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Two medical pioneers aim to trial a cancer-killing virus. I aim to help out | Alexander Masters
A pair of researchers in Sweden may have a revolutionary cancer treatment on their hands. But a separate revolution will be needed to get it to marketJust north of Stockholm, among the creaking Swedish ice-forests, three revolutions for 2013 are taking place.Revolution One: Two researchers at the University of Uppsala have engineered a virus that will attack cancer. Cheap, precise, with only mild, flu-like side-effects, this plucky little microbe sounds too good to be true. Yet in peer-reviewed articles in top journals, Professor Magnus Essand and Dr Justyna Leja have repeatedly showed that Ad5[CgA-E1A-miR122]PTD views hea...
Source: Guardian Unlimited Science - January 4, 2013 Category: Science Authors: Alexander Masters Tags: Comment The Guardian Crowdsourcing Health Medical research Society Technology Kickstarter Features Cancer Internet Science Comment is free Source Type: news

Pd2-2 * a tough road to get jcog1111 ready to start under the advanced medical service system(senshin iryou b)
Adult T-cell leukemia/lymphoma (ATL) is a malignancy of Th2/Treg cells associated with HTLV-1, and its prognosis is still very poor. ATL is endemic in Japan, but the number of newly-diagnosed patients is limited to approximately 1200/year, while it is much rare in the rest of the world. ATL had been paid little interest to develop novel agents by pharmaceutical industries, mainly due to its rarity. The standard of care in Japan for indolent ATL (iATL) is watch and wait strategy until transformation to aggressive ATL, while early intervention by interferon-alpha and zidovudine (IFN/AZT) is reported to be a standard of care ...
Source: Annals of Oncology - October 19, 2014 Category: Cancer & Oncology Authors: Ishitsuka, K. Tags: Panel Discussion 2: ' Role of special medical system to develop new cancer treatment Source Type: research

Hemorrhagic cystitis in children treated with alkylating agent cyclophosphamide: The experience of a medical center in Taiwan
Conclusion Alteration serum uric acid level and BMT could be indicators for severe hemorrhagic cystitis. The elevated levels of urinary nitrite/nitrate and 8-iso-prostaglandin F2α may indicate the essential roles played by nitric oxide syntheses and reactive oxidative stress in cyclophosphamide-induced hemorrhagic cystitis. These findings may help clinicians formulate a better strategy for treating cyclophosphamide-induced hemorrhagic cystitis.
Source: Journal of the Formosan Medical Association - August 5, 2015 Category: Journals (General) Source Type: research

241. Radiation risk due to medical imaging in long living patients: the case of Hodgkin lymphoma
Serious concern were risen in the scientific community on the risk of second cancer due to medical imaging in long-living cohort of patients with advanced stage Hodgkin Lymphoma (HL). The purpose of this work was to analyze a cohort of patient enrolled in a clinical trial to understand the type and number of medical examination performed by the patients and estimate the cumulative effective dose.
Source: Physica Medica: European Journal of Medical Physics - December 1, 2018 Category: General Medicine Authors: S. Chauvie, N. Acchiardi, A. De Maggi, E. Roberto, F. Bergesio Source Type: research

Prevalence and determinants of distress among oncology patients at a tertiary care medical city in Riyadh, Saudi Arabia
CONCLUSION: Approximately half of cancer patients were found to have distress. Anxiety, advanced cancer stage, and radiotherapy were independently associated with distress.PMID:34187920 | DOI:10.15537/smj.2021.42.7.20210121
Source: Saudi Medical Journal - June 30, 2021 Category: Middle East Health Authors: Luluh Y Alsughayer Lamees A Altamimi Futoon S Alsaleh Lamya Alsaghan Ibrahim Alfurayh Nashwa M Abdel-Aziz Khalid A Alsaleh Fahad D Alosaimi Source Type: research