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Analysis of risk factors related to acute radiation dermatitis in breast cancer patients during radiotherapy
Conclusions: ARD in response to postoperative radiotherapy in patients with breast cancer is common and mild. Clinicians and patients need to cultivate awareness of the potential risk factors involved and then intervene to alleviate skin reactions and improve the quality of life.
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Di Liu Zhewen Zheng Shuyuan Zhang Chunmei Zhu Hongyan Zhang Yunfeng Zhou Source Type: research

What Are Causes of Childhood Interstital Lung Disease?
Discussion Interstitial lung disease in children (chILD) is less understood than adult interstitial lung disease (ILD) and is rare. Prevalence is ~ 0.13 to 16.2 per 100,000 children under age 17 years. chILD is an general term for respiratory disorders that are heterogeneous, chronic and impair lung function. While some define diffuse parenchymal lung disease (DPLD) separately, the term ILD usually encompases DPLD. chILD has variable definitions and is “usually diagnosed if three of the following features are present: 1) respiratory symptoms (cough, rapid and/or difficult breathing, and exercise intolerance), 2) res...
Source: PediatricEducation.org - August 1, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Human Gut-Associated Natural Killer Cells in Health and Disease
Alessandro Poggi1*, Roberto Benelli2, Roberta Venè1, Delfina Costa1, Nicoletta Ferrari1, Francesca Tosetti1 and Maria Raffaella Zocchi3 1Molecular Oncology and Angiogenesis Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy 2Immunology Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy 3Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy It is well established that natural killer (NK) cells are involved in both innate and adaptive immunity. Indeed, they can recognize molecules induced at the cell surface by stress signals...
Source: Frontiers in Immunology - May 2, 2019 Category: Allergy & Immunology Source Type: research

XXIV World Allergy Congress 2015
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendr...
Source: World Allergy Organization Journal - April 18, 2016 Category: Allergy & Immunology Source Type: research

Answers to Dermatophile
Answers From the questions on page 185. Answer to question 1 B—Langerhans cell histiocytosis (LCH): Abnormal clonal proliferation of histiocytes, resembling Langerhans cells, and its accumulation in different tissues and organs. LCH exhibits heterogeneous clinical pictures and evolution—it varies from the isolated cutaneous lesion with spontaneous resolution to severe cases involving the liver, spleen, lung and haematopoietic system.1 The most common skin lesion is similar to seborrhoeic dermatitis, but exhibits petechiae and purpura, and affects the scalp, eyebrows, ears and intertriginous areas.2 Seborrhoeic-...
Source: Archives of Disease in Childhood - Education and Practice - July 17, 2015 Category: Pediatrics Authors: Carvalho, V. O., Robl, R., Uber, M., Abagge, K. T., Marinoni, L. P., Presa, J. G. L. Tags: Oncology, Surgery, Immunology (including allergy), Drugs: infectious diseases, Child health, Pathology, Radiology, Interstitial lung disease, Dermatology, Surgical diagnostic tests, Clinical diagnostic tests, Drugs: endocrine system Dermatophile Source Type: research

Cutaneous drug eruptions associated with the use of new oncological drugs.
Authors: Belloni B, Schönewolf N, Rozati S, Goldinger SM, Dummer R Abstract There is a variety of adverse effects and toxicities of newer and older chemotherapeutic agents which emerge in the skin, mucosa and adnexa. Common skin reactions while undergoing chemotherapy include alopecia, changes in skin pigmentation, palmoplantar erythrodysesthesia, nail dystrophies and stomatitis. Extravasation injuries or hypersensitivity reactions may be severe. New oncologic agents have led to the development of different, class-specific cutaneous side effects. Epidermal growth factor receptor (EGFR) inhibitors induce papulopust...
Source: Chemical Immunology and Allergy - December 2, 2014 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research