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Condition: Cholesterol
Procedure: Coronary Angioplasty
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Total 265 results found since Jan 2013.
Antibody-mediated PCSK9 neutralization worsens outcome after bare-metal stent implantation in mice
CONCLUSION: Antibody-based PCSK9 inhibition promotes in-stent intimal hyperplasia and blunts vascular healing by increasing VSMC migration, while reducing that of EC. This effect is likely mediated, at least in part, by a differential effect on VSMC and EC senescence. The herein-reported data warrant additional investigations concerning the use of PCSK9 inhibitors in patients undergoing PCI with stent implantation.PMID:37659608 | DOI:10.1016/j.vph.2023.107170
Source: Atherosclerosis - September 2, 2023 Category: Cardiology Authors: Yustina M Puspitasari Stefano Ministrini Luca Liberale Ana Vukolic Philine Baumann-Zumstein Erik W Holy Fabrizio Montecucco Thomas F L üscher Giovanni G Camici Source Type: research
Acute Myocardial Infarction and Risk of Cognitive Impairment and Dementia: A Review
Biology (Basel). 2023 Aug 21;12(8):1154. doi: 10.3390/biology12081154.ABSTRACTCognitive impairment (CI) shares common cardiovascular risk factors with acute myocardial infarction (AMI), and is increasingly prevalent in our ageing population. Whilst AMI is associated with increased rates of CI, CI remains underreported and infrequently identified in patients with AMI. In this review, we discuss the evidence surrounding AMI and its links to dementia and CI, including pathophysiology, risk factors, management and interventions. Vascular dysregulation plays a major role in CI, with atherosclerosis, platelet activation, microin...
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: Elizabeth Hui En Thong Ethan J W Quek Jing Hong Loo Choi-Ying Yun Yao Neng Teo Yao Hao Teo Aloysius S T Leow Tony Y W Li Vijay K Sharma Benjamin Y Q Tan Leonard L L Yeo Yao Feng Chong Mark Y Chan Ching-Hui Sia Source Type: research
Impact of age on pre-procedural TIMI flow in STEMI patients undergoing primary percutaneous coronary intervention
CONCLUSION: The present study shows that among STEMI patients undergoing primary PCI, more advanced age represents an independent predictor of preprocedural IRA patency. Future studies will define the implications on procedural results and long-term prognosis.PMID:37605955 | DOI:10.2459/JCM.0000000000001482
Source: Atherosclerosis - August 22, 2023 Category: Cardiology Authors: Monica Verdoia Rocco Gioscia Orazio Viola Marta Francesca Brancati Pier Luigi Sold à Andrea Rognoni Giuseppe De Luca Novara Atherosclerosis Study Group (NAS) Source Type: research
Effect of Alirocumab Added to High-Intensity Statin on Platelet Reactivity and Non-coding RNAs in AMI Patients: A Substudy of the PACMAN-AMI Trial
CONCLUSIONS: Among AMI patients receiving DAPT with a potent P2Y12 inhibitor, alirocumab had no significant effect on platelet reactivity as assessed by PRU and platelet-derived non-coding RNAs.PMID:37595625 | DOI:10.1055/a-2156-7872
Source: Thrombosis and Haemostasis - August 18, 2023 Category: Hematology Authors: Yasushi Ueki Jonas H äner Sylvain Losdat Giuseppe Gargiulo Hiroki Shibutani Sarah B är Tatsuhiko Otsuka Raminta Kavaliauskaite Vera Mitter Fabrice Temperli David Spirk Stefan Stortecky George Siontis Marco Valgimigli Stephan Windecker Clemens Gutmann Ko Source Type: research
Impact of Atherothrombotic risk stratification in patients with heavily calcified lesions following rotational Atherectomy
CONCLUSIONS: Atherothrombotic risk stratification using TRS 2°P was useful in identifying high-risk patients with heavily calcified lesions following RA.PMID:37524300 | DOI:10.1016/j.jjcc.2023.07.013
Source: Journal of Cardiology - July 31, 2023 Category: Cardiology Authors: Toru Yoshizaki Takamitsu Nakamura Takeo Horikoshi Yosuke Watanabe Tsuyoshi Kobayashi Yukio Saito Jun-Ei Obata Takao Sawanobori Hajime Takano Ken Umetani Tetsuya Asakawa Akira Sato Source Type: research
