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Specialty: Urology & Nephrology
Cancer: Kidney Cancer

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Total 2245 results found since Jan 2013.

Real-world clinical outcomes of patients with metastatic renal cell carcinoma receiving pembrolizumab  + axitinib vs. ipilimumab + nivolumab
CONCLUSIONS: Our study provides insight into newer mccRCC treatment tolerability and effectiveness in the real-world US community setting. Our real-world results were comparable to data from clinical trials, which is encouraging for mccRCC patients.PMID:37722984 | DOI:10.1016/j.urolonc.2023.08.009
Source: Urologic Oncology - September 18, 2023 Category: Urology & Nephrology Authors: Neil J Shah Sneha D Sura Reshma Shinde Junxin Shi Puneet Singhal Rodolfo F Perini Robert J Motzer Source Type: research

Incidence of urological tumors in Down ’s syndrome: a systematic review and meta-analysis
ConclusionThere was a very low incidence of urological tumors in people with Down ’s syndrome. Testis tumor was the most frequently described in all cohorts and within a normal distribution range.
Source: International Urology and Nephrology - September 14, 2023 Category: Urology & Nephrology Source Type: research

Socioeconomic determinants of racial disparities in survival outcomes among patients with renal cell carcinoma
CONCLUSIONS: Black patients with RCC demonstrate worse survival outcomes compared to White patients across all stages. Socioeconomic disparities between races play a significant role in influencing survival in RCC.PMID:37709565 | DOI:10.1016/j.urolonc.2023.08.016
Source: Urologic Oncology - September 14, 2023 Category: Urology & Nephrology Authors: Ridwan Alam Michael E Rezaee Maximilian Pallauf Roy Elias Anirudh Yerrapragada Dmitry Enikeev Dong Fang Shahrokh F Shariat Solomon L Woldu Yasser M A Ged Nirmish Singla Source Type: research

Assessing the impact of lymphovascular invasion on overall survival in surgically treated renal cell carcinoma patients: A nationwide cohort analysis
CONCLUSIONS: Our findings are the first, to our best knowledge, to illustrate the clear detrimental impact of LVI on OS in surgically treated RCC patients. These findings might be useful in postoperative patient counseling and need to be accounted for when designing future clinical trials.PMID:37625905 | DOI:10.1016/j.urolonc.2023.07.011
Source: Urologic Oncology - August 25, 2023 Category: Urology & Nephrology Authors: Ivan Rakic Nikola Rakic Alex Stephens Nicholas Corsi Matt Davis Shane Tinsley Mohit Butaney Sohrab Arora Akshay Sood Riccardo Autorino Craig Rogers Firas Abdollah Source Type: research

Human parietal epithelial cells (PECs) and proteinuria in lupus nephritis: a role for ClC-5, megalin, and cubilin?
CONCLUSIONS: Our results may provide further insight into the role of hypertrophic parietal epithelial cells located at the tubular pole and their possible involvement in protein endocytosis in lupus nephritis patients. These data also suggest that the presence of hypertrophic parietal epithelial cells in Bowman's capsule represents a potential resource for responding to protein overload observed in other glomerulonephritis.PMID:37594671 | DOI:10.1007/s40620-023-01725-6
Source: Journal of Nephrology - August 18, 2023 Category: Urology & Nephrology Authors: Monica Ceol Lisa Gianesello Hernan Trimarchi Alberto Migliorini Giovanna Priante Claudia M Radu Elena Naso Annalisa Angelini Lorenzo A Cal ò Franca Anglani Dorella Del Prete Source Type: research

Incidence and clinical relevance of paraneoplastic syndromes in patients with renal cell carcinoma
CONCLUSIONS: Using EMR data, laboratory evidence of PNS was present in one-third of a contemporary cohort of patients undergoing nephrectomy, with >50% of PNS resolving after surgery. Consistent with prior reports, PNS are more common in higher-stage RCC and are associated with poorer survival in RCC patients.PMID:37537025 | DOI:10.1016/j.urolonc.2023.06.015
Source: Urologic Oncology - August 3, 2023 Category: Urology & Nephrology Authors: Tudor Moldovan Dennis Boynton Joshua Kuperus Jessica Parker Sabrina L Noyes Christopher M Brede Conrad M Tobert Brian R Lane Source Type: research

End-stage kidney disease: a never healing wound leading to another never healing wound, renal cancer
CONCLUSION: The progressive inflammatory and fibrotic processes in end-stage kidney disease have features recalling those of a never healing wound and may explain the frequent development of kidney cancer.PMID:37439962 | DOI:10.1007/s40620-023-01694-w
Source: Journal of Nephrology - July 13, 2023 Category: Urology & Nephrology Authors: Janos Docs Gyula Kovacs Lehel Peterfi Source Type: research