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Developing an Intervention to Improve the Health Related Quality of Life in Children and Young People With Serious Parental Mental Illness
Conclusion: Young SMILES captures a broad age range and level of need for CAPRI and can be evaluated with quantifiable child-centered outcomes. In line with current policy directives, this is the first UK-based, multi-context intervention to improve QoL in this population. Implementation and referral mechanisms are currently being evaluated in a multi-site feasibility trial. Introduction Children and adolescents living with parental mental illness (CAPRI) are poorly provided for in current social care and educational settings (1, 2). Children and young people (CYP) growing up in families affected by parental mental h...
Source: Frontiers in Psychiatry - April 8, 2019 Category: Psychiatry Source Type: research

Report from the National Institute of Allergy and Infectious Diseases Workshop on “Atopic Dermatitis and the Atopic March: Mechanisms and Interventions”
Atopic dermatitis (AD) affects up to 20% of children world-wide and is an increasing public health problem particularly in developed countries. Although AD in infants and young children can resolve, there is a well-recognized, increased risk of sequential progression from AD to other atopic diseases including food allergy, allergic rhinitis, allergic asthma and allergic rhinoconjunctivitis; a process referred to as the “atopic march”. The mechanisms underlying the development of AD and subsequent progression to other atopic comorbidities, particularly food allergy, are incompletely understood and the subject of intense investigation.
Source: Journal of Allergy and Clinical Immunology - January 9, 2019 Category: Allergy & Immunology Authors: Wendy F. Davidson, Donald Y.M. Leung, Lisa A. Beck, Cecilia M. Berin, Mark Boguniewicz, William W. Busse, Talal A. Chatila, Raif S. Geha, James E. Gern, Emma Guttman-Yassky, Alan D. Irvine, Brian S. Kim, Heidi H. Kong, Gideon Lack, Kari C. Nadeau, Julie S Source Type: research

Hydrolyzed Proteins in Allergy.
Authors: Salvatore S, Vandenplas Y Abstract Hydrolyzed proteins are used worldwide in the therapeutic management of infants with allergic manifestations and have long been proposed as a dietetic measure to prevent allergy in at risk infants. The degree and method of hydrolysis, protein source and non-nitrogen components characterize different hydrolyzed formulas (HFs) and may determine clinical efficacy, tolerance and nutritional effects. Cow's milk (CM)-based HFs are classified as extensively (eHF) or partially HF (pHF) based on the percentage of small peptides. One whey pHF has been shown to reduce atopic dermati...
Source: Nestlee Nutrition Institute Workshop Series - June 25, 2016 Category: Nutrition Tags: Nestle Nutr Inst Workshop Ser Source Type: research

Hydrolyzed Formula for Every Infant?
Authors: Fleischer DM, Venter C, Vandenplas Y Abstract Presently, hydrolyzed formulas (HF) are used primarily in infants that cannot be exclusively breastfed, those with cow's milk allergy and for primary prevention of allergic disease, but HFs are increasingly being used worldwide, begging the question if they may be recommended as the optimal choice for all standard-risk, full-term, non-exclusively breastfed infants. Data regarding the nutritional adequacy of modern-day HFs are scarce and lack long-term data suggesting that growth in infants fed HF versus an intact protein formula (IPF) is different. While human ...
Source: Nestlee Nutrition Institute Workshop Series - June 25, 2016 Category: Nutrition Tags: Nestle Nutr Inst Workshop Ser Source Type: research

Proteins, Peptides and Amino Acids: Role in Infant Nutrition.
In conclusion, proteins provided via breast milk or infant formula are essential components of the infant's diet; therefore, the specific quality, quantity and conformation of proteins are of utmost importance for healthy growth and development. PMID: 27336588 [PubMed - as supplied by publisher]
Source: Nestlee Nutrition Institute Workshop Series - June 25, 2016 Category: Nutrition Tags: Nestle Nutr Inst Workshop Ser Source Type: research

Infant Feeding: Foods, Nutrients and Dietary Strategies to Prevent Allergy.
Authors: Beyer K Abstract Food allergy is a common disease. In recent years, recommendations for the prevention of food allergy have been shifted from avoidance strategies to active oral tolerance induction. Due to evidence from observational studies, it has been suggested that sensitization occurs via the skin especially in children with atopic dermatitis due to skin barrier defects, whereas early oral introduction of the allergenic food(s) will promote tolerance. The current evidence does not justify recommendations about either withholding or encouraging exposure to potentially allergenic food(s) after 4 months ...
Source: Nestlee Nutrition Institute Workshop Series - April 20, 2016 Category: Nutrition Tags: Nestle Nutr Inst Workshop Ser Source Type: research

Preventing atopy and allergic disease.
Authors: Heine RG Abstract Due to the recent exponential increase in food allergies and atopic disorders, effective allergy prevention has become a public health priority in many developed regions. Important preventive strategies include the promotion of breastfeeding and vaginal deliveries, judicious use of perinatal antibiotics, as well as the avoidance of maternal tobacco smoking. Breastfeeding for at least 6 months and introduction of complementary solids from 4-6 months are generally recommended. Complex oligosaccharides in breast milk support the establishment of bifidobacteria in the neonatal gut which stimu...
Source: Nestlee Nutrition Institute Workshop Series - September 24, 2015 Category: Nutrition Tags: Nestle Nutr Inst Workshop Ser Source Type: research