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Condition: Dementia
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Total 3025 results found since Jan 2013.
Occupational therapy for persons with cognitive impairments
CONCLUSIONS: Based on this systematic overview, it can neither be proven nor excluded with certainty that occupational therapy for cognitive impairment is an effective therapy for adult patients with central nervous system injuries compared to no occupational therapy. There is a lack of randomised trials with sufficient sample size, well-defined interventions, and comparable concomitant therapies in the control groups, but there is also a lack of well-designed observational studies in routine care and health economic studies. The identified systematic reviews on patient and social aspects provide information on the needs o...
Source: GMS German Medical Science - June 1, 2023 Category: General Medicine Authors: Petra Schnell-Inderst Annette Conrads-Frank Igor Stojkov Cornelia Krenn Lisa-Maria Kofler Uwe Siebert Source Type: research
Heart Attack Linked to Faster Cognitive Decline Over Time, Study Suggests
Individuals who experience a myocardial infarction (heart attack) appear to have a faster cognitive decline over time than those who do not experience a myocardial infarction, according to areport published yesterday inJAMA Neurology.The findings point to the importance of tracking the cognitive function of patients who have experienced a myocardial infarction and suggest that high-risk patients should be counseled on the potential cognitive ramifications of such an event, wrote lead author Michelle C. Johansen, M.D., Ph.D., of Johns Hopkins University and colleagues. “The findings also suggest that p...
Source: Psychiatr News - May 31, 2023 Category: Psychiatry Tags: cognition executive function heart attack JAMA Neurology memory Source Type: research
Association Between Acute Myocardial Infarction and Cognition
CONCLUSIONS: This cohort study using pooled data from 6 cohort studies found that incident MI was not associated with a decrease in global cognition, memory, or executive function at the time of the event compared with no MI but was associated with faster declines in global cognition, memory, and executive function over time. These findings suggest that prevention of MI may be important for long-term brain health.PMID:37252710 | DOI:10.1001/jamaneurol.2023.1331
Source: Atherosclerosis - May 30, 2023 Category: Cardiology Authors: Michelle C Johansen Wen Ye Alden Gross Rebecca F Gottesman Dehua Han Rachael Whitney Emily M Brice ño Bruno J Giordani Supriya Shore Mitchell S V Elkind Jennifer J Manly Ralph L Sacco Alison Fohner Michael Griswold Bruce M Psaty Stephen Sidney Jeremy Sus Source Type: research
Cytochrome P450-derived eicosanoids in brain: From basic discovery to clinical translation
Adv Pharmacol. 2023;97:283-326. doi: 10.1016/bs.apha.2022.11.002. Epub 2023 Jan 11.ABSTRACTCytochrome P450 metabolism of arachidonic acid produces epoxyeicosatrienoates (EETs) and hydroxyeicosatetraenoates (HETEs). Both classes of eicosanoids play important and opposing roles in brain function and disease. EETs promote vasodilation and exhibit antiinflammatory and cytoprotective properties; their biological action is blunted by metabolism to less active diols by the enzyme soluble epoxide hydrolase (sEH). EETs levels are dysregulated in disease states, primarily due to increased activity of sEH. Inhibition of sEH is a prom...
Source: Advances in Pharmacology - May 26, 2023 Category: Drugs & Pharmacology Authors: Catherine M Davis Aseel H Ibrahim Nabil J Alkayed Source Type: research
