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Specialty: Geriatrics
Condition: Dementia

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Total 327 results found since Jan 2013.

Effects of a Rivastigmine Patch on Self-Care Activities in Patients with Alzheimer's Disease plus Cerebrovascular Disease
Background/Aims: In dementia patients, a deficit in activities of daily living (ADL) is one of the main problems. Our objective was to assess ADL using the Korean Modified Barthel Index (K-MBI) in patients with Alzheimer's disease (AD) plus cerebrovascular disease (CVD) treated with a rivastigmine patch for 24 weeks in an open-label, observational study. Methods: 29 patients were enrolled who met the National Institute of Neurological and Communicative Disorders and Stroke/Alzheimer's Disease and Related Disorders Association (NINCDS/ ANDRA) criteria and had a score of 10-26 on the Korean version of the Mini-Mental State E...
Source: Dementia and Geriatric Cognitive Disorders Extra - November 6, 2014 Category: Geriatrics Source Type: research

Retinal Vascular Fractals and Cognitive Impairment
Conclusion: A sparser retinal microvascular network, represented by reduced arteriolar and venular fractal dimensions, was associated with cognitive impairment, suggesting that early microvascular damage may be present in preclinical stages of dementia.Dement Geriatr Cogn Disord Extra 2014;4:305-313
Source: Dementia and Geriatric Cognitive Disorders Extra - November 6, 2014 Category: Geriatrics Source Type: research

Statin Discontinuation in Nursing Home Residents with Advanced Dementia
ConclusionMost NH residents who use statins at the time of progression to advanced dementia continue use in follow‐up.
Source: Journal of the American Geriatrics Society - November 4, 2014 Category: Geriatrics Authors: Jennifer Tjia, Sarah L. Cutrona, Daniel Peterson, George Reed, Susan E. Andrade, Susan L. Mitchell Tags: Clinical Investigations Source Type: research

Physical activity in the elderly is associated with improved executive function and processing speed: the LADIS Study
ConclusionOur findings confirm previous findings of a positive effect of physical activity on cognitive functions in elderly subjects, and further extends these by showing that the association is also present in patients with ARWMC. Copyright © 2014 John Wiley & Sons, Ltd.
Source: International Journal of Geriatric Psychiatry - November 3, 2014 Category: Geriatrics Authors: Kristian Steen Frederiksen, Ana Verdelho, Sofia Madureira, Hansjörg Bäzner, John T. O'Brien, Franz Fazekas, Philip Scheltens, Reinhold Schmidt, Anders Wallin, Lars‐Olof Wahlund, Timo Erkinjunttii, Anna Poggesi, Leonardo Pantoni, Domenico Inzitari, Gun Tags: Research Article Source Type: research

Midlife stroke risk and cognitive decline: A 10-year follow-up of the Whitehall II cohort study
Conclusion Elevated stroke risk at midlife is associated with accelerated cognitive decline over 10 years. Aggregation of risk factors may be especially important in this association.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - October 24, 2014 Category: Geriatrics Source Type: research

2014 Alzheimer's disease facts and figures
This report discusses the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality rates, costs of care, and overall effect on caregivers and society. It also examines the impact of AD on women compared with men. An estimated 5.2 million Americans have AD. Approximately 200,000 people younger than 65 years with AD comprise the younger onset AD population; 5 million are age 65 years or older. By mid-century, fueled in large part by the baby boom generation, the number of people living with AD in the United States is projected to grow by about 9 million. Today, someone in the country d...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - October 17, 2014 Category: Geriatrics Source Type: research

2013 Alzheimer's disease facts and figures
This report provides information to increase understanding of the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality rates, health expenditures and costs of care, and effect on caregivers and society in general. It also explores the roles and unique challenges of long-distance caregivers, as well as interventions that target those challenges. An estimated 5.2 million Americans have AD. Approximately 200,000 people younger than 65 years with AD comprise the younger onset AD population; 5 million comprise the older onset AD population. Throughout the coming decades, the baby boom ...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - October 17, 2014 Category: Geriatrics Source Type: research

