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Atrial fibrillation for internists: current practice.
Abstract Atrial fibrillation (AF) has become a global epidemic and puts affected patients at high risk of adverse events. In this review we summarise the current evidence on risk factors and complications of AF, describe current treatment strategies, and outline new fields of research. Current evidence shows that hypertension and obesity are the two most important modifiable risk factors for the development of AF. Patients with AF face an increased stroke risk. Oral anticoagulation reduces this risk substantially. Mainly for reasons of safety and ease of use, non-vitamin K antagonist oral anticoagulants are prefer...
Source: Swiss Medical Weekly - March 8, 2020 Category: General Medicine Authors: Meyre P, Conen D, Osswald S, Kühne M, Meyer-Zürn C Tags: Swiss Med Wkly Source Type: research

Rate or Rhythm Control of Atrial Fibrillation - Pearls for the Internist.
Abstract Atrial fibrillation is an epidemic in Asia that is increasingly prevalent. Apart from stroke risk stratification and management of anticoagulation, physicians managing this group of patients also need to determine an optimal strategy in terms of rate or rhythm control. With new techniques of catheter ablation to maintain patients in sinus rhythm, patients with atrial fibrillation now have more options for treatment, on top of pharmacological methods. This paper aims to review the current evidence for rate and rhythm control in both general patients and subgroups of interest commonly encountered in clinica...
Source: Annals of the Academy of Medicine, Singapore - November 1, 2017 Category: General Medicine Authors: Huang W, Keng FY, Ching CK Tags: Ann Acad Med Singapore Source Type: research

The Limited Public Health Impact of ‘Lifestyle’ Change
Two main factors are responsible for premature disease and mortality. One is smoking, often referred to as a “lifestyle choice,” but better described as a “habit.” The other is poor nutrition resulting largely from the sugar, alcohol, salt, and saturated fat content (SASS components) of ready-to-consume food and drink, much of which is manufactured on an industrial scale. Collectively, these dietar y components are the main drivers of the global epidemic of stroke, heart attack, obesity, and type 2 diabetes.
Source: The American Journal of Medicine - July 14, 2016 Category: Journals (General) Authors: Nicholas J. Wald Tags: Editorial Source Type: research

The limited public health impact of “lifestyle” change
Two main factors are responsible for premature disease and mortality. One is smoking, often referred to as a “lifestyle choice”, but better described as a “habit”. The other is poor nutrition resulting largely from the sugar, alcohol, salt, and saturated fat content (SASS components) of ready to consume food and drink, much of which is manufactured on an industrial scale. Collectively these dietary components are the main drivers of the global epidemic of stroke, heart attack, obesity, and type 2 diabetes.
Source: The American Journal of Medicine - July 14, 2016 Category: Journals (General) Authors: Nicholas J. Wald Tags: Editorial Source Type: research

Progress Against Heart Deaths Starting to Wane, Report Warns
WEDNESDAY, June 29, 2016 -- America's war on heart disease and stroke may have suffered a setback. A new study warns that the rate of decline in deaths from heart disease and stroke has stalled. "It is likely that the dual epidemics of obesity and...
Source: Drugs.com - Daily MedNews - June 29, 2016 Category: Journals (General) Source Type: news

Pharmacotherapy of obesity: clinical treatments and considerations.
Abstract Obesity is a world-wide epidemic associated with significant morbidity and mortality which costs billions of dollars per year. The associated related conditions are many and include heart disease, stroke, type II diabetes mellitus, sleep apnea and certain types of cancer. Given that it is a multifactorial problem, the treatments must also address the numerous causes associated with the development of obesity. The neurohormonal regulation of feeding and energy is a complex system often necessitating modification through more than 1 pathway to achieve weight loss. Therefore, in addition to lifestyle changes...
Source: The American Journal of the Medical Sciences - April 1, 2013 Category: Journals (General) Authors: Holes-Lewis KA, Malcolm R, O'Neil PM Tags: Am J Med Sci Source Type: research