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Specialty: Neurology
Condition: Dementia

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Total 1006 results found since Jan 2013.

Cognitive Dysfunction in Stroke Survivors: A Community-Based Prospective Study from Kolkata, India
The frequency of cognitive dysfunction among community stroke survivors (SS) is not known in India. This prospective study investigated the prevalence of poststroke mild cognitive impairment (psMCI) and poststroke dementia (psDem), the annual progression rate to dementia, and pertinent risk factors in a sample population of SS in Kolkata, India between September 2006 and July 2010. From a community-based stroke registry, 281 SS were assessed at baseline year after excluding attrition due to various causes. Validated cognitive tools were applied by trained field workers under supervision of a neuropsychologist. The assessme...
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2012 Category: Neurology Authors: Sujata Das, Neelanjana Paul, Avijit Hazra, Malay Ghosal, Biman Kanti Ray, Tapas Kumar Banerjee, Prabir Burman, Shyamal Kumar Das Tags: Original Articles Source Type: research

Thrombolytic therapy for stroke in patients with preexisting cognitive impairment
Conclusions: Ischemic stroke patients with PSCI should receive rtPA if they are eligible. This conclusion cannot be extended to severe cognitive impairment or severe strokes. Classification of evidence: This study provides Class IV evidence that in patients with PSCI presenting with acute ischemic stroke, IV rtPA improves outcomes.
Source: Neurology - June 9, 2014 Category: Neurology Authors: Murao, K., Leys, D., Jacquin, A., Kitazono, T., Bordet, R., Bejot, Y., Kimura, K., Godefroy, O., Wakisaka, Y., Moulin, S., Ago, T., Sibon, I., Bombois, S., Mas, J.-L., Henon, H., Pasquier, F., Giroud, M., Cordonnier, C., Okada, Y., On behalf of the OPHELI Tags: All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, MCI (mild cognitive impairment), Infarction ARTICLE Source Type: research

Montreal Cognitive Assessment 5-Minute Protocol Is a Brief, Valid, Reliable, and Feasible Cognitive Screen for Telephone Administration Clinical Sciences
Conclusions— The MoCA 5-minute protocol is a free, valid, and reliable cognitive screen for stroke and transient ischemic attack. It is brief and highly feasible for telephone administration.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Wong, A., Nyenhuis, D., Black, S. E., Law, L. S. N., Lo, E. S. K., Kwan, P. W. L., Au, L., Chan, A. Y. Y., Wong, L. K. S., Nasreddine, Z., Mok, V. Tags: Behavioral/psychosocial - stroke Clinical Sciences Source Type: research

Impact of Bilingualism on Cognitive Outcome After Stroke Brief Reports
Conclusions— Our results suggest that bilingualism leads to a better cognitive outcome after stroke, possibly by enhancing cognitive reserve.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Alladi, S., Bak, T. H., Mekala, S., Rajan, A., Chaudhuri, J. R., Mioshi, E., Krovvidi, R., Surampudi, B., Duggirala, V., Kaul, S. Tags: Lifestyle, Behavioral/Psychosocial Treatment, Quality and Outcomes, Cognitive Impairment Brief Reports Source Type: research

Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia Clinical Sciences
Conclusions— Adherence to the American Heart Association’s ideal CVH factors and behaviors, particularly in midlife, may protect against cerebrovascular disease and dementia.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Pase, M. P., Beiser, A., Enserro, D., Xanthakis, V., Aparicio, H., Satizabal, C. L., Himali, J. J., Kase, C. S., Vasan, R. S., DeCarli, C., Seshadri, S. Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Cognitive Impairment Clinical Sciences Source Type: research

Design and Rationale for a Cognitive Outcome Substudy in Ischemic Stroke Patients with High Risk of Cerebral Hemorrhage
Cognitive impairment and dementia are common disabilities after stroke and are associated with increased risks of mortality and recurrent stroke. The prevention of dementia and preserving cognitive function are also important in stroke patients, but its strategy is not established yet. This PICASSO-COG (PreventIon of CArdiovascular events in iSchemic Stroke patients with high risk of cerebral hemOrrhage for reducing COGnitive decline) substudy aims to assess the effects of cilostazol and/or probucol on cognitive function.
Source: Journal of Stroke and Cerebrovascular Diseases - May 31, 2016 Category: Neurology Authors: Kyung-Ho Yu, Keun-Sik Hong, Mi-Sun Oh, Juneyoung Lee, Ji Sung Lee, Sun U. Kwon, PICASSO investigators Source Type: research

Endovascular treatment improves cognition after stroke: A secondary analysis of REVASCAT trial
Conclusions: Thrombectomy improves TMT performance after stroke, especially among patients who reach good functional recovery. ClinicalTrials.gov identifier: NCT01692379. Classification of evidence: This study provides Class I evidence that for patients with stroke from acute anterior circulation proximal arterial occlusion, thrombectomy improves performance on the TMT at 3 months.
Source: Neurology - January 15, 2017 Category: Neurology Authors: Lopez-Cancio, E., Jovin, T. G., Cobo, E., Cerda, N., Jimenez, M., Gomis, M., Hernandez-Perez, M., Caceres, C., Cardona, P., Lara, B., Renu, A., Llull, L., Boned, S., Muchada, M., Davalos, A. Tags: Prognosis, All Cerebrovascular disease/Stroke, Clinical trials Randomized controlled (CONSORT agreement), Infarction ARTICLE Source Type: research

