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The brighter (and evolutionarily older) face of the metabolic syndrome: evidence from Trypanosoma Cruzi infection in CD‐1 mice
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Source: Diabetes/Metabolism Research and Reviews - January 1, 2015 Category: Endocrinology Authors: Wunnie Brima, Daniel J. Eden, Syed Faizan Mehdi, Michelle Bravo, Mohammad M. Wiese, Joanna Stein, Vanessa Almonte, Dazhi Zhao, Irwin Kurland, Jeffrey E. Pessin, Tomas Zima, Herbert B. Tanowitz, Louis M. Weiss, Jesse Roth, Fnu Nagajyothi Tags: Research Article Source Type: research

A Diet Rich in Medium-chain Fatty Acids Improves Systolic Function and Alters the Lipidomic Profile in Patients with Type 2 Diabetes: a Pilot Study.
CONCLUSIONS: Although a diet high in MCFAs does not change cardiac steatosis, our findings suggest that the MCFA-rich diet alters the plasma lipidome and may benefit or at least not harm cardiac function and fasting insulin levels in humans with type 2 diabetes. Larger, long-term studies are needed to further evaluate these effects in less controlled settings. PMID: 26652763 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - December 10, 2015 Category: Endocrinology Authors: Airhart S, Cade WT, Jiang H, Coggan AR, Racette SB, Korenblat K, Spearie CA, Waller S, O'Connor R, Bashir A, Ory DS, Schaffer JE, Novak E, Farmer M, Waggoner AD, Dávila-Román VG, Javidan-Nejad C, Peterson LR Tags: J Clin Endocrinol Metab Source Type: research

Endocrine manifestations and new developments in mitochondrial disease
Endocr Rev. 2021 Oct 13:bnab036. doi: 10.1210/endrev/bnab036. Online ahead of print.ABSTRACTMitochondrial diseases are a group of common inherited diseases causing disruption of oxidative phosphorylation. Some patients with mitochondrial disease have endocrine manifestations, with diabetes being predominant but also include hypogonadism, hypoadrenalism and hypoparathyroidism. There have been major developments in mitochondrial disease over the last decade that have major implications for all patients. The collection of large cohorts of patients has better defined the phenotype of mitochondrial diseases and the majority of ...
Source: Endocrine Reviews - October 13, 2021 Category: Endocrinology Authors: Yi Shiau Ng Albert Zishen Lim Grigorios Panagiotou Doug M Turnbull Mark Walker Source Type: research

Impact of diabetes mellitus on the outcomes of subjects with hypertrophic cardiomyopathy: a nationwide cohort study
Hypertrophic cardiomyopathy (HCM) is a relatively common genetic cardiomyopathy caused by sarcomeric gene mutations with an assumed prevalence of 1 in 200 persons,[1] and is characterized by left ventricular hypertrophy unexplained by other secondary causes. The clinical course of HCM is complicated by sudden cardiac death, heart failure, atrial fibrillation, and embolic stroke.[2 –4] With advances in management strategies including implantable cardioverter-defibrillators and anticoagulation, subjects with hypertrophic cardiomyopathy (HCM) are benefiting from extended longevity.
Source: Diabetes Research and Clinical Practice - March 18, 2022 Category: Endocrinology Authors: Hyun-Jung Lee, Hyung-Kwan Kim, Bong-Seong Kim, Kyung-Do Han, Tae-Min Rhee, Jun-Bean Park, Heesun Lee, Seung-Pyo Lee, Yong-Jin Kim Source Type: research

Endocrine Manifestations and New Developments in Mitochondrial Disease
Endocr Rev. 2022 May 12;43(3):583-609. doi: 10.1210/endrev/bnab036.ABSTRACTMitochondrial diseases are a group of common inherited diseases causing disruption of oxidative phosphorylation. Some patients with mitochondrial disease have endocrine manifestations, with diabetes mellitus being predominant but also include hypogonadism, hypoadrenalism, and hypoparathyroidism. There have been major developments in mitochondrial disease over the past decade that have major implications for all patients. The collection of large cohorts of patients has better defined the phenotype of mitochondrial diseases and the majority of patient...
Source: Endocrine Reviews - May 13, 2022 Category: Endocrinology Authors: Yi Shiau Ng Albert Zishen Lim Grigorios Panagiotou Doug M Turnbull Mark Walker Source Type: research

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