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Specialty: Primary Care
Condition: Heart Failure

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Total 75 results found since Jan 2013.

Association between serum uric acid levels and cardiovascular events in hospitalized patients with type 2 diabetes
CONCLUSIONS: In hospitalized patients with T2DM, baseline serum UA levels were positively associated with cardiovascular events in women, but not in men. Serum UA levels may be a significant independent risk factor for cardiovascular events in women with T2DM.PMID:33849815 | DOI:10.1016/j.pcd.2021.03.003
Source: Primary Care - April 14, 2021 Category: Primary Care Authors: Zhan Chang Xiang-Hai Zhou Xin Wen Source Type: research

Novel Targets for Hypertension Drug Discovery
AbstractPurpose of ReviewDespite the availability of various medications and prescribing combination therapies, uncontrolled blood pressure and resistance are observed in more than 40% of patients. The purpose of this review is to discuss emerging novel approaches for the treatment of hypertension and propose future research and clinical directions.Recent FindingsHypertension is a common disease of the cardiovascular system which may arise solely or as a comorbidity of other disorders. It is a crucial risk factor for cardiovascular diseases such as coronary artery disease, myocardial infarction, congestive heart failure, r...
Source: Current Hypertension Reports - March 30, 2021 Category: Primary Care Source Type: research

Guidelines for screening and managing hypertension in children
This article reviews the definition of pediatric hypertension, describes why the guidelines were updated, and defines treatment protocol. By familiarizing themselves with and applying these guidelines, clinicians will be able to appropriately screen and manage hypertension in children to prevent morbidity into adulthood.
Source: Journal of the American Academy of Physician Assistants - December 24, 2020 Category: Primary Care Tags: CME: Pediatrics Source Type: research

Heart Disease in Adults With Down Syndrome Between 1996 and 2016
Conclusion: Adults with DS generally experience less heart disease and associated risk conditions commonly seen in the general population. Prevention and treatment guidelines for heart disease for the DS population should be adjusted after more research is conducted.
Source: Journal of the American Board of Family Medicine - November 20, 2020 Category: Primary Care Authors: Fitzpatrick, V., Rivelli, A., Bria, K., Chicoine, B. Tags: Original Research Source Type: research

The epidemiology of atrial fibrillation in Chinese postmenopausal women and its association with age of menopause
As the most common arrhythmia, atrial fibrillation (AF) remains one of the major disease leading to stroke, heart failure and mortality in the world. [1] Although the prevalence of AF is lower in female than male [2], female with AF are more likely to develop stroke and death than male [3,4]. The risk of cardiovascular disease (CVD) in postmenopausal women increases markedly, especially after the cessation of ovarian function [5]. Therefore, it is imperative to better understand the prevalence trends and management status of AF in postmenopausal women and develop effective prevention strategies to improve the prognosis of ...
Source: Maturitas - October 23, 2020 Category: Primary Care Authors: Zhi Du, Boqiang Zhang, Min Lin, Yuanmeng Tian, Li Jing, Shuang Liu, Yanhong Cheng, Lei Shi, Yingxian Sun, Liying Xing Source Type: research

A Contemporary Approach to Hypertensive Cardiomyopathy: Reversing Left Ventricular Hypertrophy
AbstractPurpose of ReviewTo highlight pharmacological and non-pharmacological approaches to reversing hypertensive left ventricular hypertrophy (LVH). We identify high-risk phenotypes that may benefit from aggressive blood pressure (BP) management to prevent incident outcomes such as the development of atherosclerotic cardiovascular disease, stroke, and heart failure.Recent FindingsLVH is a modifiable risk factor. Intensive BP lowering (systolic BP<  120 mmHg) induces greater regression of electrocardiographic LVH than standard BP targets. The optimal agents for inducing LVH regression include renin–angiotensinogen...
Source: Current Hypertension Reports - September 4, 2020 Category: Primary Care Source Type: research

Do patients or their physicians more accurately assess long-term risk associated with hypertension? A population-based study.
Conclusions: Patients were better than their physicians in estimating the average probability of morbidity due to hypertension. Both the patients and their attending physicians had difficulty in estimating the individual patient's risk of complications. The results support the use of evidence-based tools in consultations for assessing the risk of cardiovascular complications associated with hypertension.KeywordsHypertension; cardiovascular diseases/prevention & control; risk assessment, algorithms; decision making; prospective studiesKey points • Shared decision making relies on a common understanding of risks an...
Source: Primary Care - May 1, 2020 Category: Primary Care Authors: Hoffmann M, Nilsson PM, Ahlner J, Dahllöf B, Fredrikson M, Säljö R, Kjellgren KI Tags: Scand J Prim Health Care Source Type: research

