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Condition: Dementia
Education: Education

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Total 430 results found since Jan 2013.

APOE and mild cognitive impairment: the Framingham Heart Study
Conclusion: APOE4 risk for prevalent amnestic MCI varies depending on the definition of objective neuropsychological impairment for MCI. Our findings support existing literature emphasising the need to refine MCI neuropsychological profiling methods.
Source: Age and Ageing - February 23, 2015 Category: Geriatrics Authors: Jefferson, A. L., Beiser, A. S., Seshadri, S., Wolf, P. A., Au, R. Tags: Research Papers Source Type: research

What 'Empire' Got Right (And Wrong) About Music Therapy
Perhaps one of the most stirring and sympathetic characters in Fox’s hit show “Empire" is Andre, who suffers from Bipolar disorder. In case you’ve been living under a rock for the past three months and haven’t watched the hottest TV show of 2015, here’s a quick recap of Andre’s situation: the oldest son of a music conglomerate CEO vies for power over the company he helped build, but between all the pressure (and betrayal, and violence, and lack of love and support), as well as his attempts to keep a lid on his emotions, Andre eventually flushes his meds down the toilet, precipitating a mental breakdown and entr...
Source: Healthy Living - The Huffington Post - March 19, 2015 Category: Consumer Health News Source Type: news

Physical activity, motor function, and white matter hyperintensity burden in healthy older adults
Conclusions: Higher levels of physical activity may reduce the effect of WMH burden on motor function in healthy older adults.
Source: Neurology - March 30, 2015 Category: Neurology Authors: Fleischman, D. A., Yang, J., Arfanakis, K., Arvanitakis, Z., Leurgans, S. E., Turner, A. D., Barnes, L. L., Bennett, D. A., Buchman, A. S. Tags: MRI, All Clinical Neurology, All Cerebrovascular disease/Stroke, Motor Control, Cohort studies ARTICLE Source Type: research

Healthy diet could cut risk of Alzheimer's disease
ConclusionThe study found people who ate a healthy diet – with plenty of green vegetables, wholegrains, legumes and less red meat – may be less likely to get Alzheimer's disease. However, we should be wary of saying that their diet actually protected them from Alzheimer's, as it is a complex disease with many potential causes.The main limitation is that observational studies cannot prove causation, even when researchers take care, as they did here, to include factors that we know affect disease risk. It's also notable that the researchers excluded dementia, other than Alzheimer's disease, from their calculations. It wo...
Source: NHS News Feed - March 31, 2015 Category: Consumer Health News Tags: Food/diet Neurology Source Type: news

Demographics, Comorbidities and Clinical Features in Hospitalized Patients with Myoclonus (P3.022)
CONCLUSIONS: Myoclonus was particularly associated with renal impairment in the presence of a toxic exposure, most commonly opioids or anticonvulsants, and unlike patients with anoxia or hepatic impairment, more often featured a negative semiology.Disclosure: Dr. Ehrlich has nothing to disclose. Dr. Swan has nothing to disclose. Dr. Robbins has received personal compensation for activities with MedLink and Prova Education. Dr. Robbins has received personal compensation in an editorial capacity for Current Pain and Headache Reports. Dr. Herskovitz has nothing to disclose. Dr. Milstein has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ehrlich, D., Swan, M., Robbins, M., Herskovitz, S., Milstein, M. Tags: Movement Disorders: Myoclonus, Paroxysmal Dyskinesias, and Parkinson ' s Disease Source Type: research

Demographics and Impact on Diagnosis of Neurological Consultations in the ICU (P5.035)
CONCLUSIONS: The neurology consult service had a measurable impact on diagnosis in ICU patients, changing the diagnosis in 75[percnt], and may, therefore, make an important contribution to management and outcomes of these patients.Disclosure: Dr. Weathered has nothing to disclose. Dr. Lennihan has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Weathered, N., Lennihan, L. Tags: Neuroepidemiology: Aging, Dementia, Cognitive, and Behavioral Neurology, General Neurology, and Research Methodology and Education Source Type: research

An Unusual Case Of Cadasil With Occipital Lobe Involvement (P6.006)
CONCLUSION: We discuss the unique features of a rare case of occipital lobe predominant CADASIL lacking the typical anterior temporal lobe involvement. This case exemplifies the heterogeneity of clinical findings that may be associated with NOTCH3 mutations.Disclosure: Dr. Mishra has nothing to disclose. Dr. Rao has nothing to disclose. Dr. Flippen has received personal compensation for activities with MAP Pharmaceuticals/Allergan. Dr. Flippen has received personal compensation in an editorial capacity for the Journal of Graduate Medical Education and Up-To-Date. Dr. Flippen has received Dr. Fogel has received personal com...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Mishra, S., Rao, N., Flippen, C., Fogel, B., Hathout, G., Thomas, M., Kattan, J., Trikamji, B. Tags: Treatments, Therapeutics, and Biomarkers Poster Discussion Session Source Type: research

