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Condition: Anxiety
Drug: Nicotine
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Total 966 results found since Jan 2013.
Withdrawal from repeated nicotine vapor exposure increases somatic signs of physical dependence, anxiety-like behavior, and brain reward thresholds in adult male rats
In this study we assessed markers of withdrawal following 14 days of nicotine vapor exposure. For Experiment 1, 21 adult male rats were exposed to air or nicotine vapor for 14 consecutive days. Following exposure on day 14, rats were injected with the nicotinic receptor antagonist mecamylamine (3.0 mg/mL) and assessed for somatic withdrawal signs and anxiety-like behavior in the elevated plus maze. For Experiment 2, 12 adult male rats were tested for intracranial self-stimulation (ICSS) immediately following exposure to vehicle vapor (50%/50%, vegetable glycerin/propylene glycol) or nicotine vapor, for 14 consecutive days....
Source: Neuropharmacology - August 23, 2023 Category: Drugs & Pharmacology Authors: Michelle Mart ínez Veronika E Espinoza Valeria Garcia Kevin P Uribe Kenichiro Negishi Igor L Estevao Luis M Carcoba Laura E O'Dell Arshad M Khan Ian A Mendez Source Type: research
The influence of pain-related comorbidities on pain intensity and pain-related psychological distress in patients presenting with musculoskeletal pain
CONCLUSIONS: Depression was associated with greater pain intensity. No comorbidities were able to account for the extent of pain-related psychological distress.PMID:37611373 | DOI:10.1016/j.bjpt.2023.100532
Source: Health Physics - August 23, 2023 Category: Physics Authors: Steven L Spoonemore Ryan C McConnell William E Owen Jodi L Young Derek J Clewley Daniel I Rhon Source Type: research
Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health."
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Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis?
https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/
Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The effect of nicotine on antidepressant and anxiolytic responses induced by citalopram and citicoline in mice
In conclusion, these findings suggest that interactions between nicotine and citalopram or citicoline occur upon induction of anxiolytic and antidepressant responses in mice.PMID:37493535 | DOI:10.55782/ane-2023-017
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Fatemeh Khakpai Mohammad-Reza Zarrindast Source Type: research
