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Specialty: Urology & Nephrology
Condition: Glomerulonephritis
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Total 3845 results found since Jan 2013.
Characteristics of Complement Protein Deposition in Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposition
CONCLUSIONS: The complement system was found to be overactivated in PGNMID, and levels of urinary complements correlated with disease severity. A higher level of urinary C4d was identified as an independent risk factor for kidney failure.PMID:37713183 | DOI:10.2215/CJN.0000000000000295
Source: Clinical Journal of the American Society of Nephrology : CJASN - September 15, 2023 Category: Urology & Nephrology Authors: Meng-Yao Liu Xiao-Juan Yu Su-Xia Wang Yuan Li Guolan Xing Ming Chen Fu-de Zhou Ming-Hui Zhao Source Type: research
Mesangial C3 Deposition, Complement-Associated Variant, and Disease Progression in IgA Nephropathy
CONCLUSIONS: We found that in Chinese patients with IgA nephropathy, variant rs6677604 was associated with mesangial C3 deposition, and mesangial C3 deposition, but not rs6677604, was associated with IgA nephropathy severity and progression.PMID:37651123 | DOI:10.2215/CJN.0000000000000290
Source: Clinical Journal of the American Society of Nephrology : CJASN - August 31, 2023 Category: Urology & Nephrology Authors: Yuqi Kang Boyang Xu Sufang Shi Xujie Zhou Pei Chen Lijun Liu Yebei Li Yueqi Leng Jicheng Lv Li Zhu Hong Zhang Source Type: research
Rare Variants in Complement Gene in C3 Glomerulopathy and Immunoglobulin-Mediated Membranoproliferative Glomerulonephritis
CONCLUSIONS: In our cohort, 17% of C3 glomerulopathy/Ig-MPGN cases were associated with rare variants in the CFH, CFI, or C3 genes. In the majority of cases, a quantitative deficiency in factor H or factor I is identified. The presence of a rare variant was associated with poor kidney survival.PMID:37615951 | DOI:10.2215/CJN.0000000000000252
Source: Clinical Journal of the American Society of Nephrology : CJASN - August 24, 2023 Category: Urology & Nephrology Authors: Marie Sophie Meuleman Paula Vieira Martins Carine El Sissy Vincent Audard V éronique Baudouin Dominique Bertrand Frank Bridoux F érielle Louillet Claire Dossier Vincent Esnault No émie Jourde-Chiche Alexandre Karras Marie-Pascale Morin Fran çois Provo Source Type: research
Renal pathology in adult and paediatric population of Japan: review of the Japan renal biopsy registry database from 2007 to 2017
CONCLUSIONS: This study describes the distribution and changes in kidney biopsy diagnoses over 10 years in Japan and paves the way for future research on kidney diseases in adults and children.PMID:37597092 | DOI:10.1007/s40620-023-01687-9
Source: Journal of Nephrology - August 19, 2023 Category: Urology & Nephrology Authors: Kazunori Goto Takahiro Imaizumi Riku Hamada Kenji Ishikura Tomoki Kosugi Ichiei Narita Hitoshi Sugiyama Akira Shimizu Hitoshi Yokoyama Hiroshi Sato Shoichi Mauryama Source Type: research
Human parietal epithelial cells (PECs) and proteinuria in lupus nephritis: a role for ClC-5, megalin, and cubilin?
CONCLUSIONS: Our results may provide further insight into the role of hypertrophic parietal epithelial cells located at the tubular pole and their possible involvement in protein endocytosis in lupus nephritis patients. These data also suggest that the presence of hypertrophic parietal epithelial cells in Bowman's capsule represents a potential resource for responding to protein overload observed in other glomerulonephritis.PMID:37594671 | DOI:10.1007/s40620-023-01725-6
Source: Journal of Nephrology - August 18, 2023 Category: Urology & Nephrology Authors: Monica Ceol Lisa Gianesello Hernan Trimarchi Alberto Migliorini Giovanna Priante Claudia M Radu Elena Naso Annalisa Angelini Lorenzo A Cal ò Franca Anglani Dorella Del Prete Source Type: research
Lower limb arterial thrombosis in an adult with membranous glomerulonephritis
Clin Nephrol. 2023 Aug 7. doi: 10.5414/CN111046. Online ahead of print.ABSTRACTMassive proteinuria and hypoalbuminemia are potential risk factors in thromboembolic complications. Venous thrombosis is a frequent complication of thromboembolism in patients with membranous glomerulonephritis, while arterial thrombosis is much less reported. A 35-year-old man presented with nephrotic syndrome and osteofascial compartment syndrome in the right lower limb due to arterial thrombosis. The biopsy findings were consistent with those of stage 2 membranous nephropathy. After immunotherapy (steroids and cyclosporine), the massive prote...
Source: Clinical Nephrology - August 7, 2023 Category: Urology & Nephrology Authors: Kunxiao Zhao Lin Ruan Zheli Niu Qiongzhen Lin Source Type: research
