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Specialty: Geriatrics
Condition: Diabetes Mellitus

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Total 63 results found since Jan 2013.

Associations Between Oral Health and Risk of Dementia in a 37‐Year Follow‐Up Study: The Prospective Population Study of Women in Gothenburg
ConclusionIn most of the analyses, lower tooth count was not associated with dementia, although a significant association was found for one of the three examinations. Further research may benefit from more‐direct measures of dental and periodontal disease.
Source: Journal of the American Geriatrics Society - January 17, 2015 Category: Geriatrics Authors: Robert Stewart, Ulrika Stenman, Magnus Hakeberg, Catharina Hägglin, Deb Gustafson, Ingmar Skoog Tags: Brief Reports Source Type: research

Risk factors for incident dementia after stroke and transient ischemic attack
Conclusions Chronic brain changes including WMCs, MTLA, and AD pathology are associated with incident dementia after stroke/TIA. Interventions targeting these chronic brain changes may reduce burden of vascular cognitive impairment.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - January 17, 2015 Category: Geriatrics Source Type: research

Prolonged risk of subtrochanteric and diaphyseal femur fractures after discontinuing alendronate treatment: A nationwide nested case-control study in Taiwan
Conclusion Discontinuation of alendronate therapy did not reduce the risk of subtrochanteric femoral fractures until it was discontinued for >5 years. In conclusion, alendronate use significantly increased the risk of subtrochanteric femoral fractures, and the risk may persist for 5 years after discontinuation.
Source: Journal of Clinical Gerontology and Geriatrics - November 27, 2014 Category: Geriatrics Source Type: research

Development and validation of a brief dementia screening indicator for primary care
Conclusions The Dementia Screening Indicator is a simple tool that may be useful in primary care settings to identify high-risk patients to target for cognitive screening.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 19, 2014 Category: Geriatrics Source Type: research

Statin Discontinuation in Nursing Home Residents with Advanced Dementia
ConclusionMost NH residents who use statins at the time of progression to advanced dementia continue use in follow‐up.
Source: Journal of the American Geriatrics Society - November 4, 2014 Category: Geriatrics Authors: Jennifer Tjia, Sarah L. Cutrona, Daniel Peterson, George Reed, Susan E. Andrade, Susan L. Mitchell Tags: Clinical Investigations Source Type: research

Midlife stroke risk and cognitive decline: A 10-year follow-up of the Whitehall II cohort study
Conclusion Elevated stroke risk at midlife is associated with accelerated cognitive decline over 10 years. Aggregation of risk factors may be especially important in this association.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - October 24, 2014 Category: Geriatrics Source Type: research

One‐Year Mortality in Elderly Adults with Non‐ST‐Elevation Acute Coronary Syndrome: Effect of Diabetic Status and Admission Hyperglycemia
ConclusionIn elderly adults with NSTEACS, diabetes mellitus and hyperglycemia on admission are associated with higher mortality, mostly because of preexisting cardiovascular and renal damage.
Source: Journal of the American Geriatrics Society - June 10, 2014 Category: Geriatrics Authors: Stefano Savonitto, Nuccia Morici, Claudio Cavallini, Roberto Antonicelli, Anna Sonia Petronio, Ernesto Murena, Zoran Olivari, Giuseppe Steffenino, Francesco Bonechi, Antonio Mafrici, Anna Toso, Federico Piscione, Leonardo Bolognese, Stefano De Servi Tags: Clinical Investigations Source Type: research

Midlife stroke risk and cognitive decline
Kaffashian et al. [1] presented the results of the long-term follow up of a large cohort study concerning the higher risk of cognitive decline in patients with higher risk of stroke. This last feature was synthesized by the score of the Framingham Stroke Risk Profile (FSRP), which has been studied in the past also to predict cognitive performance in middle-aged adults and elderly. A first finding of the study was the absence of an association between cognitive changes and single vascular risk factors, with the exception of diabetes mellitus and in line with previous studies [2].
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - April 7, 2014 Category: Geriatrics Authors: Simone Vidale Source Type: research

