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Specialty: Biochemistry
Cancer: Lung Cancer

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Total 78 results found since Jan 2013.

Prof. Transient receptor potential vanilloid 4 promotes the growth of non-small cell lung cancer by regulating Foxp3
CONCLUSIONS: Antitumor effects caused by TRPV4 inhibition in NSCLC might be attributed to the suppression of Foxp3 which induced subsequent cell apoptosis. Thus, pharmacological inhibition of TRPV4 may be a promising option for NSCLC treatment.PMID:34995050 | DOI:10.18388/abp.2020_5614
Source: Acta Biochim Pol - January 7, 2022 Category: Biochemistry Authors: Jiang-Tao Pu Tao Zhang Kai-Ming He Deng-Guo Zhang Zhang-Yu Teng Yun-Fei Wu Source Type: research

A novel EZH2/NXPH4/CDKN2A axis is involved in regulating the proliferation and migration of non-small cell lung cancer cells
Biosci Biotechnol Biochem. 2021 Dec 17:zbab217. doi: 10.1093/bbb/zbab217. Online ahead of print.ABSTRACTNXPH4 is discovered to be a neuropeptide-like glycoprotein, belonging to the Neurexophilins (Nxphs) family. NXPH4 shares a similar domain structure with NXPH1, which, however, is poorly understood in terms of its function. Bioinformatics analysis and experimental verification in this study confirmed the abnormal high expression of NXPH4 in non-small cell lung cancer (NSCLC) tissues and cells. Knockdown of NXPH4 by siRNA can inhibit the proliferation and migration of cells, resulting in significant cell cycle arrest in S1...
Source: Bioscience, Biotechnology, and Biochemistry - December 17, 2021 Category: Biochemistry Authors: Zeng Yang Bo Wei Anbang Qiao Popo Yang Wenhui Chen Dezhi Zhen Xiaojian Qiu Source Type: research

Silencing of survivin and cyclin B1 through siRNA-loaded arginine modified calcium phosphate nanoparticles for non-small-cell lung cancer therapy
Publication date: Available online 27 August 2020Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Goknur Kara, Ayhan Parlar, Melike Cokol Cakmak, Murat Cokol, Emir Baki Denkbas, Feray Bakan
Source: Colloids and Surfaces B: Biointerfaces - August 29, 2020 Category: Biochemistry Source Type: research