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Total 447 results found since Jan 2013.

Clinical Benefit of Warfarin in Dialysis Patients With Atrial Fibrillation
Patients with atrial fibrillation (AF) and end-stage chronic kidney disease (CKD) receiving dialysis are at higher risk of stroke (1). Warfarin has been shown to reduce the frequency of strokes by 64.0% in patients with AF; however, its use in dialysis patients has not received consensus owing to the lack of randomized controlled trial data and associated increased bleeding risk.
Source: Journal of the American College of Cardiology - September 7, 2015 Category: Cardiology Source Type: research

Beyond the Aortic Root: Staged Open and Endovascular Repair of Arch and Descending Aorta in Patients with Connective Tissue Disorders
Conclusions Most patients with CTDs who require operations beyond the aortic root have aortic dissection and require multiple reinterventions. Staged repair strategies, including open repair in combination with TEVAR, are feasible, and benefits outweigh risks. These patients require lifelong imaging surveillance.
Source: The Annals of Thoracic Surgery - November 4, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Beyond the Aortic Root: Staged Open and Endovascular Repair of Arch and Descending Aorta in Patients with Connective Tissue Disorders.
CONCLUSIONS: Most patients with CTDs who require operations beyond the aortic root have aortic dissection and require multiple reinterventions. Staged repair strategies, including open repair in combination with TEVAR, are feasible, and benefits outweigh risks. These patients require lifelong imaging surveillance. PMID: 26545624 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - November 3, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Roselli EE, Idrees JJ, Lowry AM, Masabni K, Soltesz EG, Johnston DR, Kalahasti V, Blackstone EH, Sabik JF, Lytle BW, Svensson LG Tags: Ann Thorac Surg Source Type: research

Clinical Outcomes of Drug-Eluting Stents vs. Bare-Metal Stents in Acute Myocardial Infarction Patients Under Dialysis　- A Nationwide Cohort Study.
CONCLUSIONS: Among AMI patients on dialysis undergoing percutaneous coronary interventions, DES implantation significantly reduced the risk of recurrent MI, CV death and all-cause mortality compared with BMS implantation. PMID: 26581755 [PubMed - as supplied by publisher]
Source: Circulation Journal - November 19, 2015 Category: Cardiology Authors: Chen DY, Mao CT, Tsai ML, Hsieh MJ, Lin YS, Cherng WJ, Wen MS, Wang CH, Hsieh IC, Hung MJ, Chen CC, Chen TH Tags: Circ J Source Type: research

The Effect of Cardiopulmonary Bypass on Dabigatran Levels
DABIGATRAN IS a novel anticoagulant that is licensed for use for the prevention of stroke in the presence of atrial fibrillation. Its use has expanded rapidly in New Zealand, primarily due to there being no requirement for routine monitoring of its effect, as there is for warfarin. There are case reports in the literature describing management of patients coming for urgent cardiac surgery, which revolve mainly around the use of dialysis and massive transfusion of clotting factors to manage the bleeding associated with surgery.
Source: Journal of Cardiothoracic and Vascular Anesthesia - December 31, 2015 Category: Anesthesiology Authors: Kelly Byrne Tags: CASE REPORT Source Type: research

Pulsatile-flow mechanical circulatory support (MCS) as a bridge to transplantation or recovery. Single-centre experience with the POLCAS system in 2014.
CONCLUSIONS: The POLCAS heart assist system is an effective method of treatment as a bridge to transplantation or recovery in patients with end-stage heart failure. Early survival after the treatment remains at a satisfactory level. The main problem is the large number of complications related to the therapy. PMID: 26702278 [PubMed]
Source: Polish Journal of Cardio-Thoracic Surgery - January 20, 2016 Category: Cardiovascular & Thoracic Surgery Tags: Kardiochir Torakochirurgia Pol Source Type: research

The outcomes of transcatheter aortic valve replacement in a cohort of patients with end‐stage renal disease
ConclusionsPatients with ESRD who undergo TAVR are at high risk for mortality and complications. TAVR outcomes are comparable to but not substantially better than those with SAVR. Transfemoral TAVR seems to be at least as safe and effective as the current standard SAVR in patients undergoing aortic valve replacement. © 2016 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - March 4, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Molly Szerlip, Rebeca J. Kim, Tokunbo Adeniyi, Vinod Thourani, Vasilis Babaliaros, Joseph Bavaria, Howard C. Herrmann, Saif Anwaruddin, Raj Makkar, Tarun Chakravarty, Joshua Rovin, Don Creighton, D. Craig Miller, Kim Baio, Elizabeth Walsh, Jasmina Katinic Tags: Valvular and Structural Heart Diseases Source Type: research

