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Ambulatory blood pressure variability and risk of cardiovascular events, all-cause mortality, and progression of kidney disease
Conclusion: Greater ambulatory SBP variabilities were associated with increased risks for nonfatal cardiovascular diseases, all-cause mortality, and rapid kidney function decline in patients with CKD.
Source: Journal of Hypertension - August 13, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: BP variability Source Type: research

Blood pressure variability and microvascular dysfunction: the Maastricht Study
Conclusion: Greater systolic and diastolic BPV was associated with higher albuminuria, but not with CSVD features, flicker light-induced retinal arteriolar and venular dilation response, heat-induced skin hyperemia and plasma biomarkers of MVD. This suggests that the microvasculature of the kidneys is most vulnerable to the detrimental effects of greater BPV.
Source: Journal of Hypertension - July 30, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage - clinical aspects Source Type: research

Blood pressure variability and risk of stroke in chronic kidney disease
No abstract available
Source: Journal of Hypertension - March 6, 2020 Category: Cardiology Tags: EDITORIAL COMMENTARIES Source Type: research

Association of visit-to-visit variability in blood pressure and first stroke risk in hypertensive patients with chronic kidney disease
Conclusion: In hypertensive adults with mild-to-moderate CKD, visit-to-visit variability in BP was significantly associated with the risk of subsequent first stroke.
Source: Journal of Hypertension - March 6, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research

Prevalence of refractory hypertension in the United States from 1999 to 2014
Conclusions: We provided the first nationally representative estimate of refractory hypertension prevalence in US adults.
Source: Journal of Hypertension - August 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research

Difference in SBP between arms is a predictor of chronic kidney disease development in the general Korean population
Conclusion: Increased IASBPD is an independent predictor of incident CKD in the general population.
Source: Journal of Hypertension - March 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Kidney Source Type: research

Carotid intima–media thickness, but not chronic kidney disease independently associates with noncardiac arterial vascular events in South Africa
Aim: Although chronic kidney disease (CKD) as determined from estimated glomerular filtration rate (eGFR) is recommended for risk prediction by current hypertension guidelines, the equations to derive eGFR may not perform well in black Africans. We compared whether across the adult lifespan, eGFR or CKD are as closely associated with noncardiac arterial vascular events, as carotid intima–media thickness (IMT), in Africa. Methods: In 1152 black South Africans [480 with noncardiac arterial events (294 with critical lower limb ischemia, 186 with stroke) of which 37% were premature] and 672 age, sex and ethnicity-matche...
Source: Journal of Hypertension - March 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Kidney Source Type: research

BMI is associated with the development of chronic kidney diseases in hypertensive patients with normal renal function
Objective: We aimed to investigate the relationship of BMI and waist circumference with the development of chronic kidney disease (CKD). Methods: A total of 12 672 hypertensive patients with estimated glomerular filtration rate (eGFR) at least 60 ml/min per 1.73 m2 from the renal sub-study of the China Stroke Primary Prevention Trial (CSPPT) were included. The primary outcome was the development of CKD, defined as a decrease in eGFR of at least 30% and to a level of less than 60 ml/min per 1.73 m2 at the exit visit, or end-stage renal disease. A secondary outcome was rapid renal function decline, defined as ...
Source: Journal of Hypertension - September 21, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Obesity Source Type: research

Do patients actually do what we ask: patient fidelity and persistence to the Targets and Self-Management for the Control of Blood Pressure in Stroke and at Risk Groups blood pressure self-management intervention
Conclusion: Most patients randomized to self-management completed training; however, 36% of these had dropped out by 12 months. Self-monitoring was largely undertaken properly and accurately recorded. Fidelity with self-management was associated with lower achieved SBP. Successful implementation of self-management into daily practice requires careful training and should be accompanied by monitoring of fidelity.
Source: Journal of Hypertension - June 28, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Target home morning SBP be below 125 mmHg in type 2 diabetes patients
Background: It is not established to what extent self-monitoring of home BP be lowered in patients with type 2 diabetes. We tested the hypothesis that the appropriate home morning SBP cutoff value is 125 mmHg in our stratification of cardiovascular risk in type 2 diabetes. Method: Clinic and home BP monitoring were performed in 4308 individuals (1057 people with diabetes and 3251, nondiabetes), and we tested two cutoff values of home morning SBP (MSBP): 135 and 125 mmHg. Multivariable Cox regression analyses adjusting for age, sex, body mass index, history of cardiovascular events, presence of chronic kidney disea...
Source: Journal of Hypertension - May 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: BP measurement Source Type: research

Visit-to-visit blood pressure variability is a risk factor for all-cause mortality and cardiovascular disease: a systematic review and meta-analysis
Conclusion: In summary, among the wide heterogenetic population, modest associations between VVV of SBP and all-cause mortality, CVD incidence, CVD mortality, CHD incidence, and stroke incidence were found. Findings of the current study suggested that standardized approaches of monitoring VVV in the high-risk population, including patients with cardiac infarction, diabetes, stroke, and patients with chronic kidney disease or in dialysis, are necessary in designing a prospective clinical study on the association of VVV and patients’ prognosis.
Source: Journal of Hypertension - December 1, 2016 Category: Cardiology Tags: Reviews Source Type: research

Renal function and attributable risk of death and cardiovascular hospitalization in patients with cardiovascular risk factors from a registry-based cohort: the Estudio Cardiovascular Valencia-risk study
Conclusion: In a large general practice cohort of patients with cardiovascular disease risk factors, decreasing eGFR levels were associated with additional attributed risk of mortality and cardiovascular disease. Our findings underscore that intensified efforts are needed to reduce the cardiovascular disease burden associated to chronic kidney disease.
Source: Journal of Hypertension - September 30, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Kidney Source Type: research

Visit-to-visit variability of blood pressure and death, end-stage renal disease, and cardiovascular events in patients with chronic kidney disease
Conclusion: Higher VVV of BP is independently associated with higher rates of death and hemorrhagic stroke in patients with moderate to advanced CKD not yet on dialysis.
Source: Journal of Hypertension - December 23, 2015 Category: Cardiology Tags: ORIGINAL PAPERS: BP measurement Source Type: research

Development of new atherosclerotic plaque in hypertensive patients: an observational registry study from the Campania-Salute network
Background and purpose: Carotid atherosclerotic plaques (CAPs) can develop despite appropriate antihypertensive therapy. In this observational study, we assessed characteristics associated with risk of incident CAP in a large hypertensive registry. Methods: We evaluated 2143 hypertensive patients without evidence of CAP. Incident CAP was censored at the time of the first ultrasound control in which CAP was detected. CAP was defined according to European Society of Hypertension/European Society of Cardiology guidelines. Results: At a median follow-up period of 56.6 months, about one-third of patients (32%; N = 688) exhi...
Source: Journal of Hypertension - November 12, 2015 Category: Cardiology Tags: ORIGINAL PAPERS: Blood vessels Source Type: research

Sex differences in cardiovascular outcomes in patients with incident hypertension
Conclusion: In this cohort with incident hypertension, women were more likely to develop CKD and less likely to develop other cardiovascular outcomes compared with men. Future studies should investigate the potential reasons for these sex differences.
Source: Journal of Hypertension - January 11, 2013 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research