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Aerobic Exercise Regulates Apoptosis through the PI3K/Akt/GSK-3 < em > β < /em > Signaling Pathway to Improve Cognitive Impairment in Alzheimer's Disease Mice
Neural Plast. 2022 Sep 10;2022:1500710. doi: 10.1155/2022/1500710. eCollection 2022.ABSTRACTNeuronal apoptosis is an important factor in the etiology of Alzheimer's disease (AD). Aerobic exercise (AE) enhances learning and memory, improves cognitive impairment, increases telomere binding protein expression, and decreases apoptosis regulators, but it remains unclear whether it can improve cognitive impairment caused by neuronal apoptosis in AD. Therefore, this study investigated whether an 8-week running table exercise intervention could reduce apoptosis and improve cognitive function in the hippocampal neurons of AD model ...
Source: Neural Plasticity - September 20, 2022 Category: Neurology Authors: Yan Peng Rui Chi Gang Liu Weijie Tian Jun Zhang Rihui Zhang Source Type: research
Urothelial Carcinoma With Pulmonary Tumor Thrombotic Microangiopathy After Chemotherapy for Hodgkin Lymphoma
In this report, the autopsy findings of a patient with HL, who was in complete remission after chemotherapy but expired of pulmonary tumor thrombotic microangiopathy (PTTM) caused by urothelial carcinoma of the renal pelvis (UCRP), were described. A 78-year-old Japanese man with a history of classical HL developed irreversible heart failure about 2.5 years after chemotherapy. The patient expired shortly after being admitted due to ineffective treatment for heart failure. However, the cause of death was not determined. The patient's autopsy findings revealed UCRP in the left kidney, as well as infiltration around the inferi...
Source: Clin Med Res - September 21, 2022 Category: Research Authors: Naomi Shimizu Takuro Ito Shuji Sato Yoshiya Sugiura Ichiro Tatsuno Source Type: research
Aerobic Exercise Regulates Apoptosis through the PI3K/Akt/GSK-3 < em > β < /em > Signaling Pathway to Improve Cognitive Impairment in Alzheimer's Disease Mice
Neural Plast. 2022 Sep 10;2022:1500710. doi: 10.1155/2022/1500710. eCollection 2022.ABSTRACTNeuronal apoptosis is an important factor in the etiology of Alzheimer's disease (AD). Aerobic exercise (AE) enhances learning and memory, improves cognitive impairment, increases telomere binding protein expression, and decreases apoptosis regulators, but it remains unclear whether it can improve cognitive impairment caused by neuronal apoptosis in AD. Therefore, this study investigated whether an 8-week running table exercise intervention could reduce apoptosis and improve cognitive function in the hippocampal neurons of AD model ...
Source: Neural Plasticity - September 20, 2022 Category: Neurology Authors: Yan Peng Rui Chi Gang Liu Weijie Tian Jun Zhang Rihui Zhang Source Type: research
Urothelial Carcinoma With Pulmonary Tumor Thrombotic Microangiopathy After Chemotherapy for Hodgkin Lymphoma
In this report, the autopsy findings of a patient with HL, who was in complete remission after chemotherapy but expired of pulmonary tumor thrombotic microangiopathy (PTTM) caused by urothelial carcinoma of the renal pelvis (UCRP), were described. A 78-year-old Japanese man with a history of classical HL developed irreversible heart failure about 2.5 years after chemotherapy. The patient expired shortly after being admitted due to ineffective treatment for heart failure. However, the cause of death was not determined. The patient's autopsy findings revealed UCRP in the left kidney, as well as infiltration around the inferi...
Source: Clin Med Res - September 21, 2022 Category: Research Authors: Naomi Shimizu Takuro Ito Shuji Sato Yoshiya Sugiura Ichiro Tatsuno Source Type: research
Aerobic Exercise Regulates Apoptosis through the PI3K/Akt/GSK-3 < em > β < /em > Signaling Pathway to Improve Cognitive Impairment in Alzheimer's Disease Mice
Neural Plast. 2022 Sep 10;2022:1500710. doi: 10.1155/2022/1500710. eCollection 2022.ABSTRACTNeuronal apoptosis is an important factor in the etiology of Alzheimer's disease (AD). Aerobic exercise (AE) enhances learning and memory, improves cognitive impairment, increases telomere binding protein expression, and decreases apoptosis regulators, but it remains unclear whether it can improve cognitive impairment caused by neuronal apoptosis in AD. Therefore, this study investigated whether an 8-week running table exercise intervention could reduce apoptosis and improve cognitive function in the hippocampal neurons of AD model ...
Source: Neural Plasticity - September 20, 2022 Category: Neurology Authors: Yan Peng Rui Chi Gang Liu Weijie Tian Jun Zhang Rihui Zhang Source Type: research
Urothelial Carcinoma With Pulmonary Tumor Thrombotic Microangiopathy After Chemotherapy for Hodgkin Lymphoma
In this report, the autopsy findings of a patient with HL, who was in complete remission after chemotherapy but expired of pulmonary tumor thrombotic microangiopathy (PTTM) caused by urothelial carcinoma of the renal pelvis (UCRP), were described. A 78-year-old Japanese man with a history of classical HL developed irreversible heart failure about 2.5 years after chemotherapy. The patient expired shortly after being admitted due to ineffective treatment for heart failure. However, the cause of death was not determined. The patient's autopsy findings revealed UCRP in the left kidney, as well as infiltration around the inferi...
Source: Clin Med Res - September 21, 2022 Category: Research Authors: Naomi Shimizu Takuro Ito Shuji Sato Yoshiya Sugiura Ichiro Tatsuno Source Type: research
Meta-Analysis of Survival Effects of Receptor Tyrosine Kinase-like Orphan Receptor 1 (ROR1)
Conclusions: This meta-analysis provides evidence that ROR1 expression is associated with adverse outcome in cancer survival. This result highlights ROR1 as a target for developmental therapeutics in cancers.PMID:36557069 | PMC:PMC9784027 | DOI:10.3390/medicina58121867
Source: Medicina (Kaunas) - December 23, 2022 Category: Universities & Medical Training Authors: Soo Young Jeong Kyung-Jun Lee Jieum Cha So Yoon Park Hyeong Su Kim Jung Han Kim Jae-Jun Lee Namhyeok Kim Sung Taek Park Source Type: research
