• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

An updated review on prediction and preventive treatment of post-stroke depression
Expert Rev Neurother. 2023 Jul-Dec;23(8):721-739. doi: 10.1080/14737175.2023.2234081. Epub 2023 Jul 10.ABSTRACTINTRODUCTION: Post-stroke depression (PSD), one of the most common complications following stroke, affects approximately one-third of stroke patients and is significantly associated with increased disability and mortality as well as decreased quality of life, which makes it an important public health concern. Treatment of PSD significantly ameliorates depressive symptoms and improves the prognosis of stroke.AREAS COVERED: The authors discuss the critical aspects of the clinical application of prediction and preven...
Source: Expert Review of Neurotherapeutics - July 10, 2023 Category: Neurology Authors: Shuai Sun Zhifang Li Qinghui Xiao Senwei Tan Bo Hu Huijuan Jin Source Type: research

Psychological stress is associated with arterial inflammation in people living with treated HIV infection
In conclusion, psychological stress was associated with systemic and carotid arterial inflammation in this group of PLWH with treated infection. These data provide preliminary evidence for a link between psychological stress, inflammation, and atherosclerosis as potential drivers of excess cerebrovascular risk among PLWH.PMID:37369339 | DOI:10.1016/j.bbi.2023.06.019
Source: Brain, Behavior, and Immunity - June 27, 2023 Category: Neurology Authors: Felicia C Chow Nidhi S Mundada Shady Abohashem Renaud La Joie Leonardo Iaccarino Victor M Arechiga Shreya Swaminathan Gil D Rabinovici Elissa S Epel Ahmed Tawakol Priscilla Y Hsue Source Type: research

Application of vagus nerve stimulation on the rehabilitation of upper limb dysfunction after stroke: a systematic review and meta-analysis
ConclusionVNS is an effective and safe treatment for upper extremity motor dysfunction after a stroke. For the functional restoration of the upper extremities, noninvasive integrated therapy and lower-frequency VNS may be more effective. In the future, further high-quality studies with larger study populations, more comprehensive indicators, and thorough data are required to advance the clinical application of VNS.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier: CRD42023399820.
Source: Frontiers in Neurology - June 21, 2023 Category: Neurology Source Type: research

Predictive model, miRNA-TF network, related subgroup identification and drug prediction of ischemic stroke complicated with mental disorders based on genes related to gut microbiome
ConclusionThrough comprehensive analysis, a diagnostic prediction model with good effect was obtained. Both the training group (AUC 0.82, CI 0.93–0.71) and the verification group (AUC 0.81, CI 0.90–0.72) had a good phenotype in the qRT-PCR test. And in verification group 2 we validated between the two groups with and without carotid-related ischemic cerebrovascular events (AUC 0.87, CI 1–0.64). MiRNA (hsa-mir-129-2-3p, has-mir-335-5p, and has-mir-16-5p) and TFs (CREB1, FOXL1), which may be related to IS, were obtained.
Source: Frontiers in Neurology - May 26, 2023 Category: Neurology Source Type: research

Effects of low-frequency rTMS combined with antidepressants on depression in patients with post-stroke depression: a systematic review and meta-analysis
ConclusionThe results of this meta-analysis evidenced the efficacy and safety of low-rTMS combined with antidepressants in the treatment of depression in PSD patients. The combined therapy could reduce The depression state and the levels of IL-6 and TNF-α, and enhance the cognitive function of patients. In addition, low-rTMS had fewer adverse effects, proving safety. However, there are shortcomings, such as a lack of long-term follow-up, different intervention sites of low-rTMS, and different intervention frequencies (0.5 or 1 Hz). Thus, in the future, RCTs with a larger sample size and longer-term observation are require...
Source: Frontiers in Neurology - May 19, 2023 Category: Neurology Source Type: research

Association between hysterectomy status and stroke risk and cause-specific and all-cause mortality: evidence from the 2005 –2018 National Health and Nutrition Examination Survey
ConclusionOur study found a significant association between hysterectomy and stroke, even after adjusting for other factors that could impact risk, such as the American Heart Association (AHA)'s Life's Simple 7 cardiovascular health score and variables of age, ethnicity, marital status, income, education, and depression severity.
Source: Frontiers in Neurology - May 18, 2023 Category: Neurology Source Type: research

Associations of lesion location, structural disconnection, and functional diaschisis with depressive symptoms post stroke
DiscussionBased on our results, and other recent lesion studies, we see growing evidence for a prominent role of right frontostriatal brain circuits in PSDS.
Source: Frontiers in Neurology - May 17, 2023 Category: Neurology Source Type: research

Lasting impairments following transient ischemic attack and minor stroke: a systematic review protocol
IntroductionThe focus on medical management and secondary prevention following Transient Ischemic Attack (TIA) and minor stroke is well-established. Evidence is emerging that people with TIA and minor stroke can experience lasting impairments as fatigue, depression, anxiety, cognitive impairment, and communication difficulties. These impairments are often underrecognized and inconsistently treated. Research in this area is developing rapidly and an updated systematic review is required to evaluate new evidence as it emerges. This living systematic review aims to describe the prevalence of lasting impairments and how they a...
Source: Frontiers in Neurology - May 12, 2023 Category: Neurology Source Type: research

The Future of Ischemic Stroke Diagnosis and a Review of Underrecognized Ischemic Stroke Etiologies
AbstractAccurate ischemic stroke etiologic determination and diagnosis form the foundation of excellent cerebrovascular care as from it stems initiation of the appropriate secondary prevention strategy as well as appropriate patient education regarding specific risk factors for that subtype. Recurrent stroke rates are highest among those patients who receive an incorrect initial stroke diagnosis. Patient distrust and patient reported depression are also higher. The cause of the ischemic stroke also informs predicted patient outcomes and the anticipated recovery trajectory. Finally, determining the accurate cause of the isc...
Source: Neurotherapeutics - May 8, 2023 Category: Neurology Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20