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Condition: Restrictive Cardiomyopathy

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Total 16 results found since Jan 2013.

Neurologic Complications After Pediatric Heart Transplant: A Single-Center Experience
CONCLUSIONS: Neurologic complications may lead to serious mortality and morbidity in pediatric heart transplant patients. Seizures, posterior reversible encephalopathy syndrome, stroke, peripheral neuropathy, transient ischemic attack, and cerebral infections are the most common neurologic complications, which are seen in the perioperative period in particular. Careful follow-up of pediatric heart transplant patients, with detection and early treatment of neurologic findings, will contribute to lower rates of sequelae. To our knowledge, this is the largest study to show a detailed experience of neurologic complications in ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 2, 2021 Category: Transplant Surgery Authors: Ali Orgun Ilkay Erdogan Birg ül Varan Taner Sezer N K ürsad Tokel Murat Özkan Atilla Sezgin Source Type: research

Transthyretin cardiac amyloidosis.
Authors: Eicher JC, Audia S, Damy T Abstract Transthyretin (TTR) cardiac amyloidosis results from the dissociation of the tetrameric, liver-synthetized transport protein, either because of a mutation (hereditary CA), or spontaneously due to ageing (wild type CA). Monomers self-associate into amyloid fibrils within the myocardium, causing heart failure, arrhythmias and conduction defects. This overlooked disease must be recognized in case of unexplained increased thickness of the myocardium, particularly in subjects of African descent, in patients with heart failure and preserved ejection fraction, and in those with...
Source: Revue de Medecine Interne - August 23, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

Endovascular treatment of stroke in children under 2 years with heart failure and ventricular assist device.
CONCLUSION: As a result of the difficulty in performing arterial puncture, the small vessel calibre and the limitation in the use of iodated contrast, there are certain limitations to endovascular treatment of strokes in children that can lead to complications. A multidisciplinary approach to managing such cases would be helpful. PMID: 31072251 [PubMed - as supplied by publisher]
Source: Interventional Neuroradiology - May 12, 2019 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Outcomes of Berlin Heart EXCOR ® pediatric ventricular assist device support in patients with restrictive and hypertrophic cardiomyopathy
This study reviews the North American experience with Berlin Heart EXCOR® ventricular assist device implants in children with such physiology. The Berlin Heart clinical database was reviewed. Patients with primary diastolic dysfunction are included in this study. Twenty pediatric patients with restrictive cardiomyopathy (n = 13), hypertrophic cardiomyopathy (n = 3), or congenital heart disease with restrictive physiology (n = 4) who were supported with EXCOR® were identified. Of these, nine (45%) were successfully bridged to transplant, one (5%) weaned from support, and 10 (50%) died after support was withdrawn. Of...
Source: Pediatric Transplantation - September 1, 2017 Category: Transplant Surgery Authors: Jennifer A. Su, Jondavid Menteer Tags: ORIGINAL ARTICLE Source Type: research

Myocardial Upregulation of Cathepsin D by Ischemic Heart Disease Promotes Autophagic Flux and Protects Against Cardiac Remodeling and Heart Failure Original Articles
Conclusions Myocardial CTSD upregulation induced by myocardial infarction protects against cardiac remodeling and malfunction, which is at least in part through promoting myocardial autophagic flux.
Source: Circulation: Heart Failure - July 10, 2017 Category: Cardiology Authors: Wu, P., Yuan, X., Li, F., Zhang, J., Zhu, W., Wei, M., Li, J., Wang, X. Tags: Basic Science Research, Myocardial Biology, Chronic Ischemic Heart Disease, Heart Failure, Myocardial Infarction Original Articles Source Type: research

