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YiQiFuMai Powder Injection Attenuates Coronary Artery Ligation-Induced Heart Failure Through Improving Mitochondrial Function via Regulating ROS Generation and CaMKII Signaling Pathways
This study was carried out in accordance with the recommendations of “Guide for the Care and Use of Laboratory Animals, National Institutes of Health.” The protocol was approved by the “China Pharmaceutical University.” Surgical Preparation The mice were anesthetized with chloral hydrate (4% chloral hydrate, ip). The HF model was induced by CAL as previously reported (Gao et al., 2010). Successful ligation of the coronary artery was confirmed by the occurrence of ST-segment elevation in electrocardiogram. Sham operated mice were performed the same process except left CAL. After ligation, the h...
Source: Frontiers in Pharmacology - April 9, 2019 Category: Drugs & Pharmacology Source Type: research

Association between Exposure to p,p ′-DDT and Its Metabolite p,p′-DDE with Obesity: Integrated Systematic Review and Meta-Analysis
Conclusions: We classified p,p′-DDT and p,p′-DDE as “presumed” to be obesogenic for humans, based on a moderate level of primary human evidence, a moderate level of primary in vivo evidence, and a moderate level of supporting evidence from in vivo and in vitro studies. https://doi.org/10.1289/EHP527 Received: 17 May 2016 Revised: 04 May 2017 Accepted: 09 May 2017 Published: 18 September 2017 Please address correspondence to M.A. La Merrill, Dept. of Environmental Toxicology, University of California, Davis, 1 Shields Ave., 4245 Meyer Hall, Davis, CA 95616-5270 USA. Telephone: (530) 754-7254. Email: mlamerrill...
Source: EHP Research - September 18, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research

Science Scandal Triggers Suicide, Soul-Searching in Japan
It was a success story that Japan sorely needed: a young, talented and beautiful researcher developed a cheap and simple way to grow versatile stem cells. MoreTokyo: What to See and What to SkipThis Is How TIME Explained the Atomic Bomb in 1945Iselle Weakens to Tropical Storm as Julio Barrels On NBC NewsIsrael Vows to 'Forcefully React' as Cease-Fire Ends NBC NewsCops Tampered With Pistorius Evidence, Lawyer Alleges NBC NewsThe discovery promised to usher in a new age of regenerative medicine, validated Japan as a leader in scientific research and demonstrated that even in a male-dominated society, women could excel when g...
Source: TIME.com: Top Science and Health Stories - August 8, 2014 Category: Consumer Health News Authors: Charlie Campbell Tags: Uncategorized haruko obokata Japan Research Science Stem Cells Suicide Yoshiki Sasai Source Type: news