodriguez Marius Ardeleanu Jiangming Wu Zafer E Ozturk Source Type: research

The Anti-Inflammatory and Skin Barrier Function Recovery Effects of < em > Schisandra chinensis < /em > in Mice with Atopic Dermatitis
Conclusions: These results suggest that S. chinensis can be used as an alternative to external corticosteroids and that its anti-inflammatory and skin barrier dysfunction-restoring effects are related to the downregulation of pro-inflammatory cytokines and chemokines, such as TNF-α, IL-4, IL-6, IL-8, and TSLP.PMID:37512164 | PMC:PMC10385087 | DOI:10.3390/medicina59071353
Source: Medicina (Kaunas) - July 29, 2023 Category: Universities & Medical Training Authors: Yoorae Son Wonjin Yang Sangjun Park Jinkyu Yang Soyeon Kim Ji-Hyo Lyu Hyungwoo Kim Source Type: research