Is emergency and salvage coronary artery bypass grafting justified? The Nordic Emergency/Salvage coronary artery bypass grafting study ADULT CARDIAC
CONCLUSIONS Early mortality in patients undergoing emergent and salvage CABG is substantial, especially in salvage patients. Long-term survival is acceptable in both emergent and salvage patients. Life-saving emergency and salvage CABG is justified in most patients but salvage patients have dismal prognosis if cardiac massage is needed during sternotomy.
Source: European Journal of Cardio-Thoracic Surgery - April 28, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Axelsson, T. A., Mennander, A., Malmberg, M., Gunn, J., Jeppsson, A., Gudbjartsson, T. Tags: Electrophysiology - arrhythmias, Molecular biology ADULT CARDIAC Source Type: research

Reexploration for Bleeding and Its Association With Mortality After Cardiac Surgery
Conclusions Excessive bleeding leading to reexploration is associated with a twofold increased early postoperative mortality rate. Reexploration for bleeding is also associated with mortality beyond 90 days after operation.
Source: The Annals of Thoracic Surgery - June 27, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Post‐operative serious adverse events in a mixed surgical population – a retrospective register study
ConclusionWe found a risk of one or more events in the composite outcome within 342 days after inclusion of the last patients of 8.3% (7.8–9.0). The results are applicable in estimations of adequate sample sizes in future clinical trials investigating effects of interventions on SAEs.
Source: Acta Anaesthesiologica Scandinavica - July 15, 2016 Category: Anesthesiology Authors: M. S. Hansen, E. E. Petersen, J. B. Dahl, J. Wetterslev Tags: Original Article Source Type: research

Use of Contraindicated Antiplatelet Medications in the Setting of Percutaneous Coronary Intervention: Insights From the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program Original Articles
Conclusions— In this national cohort, 18% of patients undergoing PCI had contraindications to common antiplatelet medications. Approximately 6% of those patients received a contraindicated medication with attendant bleeding risk, although this did not translate into significantly higher risk of 30-day mortality. Continued efforts to reduce contraindicated medication use may help avoid periprocedural complications.
Source: Circulation: Cardiovascular Quality and Outcomes - July 18, 2016 Category: Cardiology Authors: Barnes, G. D., Stanislawski, M. A., Liu, W., Baron, A. E., Armstrong, E. J., Ho, P. M., Klein, A., Maddox, T. M., Nallamothu, B. K., Rumsfeld, J. S., Tsai, T. T., Bradley, S. M. Tags: Platelets, Anticoagulants, Percutaneous Coronary Intervention, Stent, Quality and Outcomes Original Articles Source Type: research

Post ‐operative serious adverse events in a mixed surgical population – a retrospective register study
ConclusionWe found a risk of one or more events in the composite outcome within 342 days after inclusion of the last patients of 8.3% (7.8–9.0). The results are applicable in estimations of adequate sample sizes in future clinical trials investigating effects of interventions on SAEs.
Source: Acta Anaesthesiologica Scandinavica - July 13, 2016 Category: Anesthesiology Authors: M. S. Hansen, E. E. Petersen, J. B. Dahl, J. Wetterslev Tags: Original Article Source Type: research

The Effect of Cardiopulmonary Bypass on Dabigatran Levels
DABIGATRAN IS a novel anticoagulant that is licensed for use for the prevention of stroke in the presence of atrial fibrillation. Its use has expanded rapidly in New Zealand, primarily due to there being no requirement for routine monitoring of its effect, as there is for warfarin. There are case reports in the literature describing management of patients coming for urgent cardiac surgery, which revolve mainly around the use of dialysis and massive transfusion of clotting factors to manage the bleeding associated with surgery.
Source: Journal of Cardiothoracic and Vascular Anesthesia - December 30, 2015 Category: Anesthesiology Authors: Kelly Byrne Tags: CASE REPORT Source Type: research

Five ‐year mortality outcomes in patients with chronic kidney disease undergoing percutaneous coronary intervention
ConclusionAmong patients undergoing PCI, lower GFR is associated with decreased long‐term survival. © 2016 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - August 12, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Agam D. Patel, Mohammed Ibrahim, Rajesh V. Swaminathan, Irfan U. Minhas, Luke K. Kim, Prashanth Venkatesh, Dmitriy N. Feldman, Robert M. Minutello, Geoffrey W. Bergman, S. Chiu Wong, Harsimran S. Singh Tags: Coronary Artery Disease Source Type: research

Is moderate hypothermic circulatory arrest with selective antegrade cerebral perfusion superior to deep hypothermic circulatory arrest in elective aortic arch surgery?
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether moderate hypothermia circulatory arrest with selective antegrade cerebral perfusion (SACP) is more beneficial than deep hypothermic circulatory arrest in elective aortic arch surgery. Altogether, 1028 papers were found using the reported search, of which 6 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. There were four retrospective obser...
Source: Interactive CardioVascular and Thoracic Surgery - August 21, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Poon, S. S., Estrera, A., Oo, A., Field, M. Tags: Extracorporeal circulation Adult Cardiac Source Type: research