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Sex Difference of Radiation Response in Occupational and Accidental Exposure
Conclusion and Outlook This review summarizes the data from major human studies on the health risks of radiation exposure and shows that sex can potentially influence the prolonged response to radiation exposure (Figure 1 and Tables 1, 2). These data suggest that long-term radiosensitivity in females is higher than that in males who receive a comparable dose of radiation. Our analysis of the literature agrees with the conclusions of the recent report on the Biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences (NAS), United States (National Research Council, 2006). The B...
Source: Frontiers in Genetics - May 2, 2019 Category: Genetics & Stem Cells Source Type: research

Minimally Invasive Mitral Valve Repair Through Right Minithoracotomy 　- 11-Year Single Institute Experience.
CONCLUSIONS: MIMVR can be performed safely with low levels of mortality and morbidity, and provides sufficient repair durability. A learning curve exists in terms of repair durability, especially for anterior mitral leaflet repair. PMID: 29657253 [PubMed - as supplied by publisher]
Source: Circulation Journal - April 13, 2018 Category: Cardiology Authors: Sakaguchi T, Totsugawa T, Kuinose M, Tamura K, Hiraoka A, Chikazawa G, Yoshitaka H Tags: Circ J Source Type: research

Is Aortic Valve Repair Reproducible? Analysis of the Learning Curve for Aortic Valve Repair
Conclusions Procedural safety and efficiency improves with experience whereas efficacy is consistent over time. AV repair is reproducible and appears to have a learning curve of approximately 40-60 cases. Teaser Aortic valve repair, while effective, is performed in a limited number of centres. We examined the learning curve in two centres with programs in AV repair for safety, efficiency, and efficacy endpoints. Early mortality was ≤1% in both cohorts. Frequency of safety endpoints was reduced in both cohorts. Procedural safety and efficiency improved with experience whereas efficacy was consistent over time. AV repair i...
Source: Canadian Journal of Cardiology - June 1, 2015 Category: Cardiology Source Type: research