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Risk factors for severe bleeding events during warfarin treatment: the influence of sex, age, comorbidity and co-medication
ConclusionMost of the well-established risk factors were found to be significantly associated with bleeding events in our study. We additionally found that women had a lower incidence of bleeding. Potential biases are selection effects, residual confounding and unmeasured frailty.
Source: European Journal of Clinical Pharmacology - March 27, 2020 Category: Drugs & Pharmacology Source Type: research

Outcome After Endovascular Repair of Ruptured Descending Thoracic Aortic Aneurysm: A National Multicentre Study.
CONCLUSIONS: This nationwide multicentre study of patients with rDTAA undergoing TEVAR showed acceptable short- but poor long-term survival. Adequate proximal and distal aortic sealing zones are important for technical success. High risk patients and post-operative complications need to be further addressed in an effort to improve outcome. PMID: 30910493 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - March 21, 2019 Category: Surgery Authors: Sari H, Thomas L, Rebecka H, Anders W, Kevin M, Timothy R, Mårten F, Claes F, Björn S, Artai P, Håkan R, Tina H, Shazhad K, Jonas H, Carl-Magnus W Tags: Eur J Vasc Endovasc Surg Source Type: research

Non-cardiac comorbidities and mortality in patients with heart failure with reduced vs. preserved ejection fraction: a study using the Swedish Heart Failure Registry
ConclusionsNon-cardiac comorbidities contribute significantly but differently to mortality, both in HFrEF and HFpEF. No significant variation was found in the impact over the 12-year study period. These results emphasize the importance of including the management of comorbidities as a part of a standardized heart failure care in both HF phenotypes.
Source: Clinical Research in Cardiology - February 20, 2019 Category: Cardiology Source Type: research

Amputation Rates, Mortality, and Pre-operative Comorbidities in Patients Revascularised for Intermittent Claudication or Critical Limb Ischaemia: A Population Based Study.
CONCLUSION: The risk of amputation is particularly high during the first 6 months following revascularisation for CLI. IC patients have a benign course in terms of limb loss. Mortality in both IC and CLI patients is substantial. Revascularised CLI patients have different comorbidities from IC patients. PMID: 28797662 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - August 7, 2017 Category: Surgery Authors: Baubeta Fridh E, Andersson M, Thuresson M, Sigvant B, Kragsterman B, Johansson S, Hasvold P, Falkenberg M, Nordanstig J Tags: Eur J Vasc Endovasc Surg Source Type: research