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Total 123 results found since Jan 2013.
X-ray and MR Contrast Bearing Nanoparticles Enhance the Therapeutic Response of Image-Guided Radiation Therapy for Oral Cancer
CONCLUSIONS: Theranostic nanoparticles enable preprocedure radiotherapy planning, as well as enhance radiation treatment efficacy for head and neck tumors.PMID:37469184 | PMC:PMC10363893 | DOI:10.1177/15330338231189593
Source: Technology in Cancer Research and Treatment - July 20, 2023 Category: Cancer & Oncology Authors: Gayatri Sharma Mir Hadi Razeghi Kondelaji Guru P Sharma Christopher Hansen Abdul K Parchur Shayan Shafiee Jaidip M Jagtap Brian Fish Carmen Bergom Eric Paulson William A Hall Heather A Himburg Amit Joshi Source Type: research
Telomerase reverse transcriptase immunohistochemical expression is sensitive but not specific for TERT gene amplification in acral melanoma
CONCLUSIONS: The clinical utility of TERT IHC to predict TGA status in AMs appears to be limited given its low specificity and positive predictive value.PMID:37400233 | DOI:10.1111/cup.14494
Source: Cancer Control - July 3, 2023 Category: Cancer & Oncology Authors: Woo Cheal Cho Wen Li Jun Gu Wei-Lien Wang Jing Ning Steven Sfamenos Pavandeep Gill Priyadharsini Nagarajan Jonathan L Curry Alexander J Lazar Victor G Prieto Carlos A Torres-Cabala Phyu P Aung Source Type: research
GRM1 gene fusions as an alternative molecular driver in blue nevi and related melanomas
Mod Pathol. 2023 Jun 28:100264. doi: 10.1016/j.modpat.2023.100264. Online ahead of print.ABSTRACTActivating mutations in GNAQ, GNA11, CYSLTR2, and PLCB4 genes are regarded as the main oncogenic drivers of blue nevi (BN) and blue malignant melanocytic tumors. Here we report four cases of blue melanocytic neoplasms devoid of these mutations but harboring GRM1 gene fusions. In this short series, there was no gender predominance (sex ratio = 1). The mean age at diagnosis was 40 years (range: 12-72). Tumors were located on the face (n=2), forearm (n=1) and dorsum of the foot (n=1). Clinically, a plaque-like pre-existing blue ne...
Source: Cancer Control - June 30, 2023 Category: Cancer & Oncology Authors: Thibault Kervarrec Giuseppe Lo Bello Daniel Pissaloux Franck Tirode Nicolas Poulalhon Mahtab Samimi Aurelie Houlier Arnaud de la Fouchardiere Source Type: research
Uric acid is a major chemical constituent for the whitish coloration in the medaka leucophores
Pigment Cell Melanoma Res. 2023 May 30. doi: 10.1111/pcmr.13102. Online ahead of print.ABSTRACTIn whitish parts of teleost skin, the coloration is attributed to a light scattering phenomenon within light-reflecting chromatophores, namely leucophores and iridophores, which contain high refractive index materials in their cytoplasmic organelles, leucosomes and light-reflecting platelets, respectively. Previous chemical examinations revealed that guanine is a major constituent of the materials in the platelets of the iridophores, while, in leucophores, the detailed chemical nature of the materials contained in the leucosomes ...
Source: Pigment Cell and Melanoma Research - May 30, 2023 Category: Cytology Authors: Makoto Goda Asuka Miyagi Takuya Kitamoto Minako Kondo Hisashi Hashimoto Source Type: research