Prevention of poststroke apathy using escitalopram or problem-solving therapy.
CONCLUSION: Escitalopram or PST was significantly more effective in preventing new onset of apathy following stroke compared with placebo. PMID: 23930743 [PubMed - in process]
Source: Am J Geriatr Psychia... - August 13, 2013 Category: Geriatrics Authors: Mikami K, Jorge RE, Moser DJ, Arndt S, Jang M, Solodkin A, Small SL, Fonzetti P, Hegel MT, Robinson RG Tags: Am J Geriatr Psychiatry Source Type: research

Proteomic Analysis of Mature Adipocytes from Obese Patients in Relation to Aging.
In conclusion, proteomic analysis of subcutaneous adipose tissue reveals differences in the abundance of proteins in adipocytes isolated from young vs. old individuals. These differentially abundant proteins are involved in the regulation of apoptosis, cellular senescence and inflammatory response. All these are common pathologic events in both obesity and aging. PMID: 23886751 [PubMed - as supplied by publisher]
Source: Experimental Gerontology - July 22, 2013 Category: Geriatrics Authors: Alfadda AA, Benabdelkamel H, Masood A, Moustafa A, Sallam R, Bassas A, Duncan M Tags: Exp Gerontol Source Type: research

Prestroke Factors Associated with Poststroke Mortality and Recovery in Older Women in the Women's Health Initiative
ConclusionPotentially modifiable factors before stroke, including smoking, diabetes mellitus, and being underweight, were associated with greater poststroke mortality in older women. Being overweight or obese and physical activity before stroke were associated with lower poststroke mortality in older women.
Source: Journal of the American Geriatrics Society - July 19, 2013 Category: Geriatrics Authors: Christina L. Bell, Andrea LaCroix, Kamal Masaki, Erinn M. Hade, Todd Manini, W. Jerry Mysiw, Jess David Curb, Sylvia Wassertheil‐Smoller Tags: Brief Reports Source Type: research

Stroke‐Associated Differences in Rates of Activity of Daily Living Loss Emerge Years Before Stroke Onset
ConclusionIn adults at risk of stroke, disproportionate ADL limitations emerge well before stroke onset. Excess disability in stroke survivors should not be entirely attributed to effects of acute stroke or quality of acute stroke care. Although there are many possible causal pathways between ADL and stroke, the association may be noncausal. For example, ADL limitations may be a consequence of stroke risk factors (e.g., diabetes mellitus) or early cerebrovascular ischemia.
Source: Journal of the American Geriatrics Society - May 13, 2013 Category: Geriatrics Authors: Benjamin D. Capistrant, Qianyi Wang, Sze Y. Liu, M. Maria Glymour Tags: Clinical Investigations Source Type: research

Optimal Blood Pressure for Cognitive Function: Findings from an Elderly African‐American Cohort Study
ConclusionHigh and low BP were associated with poorer cognitive performance. A joint optimal region of SBP and DBP for cognitive function has been identified, which may provide useful clinical information on optimal BP control in cognitive health and lead to better quality of life for elderly adults.
Source: Journal of the American Geriatrics Society - May 6, 2013 Category: Geriatrics Authors: Hai Liu, Sujuan Gao, Kathleen S. Hall, Frederick W. Unverzagt, Kathleen A. Lane, Christopher M. Callahan, Hugh C. Hendrie Tags: Clinical Investigations Source Type: research

Stroke in centenarians
ConclusionCentenarians with stroke are from a cardiovascular standpoint healthier than their younger counterparts. Yet, strokes in centenarians are more severe and associated with very high mortality. Geriatr Gerontol Int 2013; ●●: ●●–●●.
Source: Geriatrics and Gerontology International - March 26, 2013 Category: Geriatrics Authors: Tom Skyhøj Olsen, Klaus Kaae Andersen Tags: ORIGINAL ARTICLE Source Type: research

Depressive symptoms as an independent risk factor for mortality in elderly persons: Results of a national longitudinal study.
Conclusion: Depressive symptoms are an independent risk factor for mortality in the elderly. Elderly depressive men and elderly without chronic diseases seemed to have a greater mortality risk. PMID: 23215855 [PubMed - as supplied by publisher]
Source: Aging and Mental Health - December 7, 2012 Category: Geriatrics Authors: Teng PR, Yeh CJ, Lee MC, Lin HS, Lai TJ Tags: Aging Ment Health Source Type: research