Admission Brain Cortical Volume Clinical Sciences
Conclusions—Smaller cortical volumes in fronto-temporo-insular areas measured 24 to 72 hours post stroke are associated with cognitive vulnerability in the subacute stroke phase.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Sharmila Sagnier, Gwenaelle Catheline, Bixente Dilharreguy, Fanny Munsch, Antoine Bigourdan, Mathilde Poli, Sabrina Debruxelles, Stephane Olindo, Pauline Renou, Francois Rouanet, Vincent Dousset, Thomas Tourdias, Igor Sibon Tags: Magnetic Resonance Imaging (MRI), Cognitive Impairment, Ischemic Stroke Original Contributions Source Type: research

Prevalence of Poststroke Neurocognitive Disorders Using National Institute of Neurological Disorders and Stroke-Canadian Stroke Network, VASCOG Criteria (Vascular Behavioral and Cognitive Disorders), and Optimized Criteria of Cognitive Deficit Clinical Sciences
Conclusions—This study is the first to have optimized the operationalization of the criterion for poststroke cognitive impairment. It documented the prevalence of poststroke NCD in the GRECOG-VASC cohort and showed that mild cognitive impairment accounts for 80% of the affected patients. Finally, the method developed in the present study offers a means of harmonizing the diagnosis of NCD.Clinical Trial Registration—URL: https://www.clinicaltrials.gov. Unique identifier: NCT01339195.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Melanie Barbay, Herve Taillia, Claudine Nedelec–Ciceri, Flavie Bompaire, Camille Bonnin, Jerome Varvat, Francoise Grangette, Momar Diouf, Emmanuel Wiener, Jean–Louis Mas, Martine Roussel, Olivier Godefroy Tags: Cognitive Impairment Original Contributions Source Type: research

Association of Blood Pressure and Cognition after Stroke
We examined associations between systolic and diastolic BP (SBP, DBP), pulse pressure (PP), mean arterial pressure (MAP), and cognition, each measured 90 days after stroke. Methods: Cross-sectional analysis of prospectively obtained data of 432 dementia-free subjects greater than or equal to 45 (median age, 66; 45% female) with stroke (92% ischemic; median NIH stroke score, 3 [IQR, 2-6]) from the population-based Brain Attack Surveillance in Corpus Christi (BASIC) project in 2011-2013.
Source: Journal of Stroke and Cerebrovascular Diseases - May 2, 2020 Category: Neurology Authors: Deborah A. Levine, Andrzej T. Galecki, Dolorence Okullo, Emily M. Brice ño, Mohammed U. Kabeto, Lewis B. Morgenstern, Kenneth M. Langa, Bruno Giordani, Robert Brook, Brisa N. Sanchez, Lynda D. Lisabeth Source Type: research

Association Between Oral Anticoagulants and Stroke Severity at Onset in Elderly Patients with Cardioembolic Stroke Due to Non-Valvular Atrial Fibrillation
The prevention of cardioembolic stroke is an important public health priority in Japan due to its high prevalence in elderly individuals. Compared to their younger counterparts, elderly patients with cardioembolic stroke are more likely to have multiple comorbidities, a higher risk of serious complications, such as pneumonia and heart failure, and cognitive impairments (e.g., dementia or delirium), which may adversely affect their ability to participate in active rehabilitation. These factors negatively affect clinical outcomes, and many elderly stroke survivors require long-term care despite the early implementation of intensive therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - December 25, 2021 Category: Neurology Authors: Ichiro Deguchi, Takashi Osada, Shinichi Takahashi Source Type: research

A quantitative systematic review of domain-specific cognitive impairment in lacunar stroke
Conclusions: Results of this systematic review are consistent with previous characterizations of cognitive impairment associated with lacunar strokes. However, impaired cognition in this stroke subtype appears less selective than previously thought, involving all major cognitive domains.
Source: Neurology - January 14, 2013 Category: Neurology Authors: Edwards, J. D., Jacova, C., Sepehry, A. A., Pratt, B., Benavente, O. R. Tags: Other cerebrovascular disease/ Stroke, Clinical neurology examination, Neuropsychological assessment, Assessment of cognitive disorders/dementia VIEWS & amp;amp; REVIEWS Source Type: research

Incidence of stroke in people with Alzheimer disease: A national register-based approach
Conclusions: Our findings suggest that persons with AD dementia, especially younger patients, have higher risk of hemorrhagic strokes.
Source: Neurology - January 21, 2013 Category: Neurology Authors: Tolppanen, A.-M., Lavikainen, P., Solomon, A., Kivipelto, M., Soininen, H., Hartikainen, S. Tags: All Cerebrovascular disease/Stroke, Alzheimer's disease, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Poststroke hip fracture: prevalence, clinical characteristics, mineral-bone metabolism, outcomes, and gaps in prevention.
Conclusions. Approximately one in seven HFs occurs in older stroke survivors and are associated with poorer outcomes. Early implementation of fracture prevention strategies is needed. PMID: 24187647 [PubMed]
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research