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Cancer: Melanoma
Therapy: Corticosteroid Therapy
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Total 292 results found since Jan 2013.
Antibiotic Treatment is an Independent Poor Risk Factor in NSCLC But Not in Melanoma Patients Who had Received Anti-PD-1/L1 Monotherapy
CONCLUSIONS: Early ABT was an independent poor risk factor in NSCLC patients who had received anti-PD-1/L1 monotherapy but not in melanoma patients. The weight of ABT as a poor risk factor might depend on other prognostic factors in different cancers.PMID:36774235 | DOI:10.1016/j.cllc.2023.01.004
Source: Clinical Lung Cancer - February 11, 2023 Category: Cancer & Oncology Authors: Hannes Vihinen Artturi Jokinen Teemu D Laajala Nesna Wahid Lotta Peltola Tiia Kettunen Aino R önkä Leena Tiainen Tanja Skytt ä Laura Kohtam äki Sanni Tulokas Hanna Karhap ää Micaela Hernberg Maria Silvoniemi Kalle E Mattila Source Type: research
Recurrence of Hypophysitis After Immune Checkpoint Inhibitor Rechallenge
We report a case of recurrent hypophysitis following ICI rechallenge for metastatic melanoma. A 33-year-old woman with recurrent metastatic melanoma with adrenal, pelvic, and inguinal metastases developed recurrent hypophysitis during treatment with ipilimumab and nivolumab which recurred with rechallenge >5 years later. In both cases, headache was the most notable symptom and brain MRI showed pituitary enlargement and edema without evidence of metastases. Central adrenal insufficiency and symptoms caused by mass effect were treated with acute high-dose corticosteroids and long-term replacement corticosteroids. Based on...
Source: The Oncologist - October 26, 2022 Category: Cancer & Oncology Authors: Benjamin C Park Seungyeon Jung Jordan J Wright Douglas B Johnson Source Type: research
Neurological adverse effects associated with anti-PD1 antibodies alone or in combination with ipilimumab: a multicenter case series
Melanoma Res. 2022 Sep 23. doi: 10.1097/CMR.0000000000000825. Online ahead of print.ABSTRACTAnti-programmed cell death protein 1 (PD1) antibodies, pembrolizumab and nivolumab, alone or in combination with ipilimumab, have become standard treatment for melanoma and multiple other malignancies. Neurological adverse effects are rare and have not been well characterized to date. Patients who developed neurological adverse effects while being treated with PD1, alone or in combination with ipilimumab, were retrospectively identified from 10 cancer centers. Fifty-eight patients were included, and the median time from treatment in...
Source: Cell Research - September 27, 2022 Category: Cytology Authors: Jessica Louise Smith Alexander M Menzies Justine V Cohen Margarida Mut-Lloret Alpaslan Ozgun Lavinia Spain John Park Henry T Quach Lalit Pallan Jennifer McQuade Sophie Feng Shahneen Sandhu Victoria Atkinson Katy Tsai Georgina V Long James Larkin Zeynep Er Source Type: research
Interstitial granulomatous dermatitis and concurrent immunotherapy associated encephalitis with nivolumab and ipilimumab
We present a 73-year-old man with dementia and metastatic melanoma who developed immunotherapy-associated encephalitis and subsequently, interstitial granulomatous dermatitis with nivolumab/ipilimumab. High-dose corticosteroids successfully treated both conditions, though he never regained his baseline mental status. We review the literature on interstitial granulomatous dermatitis and encephalitis with immunotherapy.PMID:35670686 | DOI:10.5070/D328257399
Source: Dermatol Online J - June 7, 2022 Category: Dermatology Authors: Caroline T Starling Alison A Messer Anne Kleiman Jennifer L McQuade Isabella C Glitza Carlos Antonio Torres-Cabala Meghan Heberton Source Type: research
A case of nivolumab-induced bullous pemphigoid successfully treated with dupilumab
Dermatol Online J. 2022 Mar 15;28(2). doi: 10.5070/D328257396.ABSTRACTA 76-year-old man came to our attention for the presence of itchy skin lesions localized on the trunk. The patient had a nodular melanoma removed two years earlier. Because of metastatic pulmonary melanoma, he underwent a lung lobectomy and began adjuvant therapy with nivolumab. After six months of treatment, the patient reported the appearance of itchy lesions on the trunk that were diagnosed as eczema and successfully treated with systemic corticosteroids. Upon corticosteroid discontinuation, the eruption relapsed presenting with erythematous macules, ...
Source: Dermatol Online J - June 7, 2022 Category: Dermatology Authors: Manfredo Bruni Agata Moar Donatella Schena Giampiero Girolomoni Source Type: research
Interstitial granulomatous dermatitis and concurrent immunotherapy associated encephalitis with nivolumab and ipilimumab
We present a 73-year-old man with dementia and metastatic melanoma who developed immunotherapy-associated encephalitis and subsequently, interstitial granulomatous dermatitis with nivolumab/ipilimumab. High-dose corticosteroids successfully treated both conditions, though he never regained his baseline mental status. We review the literature on interstitial granulomatous dermatitis and encephalitis with immunotherapy.PMID:35670686 | DOI:10.5070/D328257399
Source: Dermatol Online J - June 7, 2022 Category: Dermatology Authors: Caroline T Starling Alison A Messer Anne Kleiman Jennifer L McQuade Isabella C Glitza Carlos Antonio Torres-Cabala Meghan Heberton Source Type: research
A case of nivolumab-induced bullous pemphigoid successfully treated with dupilumab
Dermatol Online J. 2022 Mar 15;28(2). doi: 10.5070/D328257396.ABSTRACTA 76-year-old man came to our attention for the presence of itchy skin lesions localized on the trunk. The patient had a nodular melanoma removed two years earlier. Because of metastatic pulmonary melanoma, he underwent a lung lobectomy and began adjuvant therapy with nivolumab. After six months of treatment, the patient reported the appearance of itchy lesions on the trunk that were diagnosed as eczema and successfully treated with systemic corticosteroids. Upon corticosteroid discontinuation, the eruption relapsed presenting with erythematous macules, ...
