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Association between antiviral treatment and extrahepatic outcomes in patients with hepatitis C virus infection
Conclusions Antiviral treatment for HCV is associated with improved renal and circulatory outcomes, but unrelated to catastrophic autoimmune diseases.
Source: Gut - February 3, 2015 Category: Gastroenterology Authors: Hsu, Y.-C., Ho, H. J., Huang, Y.-T., Wang, H.-H., Wu, M.-S., Lin, J.-T., Wu, C.-Y. Tags: Hepatology Source Type: research

Could pharmacological curtailment of the RhoA/Rho-kinase pathway reverse the endothelial barrier dysfunction associated with Ebola virus infection?
Publication date: February 2015 Source:Antiviral Research, Volume 114 Author(s): Shahram Eisa-Beygi , Xiao-Yan Wen Activation of the RhoA/Rho-kinase (ROCK) pathway induces endothelial barrier dysfunction and increased vascular permeability, which is a hallmark of various life-threatening vascular pathologies. Therapeutic approaches aimed at inhibiting the RhoA/ROCK pathway have proven effective in the attenuation of vascular leakage observed in animal models of endotoxin-induced lung injury/sepsis, edema, autoimmune disorders, and stroke. These findings suggest that treatments targeting the ROCK pathway might be of benef...
Source: Antiviral Therapy - January 2, 2015 Category: Virology Source Type: research

Herpes Zoster and Dementia: A Nationwide Population-Based Cohort Study.
CONCLUSIONS: Herpes zoster was associated with an increased risk of dementia, independent of potential confounding factors. Antiviral treatment might be protective in preventing dementia in patients with herpes zoster. PMID: 29244265 [PubMed - as supplied by publisher]
Source: Journal of Clinical Psychiatry - December 16, 2017 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research