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Specialty: Neuroscience
Condition: Anxiety
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Total 108 results found since Jan 2013.
Targeting the neurological comorbidities of multiple sclerosis: the beneficial effects of VIP and PACAP neuropeptides
J Integr Neurosci. 2022 Jan 28;21(1):33. doi: 10.31083/j.jin2101033.ABSTRACTVasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are two widely expressed neuropeptides with important immunomodulatory and neuroprotective properties in the central nervous system (CNS). Both VIP and PACAP have been implicated in several neurological diseases and have shown favourable effects in different animal models of multiple sclerosis (MS). MS is a chronic inflammatory and neurodegenerative disease of the CNS affecting over 2.5 million people worldwide. The disease is characterised by extensi...
Source: Journal of Integrative Neuroscience - February 15, 2022 Category: Neuroscience Authors: Margo I Jansen Sarah Thomas Broome Alessandro Castorina Source Type: research
Progranulin promotes hippocampal neurogenesis and alleviates anxiety-like behavior and cognitive impairment in adult mice subjected to cerebral ischemia
CONCLUSIONS: Progranulin alleviates ischemia-induced anxiety-like behavior and spatial learning and memory impairment in mice, probably via stimulation of hippocampal neurogenesis mediated by activation of MAPK/ERK and PI3K/Akt pathways. PGRN might be a promising candidate for coping with ischemic stroke-induced mood and cognitive impairment in clinic.PMID:35146924 | DOI:10.1111/cns.13810
Source: CNS Neuroscience and Therapeutics - February 11, 2022 Category: Neuroscience Authors: Siqi Sun Jinlong Zhou Zhongqi Li Yuzi Wu Hao Wang Qi Zheng Frank Adu-Nti Juan Fan Yingfang Tian Source Type: research