Acute Pediatric Ischemic Stroke Management: a window for opportunity? (P4.175)
Conclusions:Pediatric stroke is a rare condition, with one of the most common causes being congenital cardiac disease. Unfortunately, we lack evidence-based guidelines to guide its management. Based upon pathophysiology, we believe children’s significant collateral circulation and outstanding plasticity may broaden the temporal window for intervention in acute stroke.Disclosure: Dr. Pace has nothing to disclose. Dr. Dorn has nothing to disclose. Dr. Kulhari has nothing to disclose. Dr. Kandregula has nothing to disclose. Dr. Bozorgi has nothing to disclose. Dr. Alrajeh has nothing to disclose. Dr. Manjila has nothing...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Pace, J., Dorn, E., Kulhari, A., Kandregula, K., Bozorgi, A., Alrajeh, M., Manjila, S., Ramos-Estebanez, C. Tags: Child Neurology II Source Type: research

'Real-world management and outcomes of patients with paroxysmal vs. non-paroxysmal atrial fibrillation in Europe: the EURObservational Research Programme-Atrial Fibrillation (EORP-AF) General Pilot Registry
Conclusion In this ‘real-world’ contemporary observational registry, patients with non-paroxysmal AF had a worse outcome, in terms of all-cause mortality, which was related to a more severe clinical profile. The risk of stroke at 1 year was relatively low, perhaps reflecting the high rates of anticoagulation use in this cohort.
Source: Europace - May 24, 2016 Category: Cardiology Authors: Boriani, G., Laroche, C., Diemberger, I., Fantecchi, E., Popescu, M. I., Rasmussen, L. H., Dan, G.-A., Kalarus, Z., Tavazzi, L., Maggioni, A. P., Lip, G. Y. H. Tags: Atrial fibrillation Source Type: research

Pericardiectomy: prompt surgical management of constrictive pericarditis.
CONCLUSION: Radical pericardiectomy is a demonstrably useful procedure for correction of hemodynamic abnormalities and improvement of overall heart function in symptomatic patients with constrictive pericarditis. PMID: 25586283 [PubMed - in process]
Source: The Heart Surgery Forum - December 1, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Inamdar KY, Aikebaier M, Lijunhong, Abudunaibi, Mulati A Tags: Heart Surg Forum Source Type: research

The use of a Berlin Heart EXCOR LVAD in a child receiving chemotherapy for Castleman's disease
We present the unique case of a pediatric patient who received chemotherapy for a diagnosis of CD, while mechanically supported with a Berlin EXCOR LVAD secondary to restrictive cardiomyopathy. A four‐yr‐old previously healthy male with restrictive cardiomyopathy required MCS after cardiac arrest but was diagnosed with multicentric CD, a non‐malignant lymphoproliferative disorder fueled by excessive IL‐6 production. Treatment with IL‐6 blockade (tocilizumab) every two wk and methylprednisolone had no effect on his lymph nodes or cardiac function while on temporary RotaFlow. A Berlin LVAD was placed for treatment...
Source: Pediatric Transplantation - December 1, 2014 Category: Transplant Surgery Authors: Tamara O. Thomas, Shanmuganathan Chandrakasan, Maureen O'Brien, John L. Jefferies, Thomas D. Ryan, Ivan Wilmot, Michael L. Baker, Peace C. Madueme, David Morales, Angela Lorts Tags: Case Report Source Type: research

Cardiomyopathy in neurological disorders
Abstract: According to the American Heart Association, cardiomyopathies are classified as primary (solely or predominantly confined to heart muscle), secondary (those showing pathological myocardial involvement as part of a neuromuscular disorder) and those in which cardiomyopathy is the first/predominant manifestation of a neuromuscular disorder. Cardiomyopathies may be further classified as hypertrophic cardiomyopathy, dilated cardiomyopathy, restrictive cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, or unclassified cardiomyopathy (noncompaction, Takotsubo-cardiomyopathy). This review focuses on seconda...
Source: Cardiovascular Pathology - February 25, 2013 Category: Cardiology Authors: Josef Finsterer, Claudia Stöllberger, Karim Wahbi Tags: Original Articles Source Type: research