Genetic Association Study of Cognitive Performance (P6.209)
CONCLUSIONS: SORL1 encodes an apolipoprotein E receptor, and influences cognitive decline. Decreased expression of SORL1 has been associated with Alzheimer’s disease. Our data support SNPs rs2101756 and rs985421 as possible moderators of age-related episodic memory decline. Study Supported by: NINDS R37 NS029993, Evelyn F. McKnight Brain Institute, ACMG FoundationDisclosure: Dr. Katz has nothing to disclose. Dr. Dong has nothing to disclose. Dr. Stern has received personal compensation for activities with Elan, Bayer Pharmaceuticals Corporation, Cephalon, and GalaxoSmithKlein as a consultant. Dr. Wright has received ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Katz, J., Dong, C., Stern, Y., Wright, C., Blanton, S., Sacco, R. Tags: Aging, Dementia, Cognitive, and Behavioral Neurology: Cognition and Cognitive Assessment Source Type: research

Using Big data for an Economic Evaluation of reducing the Innappropriate prescribing of atypical Antipsychotics among Dementia Patients
This study is an economic evaluation of the NPS MedicineWise educational program in terms of reduced falls and stroke incidence due to reduction in antipsychotic prescribing including olanzapine, quetiapine and risperidone
Source: Value in Health - May 1, 2015 Category: Global & Universal Authors: R. Khan, A. Jammali-Blasi, A. Todkar, A. Heaney Source Type: research

Stability of Diagnoses of Cognitive Impairment, Not Dementia in a Veterans Affairs Primary Care Population
ConclusionA minority of subjects had worsening of cognitive function sufficient to change diagnostic category. Over an average of 2.5 years, subjects diagnosed with CIND at baseline reverted to normal cognition at a higher rate than progressed to dementia. Cognitive screening tests addressing multiple domains of cognitive impairment were predictive of cognitive decline.
Source: Journal of the American Geriatrics Society - June 1, 2015 Category: Geriatrics Authors: Tracey Holsinger, Brenda L. Plassman, Karen M. Stechuchak, James R. Burke, Cynthia J. Coffman, John W. Williams Tags: Clinical Investigations Source Type: research

Five-year 'death test' for older adults launched online
Conclusion This large study has identified numerous risk factors associated with a person's risk of death within five years. Researchers used this information to develop an online tool that predicts someone's risk of death within the next five years. The study's strengths include its large sample size and the prospective nature of the study design. But there are some limitations. There may be some bias in the type of people who volunteered to take part. The death rate was lower than that of the average population in this age group, which may indicate that the participants were more interested in their health and so had he...
Source: NHS News Feed - June 4, 2015 Category: Consumer Health News Tags: Heart/lungs Cancer Lifestyle/exercise Medical practice Source Type: news

Editorial Increasing the power of public awareness campaigns
Barely a month seems to go by without a public awareness effort focused on a disorder of the nervous system. May 2015 alone saw American Stroke Month, UK Dementia Awareness Week (May 17–23), UK National Epilepsy Week (May 17–23), and World MS Day (May 27) among others. Raising public awareness and understanding is a crucial part of efforts to reduce the global burden of neurological disorders. But as the number and variety of campaigns has increased, from community-based education programmes to global initiatives, so too has our appreciation of the challenges of bringing about changes in behaviour that have a real impa...
Source: Lancet Neurology - June 8, 2015 Category: Neurology Authors: The Lancet Neurology Tags: Editorial Source Type: research

Half a handful of nuts a day 'reduces early death risk'
Conclusion This Dutch cohort of middle-aged to elderly adults generally found people were less likely to die in the following 10 years if they ate a small number of nuts a day compared with none. The study has strengths in its large sample size and that cause of death was followed up for the full cohort using valid medical codes. However, there are various points to bear in mind before we jump to the conclusion that nuts are the magic ingredient that will slash our risk of death. No clear trends It is difficult to draw any clear interpretations about how nut consumption may be associated with risk of death overall or fr...
Source: NHS News Feed - June 12, 2015 Category: Consumer Health News Tags: Food/diet Cancer Heart/lungs Diabetes Source Type: news

All-cause and disease-specific mortality among male, former elite athletes: an average 50-year follow-up
Conclusions Elite athletes have 5–6 years additional life expectancy when compared to men who were healthy as young adults. Lower mortality for cardiovascular disease was in part due to lower rates of smoking, as tobacco-related cancer mortality was especially low.
Source: British Journal of Sports Medicine - June 17, 2015 Category: Sports Medicine Authors: Kettunen, J. A., Kujala, U. M., Kaprio, J., Backmand, H., Peltonen, M., Eriksson, J. G., Sarna, S. Tags: Health education Original article Source Type: research