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Cancer: Hepatocellular Carcinoma
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Total 40824 results found since Jan 2013.
Mechanism of total glucosides from Chishao (Radix Paeoniae Rubra) on proliferation and apoptosis of hepatocellular carcinoma cells via phosphatase and tensin homolog deleted on chromosome ten / phosphatidylinositol 3-kinase / protein kinase B signaling pathway
CONCLUSION: TG-RPR significantly inhibits the proliferation of HepG2 cells in a dose-dependent manner and promotes apoptosis. These results demonstrated TG-RPR has significant inhibitory effect on HepG2 cells. These results identify a critical role of TG-RPR in proliferation and apoptosis of HepG2 cells via modulating PTEN/PI3K/Akt signaling pathway. TG-RPR may offer a promise as a potential pharmaceutical therapy for hepatocellular carcinoma.PMID:34708625 | DOI:10.19852/j.cnki.jtcm.2021.05.003
Source: Journal of Traditional Chinese Medicine - October 28, 2021 Category: Complementary Medicine Authors: Bing-Bing Fan Tian-Jiao Li Xian-Sheng Meng Shuai Wang Yong-Rui Bao Fei Wang Source Type: research
A pure nanoICG-based homogeneous lipiodol formulation: toward precise surgical navigation of primary liver cancer after long-term transcatheter arterial embolization
CONCLUSION: Such a simple and effective strategy provides a promising avenue to address the clinical issue of clinical hepatectomy and has excellent potential for a translational pipeline.PMID:34939176 | DOI:10.1007/s00259-021-05654-z
Source: Molecular Medicine - December 23, 2021 Category: Molecular Biology Authors: Yang Zhang Hongwei Cheng Hu Chen Peiyao Xu En Ren Yonghe Jiang Dengfeng Li Xing Gao Yating Zheng Pan He Huirong Lin Biaoqi Chen Gan Lin Aizheng Chen Chengchao Chu Jingsong Mao Gang Liu Source Type: research
ASIC1a stimulates the resistance of human hepatocellular carcinoma by promoting EMT via the AKT/GSK3 β/Snail pathway driven by TGFβ/Smad signals
J Cell Mol Med. 2022 Apr 14. doi: 10.1111/jcmm.17288. Online ahead of print.ABSTRACTMultidrug resistance is the main obstacle to curing hepatocellular carcinoma (HCC). Acid-sensing ion channel 1a (ASIC1a) has critical roles in all stages of cancer progression, especially invasion and metastasis, and in resistance to therapy. Epithelial to mesenchymal transition (EMT) transforms epithelial cells into mesenchymal cells after being stimulated by extracellular factors and is closely related to tumour infiltration and resistance. We used Western blotting, immunofluorescence, qRT-PCR, immunohistochemical staining, MTT, colony fo...
Source: Molecular Medicine - April 15, 2022 Category: Molecular Biology Authors: Yinci Zhang Niandie Cao Jiafeng Gao Jiaojiao Liang Yong Liang Yinghai Xie Shuping Zhou Xiaolong Tang Source Type: research
Prevention and Treatment of Hepatocellular Carcinoma Using miRNAs
This study provides the latest findings on using miRNAs in the control of HCC in both in vitro and in vivo models.PMID:35429953 | DOI:10.34172/aim.2022.23
Source: Archives of Iranian Medicine - April 17, 2022 Category: Middle East Health Authors: Zahra Farzaneh Maryam Farzaneh Source Type: research
