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Specialty: Drugs & Pharmacology
Condition: Dementia
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Total 176 results found since Jan 2013.
Strategies for treatment of disease-associated dementia beyond Alzheimer disease: An update
Curr Neuropharmacol. 2022 Apr 11. doi: 10.2174/1570159X20666220411083922. Online ahead of print.ABSTRACTMemory, cognition, dementia, and neurodegeneration are complexly interlinked processes through various mechanistic pathways leading to a range of clinical outcomes. These are strongly associated with pathological conditions like Alzheimer's disease, Parkinson's disease, schizophrenia, stroke and are a growing concern for their timely diagnosis and management. Several cognition-enhancing interventions for management include non-pharmacological interventions like diet, exercise, and physical activity, while pharmacological...
Source: Current Neuropharmacology - April 12, 2022 Category: Drugs & Pharmacology Authors: Khan Sabiya Samim Gopal L Khatik Ashok K Datusalia Source Type: research
Current Trends in the Animal Models for Screening of Nootropic Agents
CONCLUSION: Since a variety of etiologies can affect the cognitive processes, hence a nootropic agent may be screened in a variety of disease models. The most widely used and appropriate method to assess cognition would be by combining the behavioral and biochemical assays so that a more comprehensive profile about the nootropic effects of a drug can be elicited.PMID:35469584 | DOI:10.2174/2772432817666220425121323
Source: Pharmacological Reviews - April 26, 2022 Category: Drugs & Pharmacology Authors: Shubhima Grover Seema Jain Source Type: research
NeuroProtect, a Candidate Formula From Traditional Chinese Medicine, Attenuates Amyloid- β and Restores Synaptic Structures in APP/PS1 Transgenic Mice
Conclusion: These findings reveal a beneficial effect of NP on AD progression under an early intervention strategy and provide a food supplement for AD prevention.
Source: Frontiers in Pharmacology - May 2, 2022 Category: Drugs & Pharmacology Source Type: research
Effects of chronic vagal nerve stimulation in the treatment of β-AMYLOID induced neuropsychiatric symptoms
In conclusion, VNS could be an effective treatment of NPSs, especially depression and anxiety, in AD patients without impairing cognition.PMID:35973478 | DOI:10.1016/j.ejphar.2022.175179
Source: European Journal of Pharmacology - August 16, 2022 Category: Drugs & Pharmacology Authors: Metin Yesiltepe Bariscan Cimen Yildirim Sara Source Type: research
A literature review of hypertensive retinopathy: systemic correlations and new technologies
CONCLUSIONS: The eye is the only organ in the human body where changes in the blood vessels due to systemic hypertension can be studied in vivo. All doctors should be familiar with this disease because it has been largely demonstrated that signs of HR are correlated to patient's health and mortality. Researchers should develop a new common, standardized, and objective method to assess hypertensive retinal changes; new technologies may have a significant role in this field. This review takes most of the literature published so far, including the OCTA studies in order to stimulate new points of reference to standardize param...
Source: Pharmacological Reviews - October 5, 2022 Category: Drugs & Pharmacology Authors: E Di Marco F Aiello M Lombardo M Di Marino F Missiroli R Mancino F Ricci C Nucci A Noce N Di Daniele M Cesareo Source Type: research
