• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Hypothyroidism as a Predictor of Surgical Outcomes in the Elderly
Conclusions It is recommended to post-pone elective surgery in elderly patients with hypothyroidism until an euthyroid state is achieved. If patients need urgent or emergent surgery, it is recommended to proceed with surgery only if they have mild or moderate hypothyroidism. Replacement therapy should be started preoperatively and there should be growing attention to the possible occurrence of minor post-operative complications in hypothyroid patients. As suggested by the American Thyroid Association (ATA), the treatment in elderly patients should be initiated at low doses with slow titration based on serum TSH evaluation...
Source: Frontiers in Endocrinology - April 23, 2019 Category: Endocrinology Source Type: research

Neuromuscular blocking effects of vecuronium in dogs with autosomal-recessive centronuclear myopathy.
CONCLUSIONS AND CLINICAL RELEVANCE For the study dogs, neither potency nor duration of vecuronium-induced neuromuscular blockade was altered by CNM. Vecuronium can be used to induce neuromuscular blockade in dogs with autosomal-recessive CNM. PMID: 25815571 [PubMed - in process]
Source: American Journal of Veterinary Research - April 1, 2015 Category: Veterinary Research Authors: Martin-Flores M, Paré MD, Tomak EA, Corn ML, Campoy L Tags: Am J Vet Res Source Type: research

Mitochondria DNA Depletion Syndrome in a Infant with Multiple Congenital Malformations, Severe Myopathy, and Prolonged Postoperative Paralysis
We describe a newborn with multiple congenital malformations including a right aberrant subclavian artery and a trachea-oesophageal fistula in whom mitochondrial depletion syndrome was unmasked by perioperative muscle relaxation. After vecuronium infusion, the infant developed an irreversible postoperative paralysis, leading to death 32 days after surgery. The present case highlights (a) the clinical heterogeneity of mitochondrial depletion syndrome; (b) the importance of rigorous antemortem and postmortem investigations when the cause of a severe myopathy is uncertain; (c) the possible coexistence of mitochondrial depleti...
Source: Journal of Child Neurology - March 23, 2015 Category: Neurology Authors: Thomas, M., Salpietro, V., Canham, N., Ruggieri, M., Phadke, R., Kinali, M. Tags: Brief Communication Source Type: research