Source: Dermatol Online J - June 7, 2022 Category: Dermatology Authors: Manfredo Bruni Agata Moar Donatella Schena Giampiero Girolomoni Source Type: research
Interstitial granulomatous dermatitis and concurrent immunotherapy associated encephalitis with nivolumab and ipilimumab
We present a 73-year-old man with dementia and metastatic melanoma who developed immunotherapy-associated encephalitis and subsequently, interstitial granulomatous dermatitis with nivolumab/ipilimumab. High-dose corticosteroids successfully treated both conditions, though he never regained his baseline mental status. We review the literature on interstitial granulomatous dermatitis and encephalitis with immunotherapy.PMID:35670686 | DOI:10.5070/D328257399
Source: Dermatol Online J - June 7, 2022 Category: Dermatology Authors: Caroline T Starling Alison A Messer Anne Kleiman Jennifer L McQuade Isabella C Glitza Carlos Antonio Torres-Cabala Meghan Heberton Source Type: research
A case of nivolumab-induced bullous pemphigoid successfully treated with dupilumab
Dermatol Online J. 2022 Mar 15;28(2). doi: 10.5070/D328257396.ABSTRACTA 76-year-old man came to our attention for the presence of itchy skin lesions localized on the trunk. The patient had a nodular melanoma removed two years earlier. Because of metastatic pulmonary melanoma, he underwent a lung lobectomy and began adjuvant therapy with nivolumab. After six months of treatment, the patient reported the appearance of itchy lesions on the trunk that were diagnosed as eczema and successfully treated with systemic corticosteroids. Upon corticosteroid discontinuation, the eruption relapsed presenting with erythematous macules, ...
Source: Dermatol Online J - June 7, 2022 Category: Dermatology Authors: Manfredo Bruni Agata Moar Donatella Schena Giampiero Girolomoni Source Type: research
Interstitial granulomatous dermatitis and concurrent immunotherapy associated encephalitis with nivolumab and ipilimumab
We present a 73-year-old man with dementia and metastatic melanoma who developed immunotherapy-associated encephalitis and subsequently, interstitial granulomatous dermatitis with nivolumab/ipilimumab. High-dose corticosteroids successfully treated both conditions, though he never regained his baseline mental status. We review the literature on interstitial granulomatous dermatitis and encephalitis with immunotherapy.PMID:35670686 | DOI:10.5070/D328257399
Source: Dermatol Online J - June 7, 2022 Category: Dermatology Authors: Caroline T Starling Alison A Messer Anne Kleiman Jennifer L McQuade Isabella C Glitza Carlos Antonio Torres-Cabala Meghan Heberton Source Type: research
A case of nivolumab-induced bullous pemphigoid successfully treated with dupilumab
Dermatol Online J. 2022 Mar 15;28(2). doi: 10.5070/D328257396.ABSTRACTA 76-year-old man came to our attention for the presence of itchy skin lesions localized on the trunk. The patient had a nodular melanoma removed two years earlier. Because of metastatic pulmonary melanoma, he underwent a lung lobectomy and began adjuvant therapy with nivolumab. After six months of treatment, the patient reported the appearance of itchy lesions on the trunk that were diagnosed as eczema and successfully treated with systemic corticosteroids. Upon corticosteroid discontinuation, the eruption relapsed presenting with erythematous macules, ...
Source: Dermatol Online J - June 7, 2022 Category: Dermatology Authors: Manfredo Bruni Agata Moar Donatella Schena Giampiero Girolomoni Source Type: research
Interstitial granulomatous dermatitis and concurrent immunotherapy associated encephalitis with nivolumab and ipilimumab
We present a 73-year-old man with dementia and metastatic melanoma who developed immunotherapy-associated encephalitis and subsequently, interstitial granulomatous dermatitis with nivolumab/ipilimumab. High-dose corticosteroids successfully treated both conditions, though he never regained his baseline mental status. We review the literature on interstitial granulomatous dermatitis and encephalitis with immunotherapy.PMID:35670686 | DOI:10.5070/D328257399
Source: Dermatol Online J - June 7, 2022 Category: Dermatology Authors: Caroline T Starling Alison A Messer Anne Kleiman Jennifer L McQuade Isabella C Glitza Carlos Antonio Torres-Cabala Meghan Heberton Source Type: research
A case of nivolumab-induced bullous pemphigoid successfully treated with dupilumab
Dermatol Online J. 2022 Mar 15;28(2). doi: 10.5070/D328257396.ABSTRACTA 76-year-old man came to our attention for the presence of itchy skin lesions localized on the trunk. The patient had a nodular melanoma removed two years earlier. Because of metastatic pulmonary melanoma, he underwent a lung lobectomy and began adjuvant therapy with nivolumab. After six months of treatment, the patient reported the appearance of itchy lesions on the trunk that were diagnosed as eczema and successfully treated with systemic corticosteroids. Upon corticosteroid discontinuation, the eruption relapsed presenting with erythematous macules, ...
Source: Dermatol Online J - June 7, 2022 Category: Dermatology Authors: Manfredo Bruni Agata Moar Donatella Schena Giampiero Girolomoni Source Type: research
