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Condition: Thrombocytopenia
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Total 366 results found since Jan 2013.
Hemorrhagic stroke associated to COVID-19 infection in Mexico General Hospital
CONCLUSIONES: la HC se asocia a la infección por SARS-CoV-2 con mal pronóstico cuando se presenta. Los equipos de neurocirugía deben estar preparados para el tratamiento oportuno de estos pacientes.INTRODUCTION: In the current COVID-19 pandemic, there is a growing body of evidence that has identified the neurotropism of the SARS-CoV-2 virus and its neurological complications, including cerebrovascular disease, focusing mainly in ischemic and scarcely about hemorrhagic stroke (HS).OBJECTIVE: The objective of the study was to describe clinical, radiological, laboratory tests, and prognostic characteristics of patients wit...
Source: Cirugia y Cirujanos - August 5, 2021 Category: Surgery Authors: Gustavo Parra-Romero Ariatne Mar- Álvarez Jos é L Navarro-Olvera Aldo F Hern ández-Valencia Gustavo Aguado-Carrillo Jos é D Carrillo-Ruiz Source Type: research
Hematologic Emergencies in the Postoperative Neurointensive Care Unit Setting: Illustrative Case Series and Differential Diagnosis
Disseminated intravascular coagulation (DIC), a consumptive coagulopathy, occurs as a complication of various conditions. The coagulation pathway is activated leading to formation of fibrin clots that are then released into the circulation. This results in ischemia and subsequent organ failure along with simultaneous consumption of platelets and coagulation factors leading to hemorrhage.1 Diagnostic criteria for DIC include thrombocytopenia, prolonged prothrombin time, reduced fibrinogen levels, and increase in fibrinogen degradation products.
Source: Journal of Stroke and Cerebrovascular Diseases - August 3, 2021 Category: Neurology Authors: Rana Hanna Al Shaikh, Oluwaseun O. Akinduro, Tasneem F. Hasan, Seung Jin Lee, Ernesto Ayala, Alfredo E. Quinones-Hinojosa, Kristin A. Cushenbery, Julie E. Hammack, Jang Won Yoon, Dennis W. Dickson, William D. Freeman Source Type: research
Complement dysregulation is associated with severe COVID-19 illness
Haematologica. 2021 Jul 22. doi: 10.3324/haematol.2021.279155. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2) may manifest as thrombosis, stroke, renal failure, myocardial infarction, and thrombocytopenia, reminiscent of other complement-mediated diseases. Multiple clinical and preclinical studies have implicated complement in the pathogenesis of COVID-19 illness. We previously found that the SARS-CoV-2 spike protein activates the alternative pathway of complement (APC) in vitro through interfering with the function of complement factor H, a key negative regulator of APC. Here, w...
Source: Haematologica - July 22, 2021 Category: Hematology Authors: Jia Yu Gloria F Gerber Hang Chen Xuan Yuan Shruti Chaturvedi Evan M Braunstein Robert A Brodsky Source Type: research