Anticipating the management of Streptococcus agalactiae infective endocarditis
A patient who presented after falling out of bed had signs of right-sided stroke, which, after imaging, was suspicious for embolism with cardiac origin. Further investigation revealed a large aortic valve vegetation with mild aortic insufficiency, and the patient eventually developed heart failure requiring surgical intervention. Infective endocarditis is slowly becoming more prevalent, and clinicians should have a high index of suspicion when patients present with common complications of this disease, such as valvular dysfunction, heart failure, or stroke. Early diagnosis has been shown to reduce time to appropriate antib...
Source: Journal of the American Academy of Physician Assistants - April 28, 2020 Category: Primary Care Tags: Case Report Source Type: research

Opportunistic screening versus usual care for diagnosing atrial fibrillation in general practice: a cluster randomised controlled trial.
CONCLUSION: Opportunistic screening with a single-lead ECG at the discretion of the GP did not result in a higher yield of newly detected cases of AF in patients aged ≥65 years in the community than usual care. For higher participation rates in future studies, more rigorous screening methods are needed. PMID: 31988084 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - January 26, 2020 Category: Primary Care Authors: Kaasenbrood F, Hollander M, de Bruijn SH, Dolmans CP, Tieleman RG, Hoes AW, Rutten FH Tags: Br J Gen Pract Source Type: research

Legacy Effect in the Treatment of Hypertension: Persistent Cardiovascular Protection after Conclusion of Randomized Clinical Trials in Hypertension
AbstractRecent FindingsEssential hypertension is the main determinant of cardiovascular morbidity and mortality worldwide. During the last decades, several antihypertensive drug therapies have been introduced and tested in clinical trials, both as monotherapies and combination therapies. The current recommended therapeutic approaches effectively reduce the lifetime risk of experiencing major cardiovascular outcomes and disabling comorbidities, such as myocardial infarction, stroke, and congestive heart failure. On the basis of multiple proofs, antihypertensive therapy is currently recommended for improving event-free survi...
Source: Current Hypertension Reports - October 9, 2019 Category: Primary Care Source Type: research

Dapagliflozin in High-Risk Type 2 Diabetes Reduces Hospitalization for Heart Failure But Does Not Reduce Death, Myocardial Infarction, or Stroke.
PMID: 31361104 [PubMed - in process]
Source: American Family Physician - July 31, 2019 Category: Primary Care Authors: Ebell MH Tags: Am Fam Physician Source Type: research

Pharmacologic and Nonpharmacologic Management of Atrial Fibrillation
Atrial fibrillation (AF) is the most common arrhythmia and its management may be organized into risk stratification and/or treatment of heart failure, stroke prevention, and symptom control. At the core of symptom control, treatment is tailored to either allow AF continue with controlled heart rates, so-called rate control, versus restoring and maintaining sinus rhythm or rhythm control. Rate control strategies mainly use rate-modulating medications, whereas rhythm control treatment includes therapy aimed at restoring sinus rhythm, including pharmacologic and direct current cardioversion, as well as maintenance of sinus rh...
Source: Medical Clinics of North America - June 30, 2019 Category: Primary Care Authors: Vishal Dahya, Tyler L. Taigen Source Type: research

Comorbidity in patients with cardiovascular disease in primary care: a cohort study with routine healthcare data.
CONCLUSION: Comorbid conditions are very common in patients with CVD, even in younger age groups. To ensure efficient and effective treatment, organisational adaptations may be required in the healthcare system to accommodate comorbid conditions in patients with CVD. PMID: 31064742 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - May 6, 2019 Category: Primary Care Authors: Buddeke J, Bots ML, van Dis I, Visseren FL, Hollander M, Schellevis FG, Vaartjes I Tags: Br J Gen Pract Source Type: research

The new GP contract: transforming primary care, transforming CVD prevention
NHS England ’s National Clinical Director for Cardiovascular Disease Prevention and the Chief Executive of the British Heart Foundation share their thoughts on the new GP contract and the positive impact that the changes could have on the outcomes and quality of life for people across the country Related items fromOnMedica Invest in GP services to improve heart failure survival Statins cut risk of strokes/heart attacks irrespective of patient ’s age Ending the postcode lottery of stroke care Hypertension: what ’s new and how might this impact practice? Know your heart health risk stats as well as your PIN number, public urged
Source: OnMedica Views - February 25, 2019 Category: Primary Care Source Type: news

Real-world retrospective cohort study ARCTIC shows burden of comorbidities in Swedish COPD versus non-COPD patients.
This study aimed to generate real-world evidence to assess the burden of comorbidities in COPD patients, to effectively manage these patients and optimize the associated healthcare resource allocation. ARCTIC is a large, real-world, retrospective cohort study conducted in Swedish COPD patients using electronic medical record data collected between 2000 and 2014. These patients were studied for prevalence of various comorbidities and for association of these comorbidities with exacerbations, mortality, and healthcare costs compared with an age-, sex-, and comorbidities-matched non-COPD reference population. A total of 17,47...
Source: Primary Care - September 10, 2018 Category: Primary Care Authors: Ställberg B, Janson C, Larsson K, Johansson G, Kostikas K, Gruenberger JB, Gutzwiller FS, Jorgensen L, Uhde M, Lisspers K Tags: NPJ Prim Care Respir Med Source Type: research