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Nationwide Experience of Cardio- and Cerebrovascular Complications During Infrainguinal Endovascular Intervention for Peripheral Arterial Disease and Acute Limb Ischaemia
Conclusions: In this population-based study we found a low risk of cardiac complications, but catheter-administered thrombolytic therapy entailed a non-negligible risk of major stroke.
Source: European Journal of Vascular and Endovascular Surgery - January 21, 2013 Category: Surgery Authors: J. Nordanstig, K. Smidfelt, M. Langenskiöld, B. Kragsterman Tags: Peripheral Arterial Disease Source Type: research

Nationwide Experience of Cardio- and Cerebrovascular Complications During Infrainguinal Endovascular Intervention for Peripheral Arterial Disease and Acute Limb Ischaemia.
CONCLUSIONS: In this population-based study we found a low risk of cardiac complications, but catheter-administered thrombolytic therapy entailed a non-negligible risk of major stroke. PMID: 23333098 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - January 17, 2013 Category: Surgery Authors: Nordanstig J, Smidfelt K, Langenskiöld M, Kragsterman B Tags: Eur J Vasc Endovasc Surg Source Type: research

Effects of successful percutaneous lower extremity revascularization on cardiovascular outcome in patients with peripheral arterial disease
Conclusions: This study shows that successful revascularization of LE-PAD patients affected by intermittent claudication, in addition to improving functional status, reduces the occurrence of future major cardiovascular events.
Source: International Journal of Cardiology - July 12, 2012 Category: Cardiology Authors: Giuseppe Giugliano, Luigi Di Serafino, Cinzia Perrino, Vittorio Schiano, Eugenio Laurenzano, Salvatore Cassese, Mario De Laurentis, Gabriele Giacomo Schiattarella, Linda Brevetti, Anna Sannino, Giuseppe Gargiulo, Anna Franzone, Ciro Indolfi, Federico Pisc Tags: Original Articles Source Type: research

ApoA-1 Mimetic Peptides Promoting Lipid Efflux from Cells for Treatment of Vascular Disorders
This invention involves ApoA-1 mimetic peptides with multiple amphipathic alpha-helical domains that promote lipid efflux from cells and are useful in the treatment and prevention of dyslipidemic, inflammatory and vascular disorders. IND-enabling studies for one of the peptides, named Fx-5A, are completed in preparation for an IND filing at the FDA, to be followed by a Phase I clinical trial planned for 2017. Disorders amenable to treatment with the peptides include hyperlipidemia, hyperlipoproteinemia, hypercholesterolemia, HDL deficiency, hypertriglyceridemia, apoA-I deficiency, acute coronary syndrome, angina pectoris, ...
Source: NIH OTT Licensing Opportunities - February 1, 2008 Category: Research Authors: ajoyprabhu3 Source Type: research

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