Observational assessment of communication disorders in vascular dementia patients with right hemisphere damage
ConclusionWe believe that communication disorder in the RBD patients may be evaluated with the DCAS. We plan to standardize the DCAS and apply it for use in rehabilitation in the future.
Source: Psychogeriatrics - September 1, 2014 Category: Geriatrics Authors: Miyuki Kawada, Naofumi Tanaka, Satoshi Yamaguchi, Kenichi Meguro Tags: ORIGINAL ARTICLE Source Type: research

Gastritis May Boost Odds of Dementia
Conclusions: The findings from this population-based observational study showing evidence that gastritis may increase the risk of dementia provide avenue for further inquiries into dementia.
Source: American Journal of Alzheimer's Disease and Other Dementias - July 15, 2014 Category: Geriatrics Authors: Momtaz, Y. A., Hamid, T. A., Ibrahim, R. Tags: Current Topics in Research Source Type: research

Aggregate effects of vascular risk factors on cerebrovascular changes in autopsy-confirmed Alzheimer's disease
We examined the relationships of antemortem vascular risk factors to postmortem cerebrovascular and Alzheimer's disease (AD) pathologies. Eighty-four AD patients underwent an assessment of vascular risk (blood pressure, cholesterol, smoking, cardiovascular disease, diabetes, atrial fibrillation, transient ischemic attack [TIA], or stroke) and later underwent brain autopsy. Given our aim to examine mild cerebrovascular changes (CVCs), individuals were excluded if autopsy revealed large stroke. The most common forms of CVC were circle of Willis atherosclerosis followed by arteriosclerosis, lacunes, and microinfarcts.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - July 8, 2014 Category: Geriatrics Authors: Katherine J. Bangen, Daniel A. Nation, Lisa Delano-Wood, Gali H. Weissberger, Lawrence A. Hansen, Douglas R. Galasko, David P. Salmon, Mark W. Bondi Source Type: research

Call for new policy focus on brain health to reduce the risk of dementia
Action to tackle smoking, drinking, sedentary behaviour and poor diet could reduce the risk of dementia in later life alongside other conditions such as heart disease, stroke and many cancers.
Source: Alzheimers Society - May 23, 2014 Category: Geriatrics Source Type: news

Midlife stroke risk and cognitive decline
Kaffashian et al. [1] presented the results of the long-term follow up of a large cohort study concerning the higher risk of cognitive decline in patients with higher risk of stroke. This last feature was synthesized by the score of the Framingham Stroke Risk Profile (FSRP), which has been studied in the past also to predict cognitive performance in middle-aged adults and elderly. A first finding of the study was the absence of an association between cognitive changes and single vascular risk factors, with the exception of diabetes mellitus and in line with previous studies [2].
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - April 7, 2014 Category: Geriatrics Authors: Simone Vidale Source Type: research

Detection of Early Cognitive Impairment Using AD8 in a Young Patient With Stroke With Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Syndrome: A Case Report
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) syndrome is a hereditary disease resulting from NOTCH3 gene mutation. The clinical presentations include migraine, recurrent stroke, and cognitive impairment. The severity of cognitive impairment varies in different stages, and early recognition poses a challenge. A 47-year-old lady presented with chronic migraine and sudden onset of hemiparesis. Magnetic resonance imaging revealed compatible findings of CADASIL, which was confirmed by mutation analysis of NOTCH3 gene. Early cognitive impairment was detected by her score of...
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Hsieh, I.-C., Kuan, T.-S., Hsieh, P.-C., Chen, S.-M., Yen, W.-J., Chang, W.-C., Lin, I.-L., Lin, Y.-C. Tags: Current Topics in Care Source Type: research

Risk factors for incident dementia after stroke and transient ischemic attack
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 3, 2014 Category: Geriatrics Authors: Jie Yang, Adrian Wong, Zhaolu Wang, Wenyan Liu, Lisa Au, Yunyun Xiong, Winnie W.C. Chu, Eric Y.L. Leung, Sirong Chen, Christine Lau, Anne Y.Y. Chan, Alexander Y.L. Lau, Florence Fan, Vincent Ip, Yannie Soo, Thomas Leung, Chi L. Ho, Lawrence K.S. Wong, Vin Source Type: research