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Design of the Swiss Atrial Fibrillation Cohort Study (Swiss-AF): structural brain damage and cognitive decline among patients with atrial fibrillation.
CONCLUSION: Swiss-AF is a large national prospective cohort of patients with AF in Switzerland. This study will provide important new information on structural and functional brain damage in patients with AF and on other AF related complications, using a large variety of genetic, phenotypic and health economic parameters. PMID: 28695548 [PubMed - in process]
Source: Swiss Medical Weekly - July 11, 2017 Category: General Medicine Authors: Conen D, Rodondi N, Mueller A, Beer J, Auricchio A, Ammann P, Hayoz D, Kobza R, Moschovitis G, Shah D, Schlaepfer J, Novak J, di Valentino M, Erne P, Sticherling C, Bonati L, Ehret G, Roten L, Fischer U, Monsch A, Stippich C, Wuerfel J, Schwenkglenks M, K Tags: Swiss Med Wkly Source Type: research

Cardiovascular disease after childhood acute lymphoblastic leukaemia: a cohort study.
CONCLUSIONS: Despite attempts to reduce cardiotoxicity in childhood cancer treatment, CVD risks in ALL survivors treated more recently do not seem to have declined. PMID: 30852834 [PubMed - in process]
Source: Swiss Medical Weekly - February 24, 2019 Category: General Medicine Authors: Hau EM, Caccia JN, Kasteler R, Spycher B, Suter T, Ammann RA, von der Weid NX, Kuehni CE Tags: Swiss Med Wkly Source Type: research

Association of Acute Kidney Injury with Cardiovascular Events and Death in Systolic Blood Pressure Intervention Trial.
CONCLUSIONS: Among older adults with hypertension at high cardiovascular risk, intensive treatment of blood pressure independently increased risk of AKI, which substantially raised risks of major cardiovascular events and death. PMID: 30939480 [PubMed - as supplied by publisher]
Source: American Journal of Nephrology - April 1, 2019 Category: Urology & Nephrology Authors: Dieter BP, Daratha KB, McPherson SM, Short R, Alicic RZ, Tuttle KR Tags: Am J Nephrol Source Type: research

Design and Baseline Characteristics of the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease Trial.
CONCLUSIONS: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. TRIAL REGISTRATION: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049. PMID: 31665733 [PubMed - as supplied by publisher]
Source: American Journal of Nephrology - October 29, 2019 Category: Urology & Nephrology Authors: Ruilope LM, Agarwal R, Anker SD, Bakris GL, Filippatos G, Nowack C, Kolkhof P, Joseph A, Mentenich N, Pitt B, FIGARO-DKD study investigators Tags: Am J Nephrol Source Type: research

Impact of Cardio-Renal-Metabolic Comorbidities on Cardiovascular Outcomes and Mortality in Type 2 Diabetes Mellitus.
CONCLUSION: In T2DM patients, CKD presence was associated with higher risk of modified MACE, HF, and ACM. This may have risk-stratification implications for T2DM patients based on background CKD and highlights the potential importance of novel renoprotective strategies. PMID: 31812955 [PubMed - as supplied by publisher]
Source: American Journal of Nephrology - December 5, 2019 Category: Urology & Nephrology Authors: Cherney DZI, Repetto E, Wheeler DC, Arnold SV, MacLachlan S, Hunt PR, Chen H, Vora J, Kosiborod M Tags: Am J Nephrol Source Type: research

Subclinical Thyroid Function and Cardiovascular Events in patients with Atrial Fibrillation
CONCLUSIONS: Subclinical hypothyroidism was not associated with increased CV risk in AF patients. Higher levels of fT4 with normal TSH were associated with higher risk for HF.PMID:34228632 | DOI:10.1530/EJE-20-1442
Source: European Journal of Endocrinology - July 6, 2021 Category: Endocrinology Authors: Elisavet Moutzouri Christina Lyko Martin Feller Manuel Raphael Blum Luise Adam Steffen Blum Stefanie Aeschbacher Urs Fischer Laurent Roten Cinzia Del Giovane Christine S Meyer-Zuern Giulio Conte Leo H Bonati Giorgio Moschovitis Michael Kuehne Juerg Beer D Source Type: research

Heat-related cardiovascular morbidity and mortality in Switzerland: a clinical perspective
CONCLUSIONS: Volume depletion and vasodilation from heat stress plausibly explain the risk reduction of heat-related emergency hospital admissions for hypertension and heart failure. Since primary cause of death mostly refers to the underlying chronic disease, the seemingly paradoxical heat-related mortality increase can plausibly be explained by an exacerbation of heat effects by antihypertensive and diuretic drugs. Clinical guidelines should consider recommending strict therapy monitoring of such medication during heatwaves, particularly in the elderly.PMID:34519461 | DOI:10.4414/SMW.2021.w30013
Source: Swiss Medical Weekly - September 14, 2021 Category: General Medicine Authors: Florian Schulte Martin R öösli Martina S Ragettli Source Type: research

Mutual effects of fine particulate matter, nitrogen dioxide, and fireworks on cause-specific acute cardiovascular mortality: A case-crossover study in communities affected by aircraft noise
This study confirms the association between ambient NO2, as a marker for primary emissions, and acute cardiovascular mortality in a specific setting around a major airport. Future research should clarify the role of additional air pollutants including ultra-fine particles on cardiovascular diseases to inform most efficient control measures.PMID:34536646 | DOI:10.1016/j.envpol.2021.118066
Source: Environmental Pollution - September 18, 2021 Category: Environmental Health Authors: Apolline Saucy Kees de Hoogh Danielle Vienneau Louise Tangermann Beat Sch äffer Jean-Marc Wunderli Nicole Probst-Hensch Martin R öösli Source Type: research

Heat-related cardiovascular morbidity and mortality in Switzerland: a clinical perspective
CONCLUSIONS: Volume depletion and vasodilation from heat stress plausibly explain the risk reduction of heat-related emergency hospital admissions for hypertension and heart failure. Since primary cause of death mostly refers to the underlying chronic disease, the seemingly paradoxical heat-related mortality increase can plausibly be explained by an exacerbation of heat effects by antihypertensive and diuretic drugs. Clinical guidelines should consider recommending strict therapy monitoring of such medication during heatwaves, particularly in the elderly.PMID:34519460 | DOI:10.4414/SMW.2021.w30013
Source: Swiss Medical Weekly - September 14, 2021 Category: General Medicine Authors: Florian Schulte Martin R öösli Martina S Ragettli Source Type: research

Transapical Transcatheter Mitral Valve Implantation with the Tendyne Valve: The Swiss Experience
Conclusion Transcatheter mitral valve implantation with Tendyne is feasible to treat polymorbid patients suffering from complex mitral valve disease as well as patients with previous mitral interventions. Perioperative risk was acceptable and procedural success high. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: The Thoracic and Cardiovascular Surgeon - June 16, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Nucera, Maria Miazza, Jules Praz, Fabien Kaiser, Christoph Siepe, Matthias Reineke, David Reuthebuch, Oliver Tags: Original Cardiovascular Source Type: research

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