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Central Nervous System involvement in tuberculosis: an MRI study considering differences between patients with and without Human Immunodeficiency Virus 1 infection
Conclusions Stroke involving the basal ganglia best differentiates CNSTB patients who are HIV+ from those HIV-. This finding was not correlated with meningeal enhancement suggesting that small arteries involvement might precede it. Therefore, we think that HIV+ patients with a new onset of stroke should be evaluated for CNSTB. Follow-up MRI should also be planned since meningeal enhancement might appear in later stages of the disease.
Source: Journal of Neuroradiology - September 18, 2019 Category: Radiology Source Type: research

Trends and Characteristics of Tuberculous Meningitis in the United States, 1993-2013 (S30.007)
Conclusions:Over the past two decades, the incidence and mortality of TBM in the US have steadily declined, but neurological complications are increasing.Study Supported by:This work was supported by the National Institute of Neurological Disorders [grant numbers K23NS082367, R01NS097443-01 to H.K.] and the Michael Goldberg Stroke Research Fund to [H.K.].Disclosure: Dr. Merkler has nothing to disclose. Dr. Chatterjee has nothing to disclose. Dr. Gialdini has nothing to disclose. Dr. Reynolds has nothing to disclose. Dr. Morris has nothing to disclose. Dr. Murthy has nothing to disclose. Dr. Thakur has received personal com...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Merkler, A., Chatterjee, A., Gialdini, G., Reynolds, A., Morris, N., Murthy, S., Thakur, K., Kamel, H. Tags: Infectious Disease: HIV, Syphilis, Borrelia, TB, Cysticercosis, and Other Infections Source Type: research

Cerebral infarction and tuberculoma in central nervous system tuberculosis: frequency and prognostic implications
Conclusions Tuberculomas were present in 50% of patients, while infarcts were present in 25%. Old age, TBM grading, presence of infarction and hydrocephalus were all predictors of poor outcome.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 17, 2014 Category: Neurosurgery Authors: Wasay, M., Farooq, S., Khowaja, Z. A., Bawa, Z. A., Ali, S. M., Awan, S., Beg, M. A., Mehndiratta, M. M. Tags: Meningitis, Hydrocephalus, Infection (neurology), Stroke Neuroinfection Source Type: research

Cerebral venous thrombosis during tuberculous meningoencephalitis.
Abstract Cerebral venous thrombosis is a rare disease characterized by its clinical polymorphism and multiplicity of risk factors. Infections represent less than 10% of etiologies. Tuberculosis is not a common etiology, only a few observations are published in the literature. Between January 2005 and March 2015, 61 patients were hospitalized for neuro-meningeal tuberculosis. Among them, three young women had presented one or more cerebral venous sinus thromboses. No clinical feature was observed in these patients; vascular localizations were varied: sagittal sinus (2 cases), lateral sinus (2 cases) and transver...
Source: Journal des Maladies Vasculaires - April 14, 2016 Category: Cardiology Authors: Guenifi W, Boukhrissa H, Gasmi A, Rais M, Ouyahia A, Hachani A, Diab N, Mechakra S, Lacheheb A Tags: J Mal Vasc Source Type: research

A Rare Case of Central Nervous System Tuberculosis Presenting as Transient Splenial Lesion: Case Report and Literature Review (P1.320)
Conclusions:Based on literature review, the transient splenial lesion of corpus callosum has never been reported in patients with CNS tuberculosis. The mechanisms underlying transient splenial lesions may due to intramyelinic edema and inflammatory cell infiltration. This hypothesis supported by the MR spectroscopy findings in our patient. Since early diagnosis and treatment can reduce mortality and morbidity, patients with isolated splenial lesion warrant diagnostic tests for CNS tuberculosis.Study Supported by:The authors report no disclosures relevant to the manuscript.Disclosure: Dr. Wu has nothing to disclose. Dr. Che...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Wu, J.-W., Chen, S. Tags: Autoimmunity with Infection, Syphilis, Lyme, Tuberculosis, and other Bacteria Source Type: research

Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report
We describe a case of an Italian child. Diagnoses: we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and paradoxical reaction with brain pseudo-abscesses. Interventions: The child started readily a specific therapy associated with steroids and thalidomide was introduced few month later. Outcomes: the patient had a favorable outcome without neurologic sequelae. Lessons: Despite the prompt specific anti-tubercular and adjuvant corticosteroid therapies, only the addition of thalidomide to the treatment allow to a favorable clinical outcome.
Source: Medicine - July 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Clinical Significance of Delirium With Catatonic Signs in Patients With Neurological Disorders
CONCLUSIONS: Delirium is a common complication of neurological diseases, and it can coexist with catatonia. The recognition of catatonic delirium has clinical significance in terms of etiology, as it was significantly associated with viral and anti-NMDAR encephalitis.PMID:35040665 | DOI:10.1176/appi.neuropsych.18120364
Source: Journal of Neuropsychiatry and Clinical Neurosciences - January 18, 2022 Category: Psychiatry Authors: Jesus Ramirez-Bermudez Angela Medina-Gutierrez Heraclides Gomez-Cianca Patricia Arias Andres P érez-Gonzalez Paulina Ang élica Lebrija-Reyes Mariana Espinola-Nadurille Luis Carlos Aguilar-Venegas Carmen Ojeda-L ópez Miguel Restrepo-Mart ínez Leo Bayli Source Type: research