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Cancer: Squamous Cell Carcinoma

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Total 19037 results found since Jan 2013.

Metabolomics of Esophageal Squamous Cell Carcinoma Tissues: Potential Biomarkers for Diagnosis and Promising Targets for Therapy
CONCLUSIONS: From the metabolomic data, 4 unknown compounds were found to be abnormally expressed in esophageal squamous cell carcinoma for the first time, such as 9,10-epoxy-12,15-octadecadienoate; 3 metabolites were found in multiple abnormal expression in another tumor, but upregulation or downregulation was found for the first time in esophageal cancer, such as oleoyl glycine; at the same time, it was further confirmed that five metabolites were abnormally expressed in esophageal squamous cell carcinoma, which was similar to the results of other studies, such as PE.PMID:35782075 | PMC:PMC9246618 | DOI:10.1155/2022/7819235
Source: Biomed Res - July 5, 2022 Category: Research Authors: Jia Xu Weiping Cao Aizhong Shao Ming Yang Vivian Andoh Qi Ge Hui-Wen Pan Ke-Ping Chen Source Type: research

Does human papillomavirus modify the risk of oropharyngeal cancer related to smoking and alcohol drinking? A systematic review and meta-analysis
CONCLUSIONS: This meta-analysis suggests a negative directed interaction of HPV and smoking; and HPV and heavy alcohol drinking in the development of primary OPSCC on stratified analysis and joint effect analysis.LEVEL OF EVIDENCE: 3A.PMID:36258880 | PMC:PMC9575072 | DOI:10.1002/lio2.877
Source: Cancer Control - October 19, 2022 Category: Cancer & Oncology Authors: Rawan T Arif Meaad A Mogaddam Leena A Merdad Nada J Farsi Source Type: research

The Use of Salivary Levels of Matrix Metalloproteinases as an Adjuvant Method in the Early Diagnosis of Oral Squamous Cell Carcinoma: A Narrative Literature Review
Curr Issues Mol Biol. 2022 Dec 12;44(12):6306-6322. doi: 10.3390/cimb44120430.ABSTRACTOral squamous cell carcinoma (OSCC) is an aggressive malignancy with increased mortality, in which the early diagnosis is the most important step in increasing patients' survival rate. Extensive research has evaluated the role of saliva as a source of diagnostic biomarkers, among which matrix metalloproteinases (MMPs) have shown a valuable potential for detecting even early stages of OSCC. The aim of this review was to present recent clinical data regarding the significance of salivary MMPs in the detection of early malignant transformati...
Source: Current Issues in Molecular Biology - December 22, 2022 Category: Molecular Biology Authors: Monica Monea Anca Maria Pop Source Type: research