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Cancer: Colon Cancer
Drug: Magnesium

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Total 41 results found since Jan 2013.

Clinical and Prognostic Values of TRPM7 in Colon and Rectal Cancers
Conclusions: Our study highlights that TRPM7 expression in CRC, particularly in rectal cancer, may be a potential marker. Future studies are needed to provide deeper insights into the role of TRPM7 in rectal cancer.PMID:36363540 | DOI:10.3390/medicina58111582
Source: Medicina (Kaunas) - November 11, 2022 Category: Universities & Medical Training Authors: Jun-Chae Lee An-Na Bae Ha-Jin Lee Jae-Ho Lee Source Type: research

Pegylation of phenothiazine - A synthetic route towards potent anticancer drugs
CONCLUSION: Phenothiazine and PEG building blocks have a synergetic effect working for both tumour growth inhibition and biocompatibility improvement. All these findings recommend the PEGylated phenothiazine derivatives as a valuable workbench for a next generation of antitumor drugs.PMID:35499049 | PMC:PMC9040145 | DOI:10.1016/j.jare.2021.07.003
Source: Cell Research - May 2, 2022 Category: Cytology Authors: Sandu Cibotaru Valentin Nastasa Andreea-Isabela Sandu Andra-Cristina Bostanaru Mihai Mares Luminita Marin Source Type: research

A Comparison of Doxorubicin-Resistant Colon Cancer LoVo and Leukemia HL60 Cells: Common Features, Different Underlying Mechanisms
Curr Issues Mol Biol. 2021 May 22;43(1):163-175. doi: 10.3390/cimb43010014.ABSTRACTChemoresistance causes cancer relapse and metastasis, thus remaining the major obstacle to cancer therapy. While some light has been shed on the underlying mechanisms, it is clear that chemoresistance is a multifaceted problem strictly interconnected with the high heterogeneity of neoplastic cells. We utilized two different human cell lines, i.e., LoVo colon cancer and promyelocytic leukemia HL60 cells sensitive and resistant to doxorubicin (DXR), largely used as a chemotherapeutic and frequently leading to chemoresistance. LoVo and HL60 res...
Source: Current Issues in Molecular Biology - June 2, 2021 Category: Molecular Biology Authors: Laura Locatelli Alessandra Cazzaniga Giorgia Fedele Monica Zocchi Roberta Scrimieri Claudia Moscheni Sara Castiglioni Jeanette A Maier Source Type: research