Blood pressure variability and microvascular dysfunction: the Maastricht Study

Conclusion: Greater systolic and diastolic BPV was associated with higher albuminuria, but not with CSVD features, flicker light-induced retinal arteriolar and venular dilation response, heat-induced skin hyperemia and plasma biomarkers of MVD. This suggests that the microvasculature of the kidneys is most vulnerable to the detrimental effects of greater BPV.
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage - clinical aspects Source Type: research

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Abstract The brain endocannabinoid system has been shown to play a role in many physiological processes, including mood, learning and memory. It is also involved in the pathogenesis of anxiety, depression, mood disorders, as well as neurodegenerative disorders, although the exact mechanisms by which cannabinoid receptors interfere in these disorders are not well established. The aim of the present study was to evaluate the effects of cannabinoid ligands HU‑210 (CB1 receptor agonist) and SR 141716A (CB1 receptor antagonist) on learning and memory processes of rats with depressive - like state, induced by bilatera...
Source: Acta Neurobiologiae Experimentalis - Category: Neurology Authors: Tags: Acta Neurobiol Exp (Wars) Source Type: research
This study aims to evaluate potential anxiolytic effects of aerobic exercise in streptozotocin (STZ)‑induced diabetes. Male Wistar albino rats (n=40) were randomly divided into four groups of control, exercise, diabetes, and diabetes + exercise. Diabetes was induced with a single i.p. injection of STZ. The incremental load test was applied to exercise groups to determine maximal exercise capacity. Rats exercised on a treadmill at 70% of their maximal capacity for 45 min, five days per week for 12 weeks. On the day after the last exercise session the open field test and elevated plus maze test were carried out. Diabetes c...
Source: Acta Neurobiologiae Experimentalis - Category: Neurology Authors: Tags: Acta Neurobiol Exp (Wars) Source Type: research
CONCLUSION: The well-established CPU concept could additionally benefit from a superordinate quality control. Adequate quality benchmarking appears to be fundamental for gap analyses and for the establishment of a separate remuneration structure. In this respect the German Society for Cardiology as the certifying institution is required to establish an appropriate mechanism within the framework of regular updates of criteria. PMID: 32990815 [PubMed - as supplied by publisher]
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
CONCLUSION: We found that 15.6% of the patients with PH-LHD under pharmacological or nonpharmacological treatment had PAWP ≤15 mm Hg. These results suggest that the diagnostic criterion of PAWP and the characteristics for this group of patients should be further investigated. PMID: 32990814 [PubMed - as supplied by publisher]
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
INTRODUCTION: Suicide attempt may be common among adolescents. Less is known about this in the Pacific Island country, Tonga. Therefore, this analysis estimated the frequency of suicide attempts as well as its associated factors among adolescents in Tonga....
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Background and Aims: Poisoning is most common method of committing suicide in India. OBJECTIVEs of this study to assess prevalence of suicidal poisoning among all poisoning cases, its socio-demographic profile and its reasons in all admitted cases ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Publication date: October 2020Source: IJC Heart &Vasculature, Volume 30Author(s): Waqas Ullah, Donald Haas, Talal Almas, Aws- Al-Mukhtar, Asad Inayat
Source: IJC Heart and Vasculature - Category: Cardiology Source Type: research
Although CKD patients and physicians may hesitate to embrace TAVR given the perceived risks of worsening renal function, data suggest that may not be the case for most.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Cardiology News Source Type: news
CONCLUSION: These results indicate that an 8-week multimodal day-care rehabilitation programme can be tolerable, reduce psychiatric symptoms, and improve health-related quality of life for people with HD. A higher sense of coherence seems to promote attendance rates. Further larger studies, including the impact of cognition and disease progression on the treatment effect, are warranted. PMID: 32989469 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - Category: Rehabilitation Tags: J Rehabil Med Source Type: research
This article describes the immediate challenges and opportunities that can launch nationwide reform in systems of care for individuals in psychiatric crisis. Five action recommendations describe clear, feasible next steps that can be taken to move these systems forward and meaningfully improve access and quality of care for people in crisis. The recommendations include a central coordinating role for Congress, an increase in federal authorization and appropriation of funds, enactment of a 5% Mental Health Block Grant set-aside, expanded funding for research and evaluation, and the pursuit of additional payment mechanisms b...
Source: Psychiatric Services - Category: Psychiatry Tags: Psychiatr Serv Source Type: research
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